Results 31 to 40 of about 16,344 (174)

Homologs of CD83 from Elasmobranch and Teleost Fish [PDF]

The Journal of Immunology, 2004
Abstract Dendritic cells are one of the most important cell types connecting innate and adaptive immunity, but very little is known about their evolutionary origins. To begin to study dendritic cells from lower vertebrates, we isolated and characterized CD83 from the nurse shark (Ginglymostoma cirratum (Gici)) and rainbow trout ...
Yuko, Ohta, Eric, Landis, Thomas, Boulay, Ruth B, Phillips, Bertrand, Collet, Chris J, Secombes, Martin F, Flajnik, John D, Hansen   +7 more
openaire   +2 more sources

A Kinetic Study of CD83 Reveals an Upregulation and Higher Production of sCD83 in Lymphocytes from Pregnant Mice

Frontiers in Immunology, 2017
For the normal development of pregnancy, a balance between immune tolerance and defense is crucial. However, the mechanisms mediating such a balance are not fully understood.
Damián Oscar Muzzio, Katrin Regina Helene Packhäuser, Gleyder Roman-Sosa, Jens Ehrhardt, Diana Krüger, Marek Zygmunt   +5 more
doaj   +1 more source

Eubacterium rectale Attenuates HSV-1 Induced Systemic Inflammation in Mice by Inhibiting CD83

Frontiers in Immunology, 2021
The purpose of this study was to determine whether administration of the microorganism Eubacterium rectale (E. rectale) could regulate dendritic cell (DC) activation and systemic inflammation in herpes simplex virus type 1-induced Behçet’s disease (BD ...
S. M. Shamsul Islam, Hye-Myung Ryu, Hasan M. Sayeed, Hae-Ok Byun, Ju-Yang Jung, Hyoun-Ah Kim, Chang-Hee Suh, Chang-Hee Suh, Seonghyang Sohn, Seonghyang Sohn   +9 more
doaj   +1 more source

Involvement of Caveolin-1 in CD83 Internalization in Mouse Dendritic Cells

Cell Transplantation, 2015
To become potent T-cell stimulators, DCs need to mature. Treatment with soluble CD83 (sCD83) induces immune tolerance and protects against transplant rejection by maintaining dendritic cells in an immature, tolerogenic state.
Yuejing Yang, Zhongcheng Xin, Jingjia Chu, Na Li, Tao Sun M.D., Ph.D.   +4 more
doaj   +1 more source

Identification of dendritic cell precursor from the CD11c+ cells expressing high levels of MHC class II molecules in the culture of bone marrow with FLT3 ligand

Frontiers in Immunology, 2023
Dendritic cells (DCs) are readily generated from the culture of mouse bone marrow (BM) treated with either granulocyte macrophage-colony stimulating factor (GM-CSF) or FMS-like tyrosine kinase 3 ligand (FLT3L).
Hyunju In, Hyunju In, Ji Soo Park, Ji Soo Park, Hyun Soo Shin, Hyun Soo Shin, Seul Hye Ryu, Seul Hye Ryu, Seul Hye Ryu, Moah Sohn, Moah Sohn, Wanho Choi, Wanho Choi, Sejung Park, Sejung Park, Soomin Hwang, Soomin Hwang, Jeyun Park, Lihua Che, Lihua Che, Tae-Gyun Kim, Min Kyung Chu, Hye Young Na, Hye Young Na, Chae Gyu Park, Chae Gyu Park, Chae Gyu Park   +26 more
doaj   +1 more source

Inhibition of Cd83 Cell Surface Expression during Dendritic Cell Maturation by Interference with Nuclear Export of Cd83 mRNA [PDF]

The Journal of Experimental Medicine, 2000
Dendritic cells (DCs), nature's adjuvant, must mature to sensitize T cells. However, although the maturation process is essential, it is not yet fully understood at the molecular level. In this study, we investigated the course of expression of the unique hypusine-containing protein eukaryotic initiation factor 5A (eIF-5A), which is part of a ...
M, Kruse, O, Rosorius, F, Krätzer, D, Bevec, C, Kuhnt, A, Steinkasserer, G, Schuler, J, Hauber   +7 more
openaire   +2 more sources

Microsatellite unstable colorectal cancers are associated with increased CD1a- and CD83-positive dendritic cell infiltration

Biotechnology & Biotechnological Equipment, 2023
Microsatellite instability (MSI) is characterized by a highly immunogenic tumor phenotype and abundant lymphocytic infiltrates. The aim of this study was to investigate the association between four immunohistochemically determined classes of dendritic ...
Maya Gulubova, Elina Aleksandrova, Yovcho Yovchev, Dimitar Chonov, Petio Chilingirov, Tatyana Vlaykova   +5 more
doaj   +1 more source

Activation-induced expression of murine CD83 on T cells and identification of a specific CD83 ligand on murine B cells [PDF]

International Immunology, 2000
Human CD83 is a cell surface protein expressed predominantly by dendritic cells (DC) and lymphoid cells. So far, there exists no information on the function and distribution of mCD83. Here we demonstrate that mCD83 is moderately expressed on resting T cells and DC, but strongly increases in its expression on T cells following activation with antigenic ...
S O, Cramer, C, Trumpfheller, U, Mehlhoop, S, Moré, B, Fleischer, A, von Bonin   +5 more
openaire   +2 more sources

Unique Features and Distribution of the Chicken CD83+ Cell [PDF]

The Journal of Immunology, 2007
Abstract The central importance of dendritic cells (DC) in both innate and acquired immunity is well recognized in the mammalian immune system. By contrast DC have yet to be characterized in avian species despite the fact that avian species such as the chicken have a well-developed immune system.
Chris, Hansell, Xing Wu, Zhu, Heather, Brooks, Mark, Sheppard, Sam, Withanage, Duncan, Maskell, Ian, McConnell   +6 more
openaire   +2 more sources

The CD83 reporter mouse elucidates the activity of the CD83 promoter in B, T, and dendritic cell populations in vivo [PDF]

Proceedings of the National Academy of Sciences, 2008
CD83 is the major surface marker identifying mature dendritic cells (DCs). In this study, we report the generation of reporter mice expressing EGFP under the control of the CD83 promoter. We have used these mice to characterize CD83 expression by various immune system cell types both in vivo ...
Matthias, Lechmann, Naomi, Shuman, Andrew, Wakeham, Tak W, Mak   +3 more
openaire   +2 more sources