Functional characterization of the HuR:CD83 mRNA interaction. [PDF]
PLoS ONE, 2011 Maturation of dendritic cells (DC) is characterized by expression of CD83, a surface protein that appears to be necessary for the effective activation of naïve T-cells and T-helper cells by DC. Lately it was shown that CD83 expression is regulated on the
Dorothea Pieper +5 more
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The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population [PDF]
The Journal of Immunology, 2016 Abstract CD83 is a member of the Ig gene superfamily, first identified in activated lymphocytes. Since then, CD83 has become an important marker for defining activated human dendritic cells (DC). Several potential CD83 mRNA isoforms have been described, including a soluble form detected in human serum, which may have an immunosuppressive
Xinsheng Ju +20 more
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Human Decidua Contains Potent Immunostimulatory CD83+ Dendritic Cells [PDF]
The American Journal of Pathology, 2000 Dendritic cells (DCs) are sentinel cells of the immune system important in initiating antigen-specific T-cell responses to microbial and transplantation antigens. DCs are particularly found in surface tissues such as skin and mucosa, where the organism is threatened by infectious agents.
U, Kämmerer +6 more
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Application of CD83 and HSF5 to Identify Antemortem and Postmortem Skin Burns
Fayixue Zazhi, 2021 ObjectiveTo explore the forensic application value of cluster of differentiation 83 （CD83） and heat shock transcription factor 5（HSF5） in identifying antemortem and postmortem skin burns.MethodsThrough reverse transcription real-time quantitative ...
ZHAO Long-rui +5 more
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Oscillation dynamics underlie functional switching of NF-κB for B-cell activation. [PDF]
, 2016 Transcription factor nuclear factor kappa B (NF-κB) shows cooperative switch-like activation followed by prolonged oscillatory nuclear translocation in response to extracellular stimuli.
Aihara, Kazuyuki +7 more
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Homologs of CD83 from Elasmobranch and Teleost Fish [PDF]
The Journal of Immunology, 2004 Abstract Dendritic cells are one of the most important cell types connecting innate and adaptive immunity, but very little is known about their evolutionary origins. To begin to study dendritic cells from lower vertebrates, we isolated and characterized CD83 from the nurse shark (Ginglymostoma cirratum (Gici)) and rainbow trout ...
Yuko, Ohta +7 more
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CD83 is a new potential biomarker and therapeutic target for Hodgkin lymphoma
Haematologica, 2018 Chemotherapy and hematopoietic stem cell transplantation are effective treatments for most Hodgkin lymphoma patients, however there remains a need for better tumor-specific target therapy in Hodgkin lymphoma patients with refractory or relapsed disease ...
Ziduo Li +21 more
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Anisakis pegreffii impacts differentiation and function of human dendritic cells [PDF]
, 2018 Human dendritic cells (DCs) show remarkably phenotypic changes when matured in presence of helminth-derived products. These modifications frequently elicited a polarization towards Th2 cells and regulatory T cells thus contributing to immunological ...
Allen +55 more
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Abnormal microglia and enhanced inflammation-related gene transcription in mice with conditional deletion of Ctcf in Camk2a-Cre-expressing neurons [PDF]
, 2017 CCCTC-binding factor (CTCF) is an 11 zinc finger DNA-binding domain protein that regulates gene expression by modifying 3D chromatin structure. Human mutations inCTCFcause intellectual disability and autistic features.
Barve, Ruteja A +9 more
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CD83 expression regulates antibody production in response to influenza A virus infection
Virology Journal, 2020 Background CD83 is known to regulate lymphocyte maturation, activation, homeostasis, and antibody response to immunization and infection. While CD83 has a major part in B cell function, its role in influenza A virus infection has not yet been ...
Madhav Akauliya +5 more
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