Results 11 to 20 of about 16,344 (174)
Reduced tolerogenic factor sCD83 in NMOSD and relapsing MOGAD: a potential new therapeutic pathway [PDF]
Frontiers in ImmunologyBackgroundNeuromyelitis optica spectrum disorders (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are autoimmune central nervous system disorders with poorly understood immune pathways. CD83 plays a crucial role in the
Ariel Rechtman +14 more
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Transdifferentiation of neutrophils facilitates the establishment of infection by Leishmania donovani parasites [PDF]
Infection and ImmunityNeutrophil transdifferentiation involves the acquisition of dendritic cell-like properties, challenging the traditional view of neutrophils being solely phagocytes. The presence of transdifferentiated neutrophils is established in Visceral Leishmaniasis,
Madhurima Roy +3 more
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Novel approaches to increase resistance to acute respiratory infections
RUDN Journal of Medicine, 2021 Relevance . Respiratory infections are the most common in the world. In order to prevent epidemics, there is a need to improve the strategies for organizing medical care and develop new approaches in order to increase the nonspecific resistance, mobilize
Svetlana V. Guryanova +5 more
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Journal of Innate Immunity, 2021 The mechanism of generation of antigen-specific regulatory T cells (Treg) is not fully understood yet. This study aimed to investigate the role of intestinal epithelial cell (IEC)-derived CD83 in the Treg generation in the intestine.
Yong Yu +8 more
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Nature Communications, 2023 Microglial activation during neuroinflammation is crucial for coordinating the immune response against neuronal tissue, and the initial response of microglia determines the severity of neuro-inflammatory diseases.
Pia Sinner +13 more
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Frontiers in Immunology, 2023 Excessive macrophage (Mφ) activation results in chronic inflammatory responses or autoimmune diseases. Therefore, identification of novel immune checkpoints on Mφ, which contribute to resolution of inflammation, is crucial for the development of new ...
Katrin Peckert-Maier +12 more
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Frontiers in Immunology, 2022 Antibodies targeting the activation marker CD83 can achieve immune suppression by targeting antigen-presenting mature dendritic cells (DC). This study investigated the immunosuppressive mechanisms of anti-CD83 antibody treatment in mice and tested its ...
Pablo A. Silveira +15 more
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CD83 polymorphisms and cervical cancer risk [PDF]
Gynecologic Oncology, 2009 Studies have suggested that polymorphisms in genes involved in immune recognition and antigen presentation are associated with cervical cancer risk. We sought to replicate a recent study which reported an association between specific SNPs on CD83 and cervical cancer and to further explore whether effects varied by age, clinical stage (in situ versus ...
Kelly J, Yu +4 more
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Immunological characteristics of dendritic cells marker CD83 in flounder (Paralichthys olivaceus)
Fish and Shellfish Immunology Reports, 2021 Dendritic cells (DCs) are the professional antigen presenting cells, which play important roles in regulating the immune response and tolerance. In mammals, CD83 is considered as a maturation marker for DCs, which is a type I membrane glycoprotein.
Fujing Dong +6 more
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Functional characterization of the HuR:CD83 mRNA interaction. [PDF]
PLoS ONE, 2011 Maturation of dendritic cells (DC) is characterized by expression of CD83, a surface protein that appears to be necessary for the effective activation of naïve T-cells and T-helper cells by DC. Lately it was shown that CD83 expression is regulated on the
Dorothea Pieper +5 more
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