Results 41 to 50 of about 26,169 (207)

A Kinetic Study of CD83 Reveals an Upregulation and Higher Production of sCD83 in Lymphocytes from Pregnant Mice

Frontiers in Immunology, 2017
For the normal development of pregnancy, a balance between immune tolerance and defense is crucial. However, the mechanisms mediating such a balance are not fully understood.
Damián Oscar Muzzio, Katrin Regina Helene Packhäuser, Gleyder Roman-Sosa, Jens Ehrhardt, Diana Krüger, Marek Zygmunt   +5 more
doaj   +1 more source

Eubacterium rectale Attenuates HSV-1 Induced Systemic Inflammation in Mice by Inhibiting CD83

Frontiers in Immunology, 2021
The purpose of this study was to determine whether administration of the microorganism Eubacterium rectale (E. rectale) could regulate dendritic cell (DC) activation and systemic inflammation in herpes simplex virus type 1-induced Behçet’s disease (BD ...
S. M. Shamsul Islam, Hye-Myung Ryu, Hasan M. Sayeed, Hae-Ok Byun, Ju-Yang Jung, Hyoun-Ah Kim, Chang-Hee Suh, Chang-Hee Suh, Seonghyang Sohn, Seonghyang Sohn   +9 more
doaj   +1 more source

Docosahexaenoic acid (DHA) promotes immunogenic apoptosis in human multiple myeloma cells, induces autophagy and inhibits STAT3 in both tumor and dendritic cells [PDF]

, 2017
Docosahexaenoic acid (DHA), a ω-3 polyunsaturated fatty acid found in fish oil, is a multi-target agent and exerts anti-inflammatory and anticancer activities alone or in combination with chemotherapies.
D'Eliseo, Donatella, DI RENZO, Livia Maria, Santoni, Angela, Velotti, Francesca   +3 more
core   +1 more source

The transcription factor Foxo1 controls germinal center B cell proliferation in response to T cell help [PDF]

, 2017
Germinal center (GC) B cells cycle between two states, the light zone (LZ) and the dark zone (DZ), and in the latter they proliferate and hypermutate their immunoglobulin genes. How this functional transition takes place is still controversial.
Allen, Bannard, Bonifaz, Boscardin, Calado, Chambers, Chie Kawai, Dansen, De Silva, Dominguez-Sola, Dominguez-Sola, Dorsey, Draghi, Dubrovska, Gitlin, Gitlin, Gong, Hedrick, Huang, Inoue, Ise, Itano, Kitamura, Kurosaki, Kuwahara, Liu, Murphy, Murphy, Paik, Pape, Rickert, Ryo Shinnakasu, Safford, Sagardoy, Sander, Schwickert, Shih, Shinnakasu, Shlomchik, Subramanian, Takeshi Egawa, Takeshi Inoue, Taylor, Toellner, Tomohiro Kurosaki, Trinh, Victora, Victora, Victora, Victora, Wataru Ise, Zhang, Zheng   +52 more
core   +2 more sources

Involvement of Caveolin-1 in CD83 Internalization in Mouse Dendritic Cells

Cell Transplantation, 2015
To become potent T-cell stimulators, DCs need to mature. Treatment with soluble CD83 (sCD83) induces immune tolerance and protects against transplant rejection by maintaining dendritic cells in an immature, tolerogenic state.
Yuejing Yang, Zhongcheng Xin, Jingjia Chu, Na Li, Tao Sun M.D., Ph.D.   +4 more
doaj   +1 more source

Identification of dendritic cell precursor from the CD11c+ cells expressing high levels of MHC class II molecules in the culture of bone marrow with FLT3 ligand

Frontiers in Immunology, 2023
Dendritic cells (DCs) are readily generated from the culture of mouse bone marrow (BM) treated with either granulocyte macrophage-colony stimulating factor (GM-CSF) or FMS-like tyrosine kinase 3 ligand (FLT3L).
Hyunju In, Hyunju In, Ji Soo Park, Ji Soo Park, Hyun Soo Shin, Hyun Soo Shin, Seul Hye Ryu, Seul Hye Ryu, Seul Hye Ryu, Moah Sohn, Moah Sohn, Wanho Choi, Wanho Choi, Sejung Park, Sejung Park, Soomin Hwang, Soomin Hwang, Jeyun Park, Lihua Che, Lihua Che, Tae-Gyun Kim, Min Kyung Chu, Hye Young Na, Hye Young Na, Chae Gyu Park, Chae Gyu Park, Chae Gyu Park   +26 more
doaj   +1 more source

Inhibition of HIF-1 alpha by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma [PDF]

, 2015
This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Acland, Assenat, Bazhin, Carbone, Chaput, Chen, Chouaib, Danenberg, David, Dyson, El-Deiry, Gallick, Gelovani, Ghansah, Giese, Gil, Gress, Gribben, Hao, Hao, Hao, Henson, Jemal, Kiessling, Kroemer, Kroemer, Kroemer, Levi, Luo, Mi, Moses, Plate, Powis, Powis, Powis, Ravichandran, Ricci, Rodeck, Sarker, Schuler, Semenza, Singh, Spisek, Tani, Vandenabeele, Wang, Wang, Zitvogel, Zitvogel, Zitvogel   +49 more
core   +1 more source

CD83 Expression in CD4+ T Cells Modulates Inflammation and Autoimmunity [PDF]

The Journal of Immunology, 2008
Abstract The transmembrane protein CD83 has been initially described as a maturation marker for dendritic cells. Moreover, there is increasing evidence that CD83 also regulates B cell function, thymic T cell maturation, and peripheral T cell activation.
Reinwald, Simone, Wiethe, Carsten, Westendorf, Astrid, Breloer, Minka, Probst-Kepper, Michael, Fleischer, Bernhard, Steinkasserer, Alexander, Buer, Jan, Hansen, Wiebke   +8 more
openaire   +2 more sources

Endogenous Expression of the Human CD83 Attenuates EAE Symptoms in Humanized Transgenic Mice and Increases the Activity of Regulatory T Cells

Frontiers in Immunology, 2019
The CD83 is a type I membrane protein and part of the immunoglobulin superfamily of receptors. CD83 is involved in the regulation of antigen presentation and dendritic cell dependent allogeneic T cell proliferation.
Elisabeth Zinser, Ronald Naumann, Andreas B. Wild, Julia Michalski, Andrea Deinzer, Lena Stich, Christine Kuhnt, Alexander Steinkasserer, Ilka Knippertz   +8 more
doaj   +1 more source

Cutting Edge: CD83 Regulates the Development of Cellular Immunity [PDF]

The Journal of Immunology, 2002
Abstract We recently found that human CD83, a marker of mature dendritic cells, is an adhesion receptor that binds to resting monocytes and a subset of activated CD8+ T cells. We injected CD83-Ig into mice transplanted with the immunogenic P815 mastocytoma and showed that it significantly enhanced the rate of tumor growth and inhibited ...
Nathalie, Scholler, Martha, Hayden-Ledbetter, Amber, Dahlin, Ingegerd, Hellström, Karl Erik, Hellström, Jeffrey A, Ledbetter   +5 more
openaire   +2 more sources