Results 131 to 140 of about 14,542 (144)
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Clinical Lymphoma Myeloma and Leukemia, 2021
Context and Objective CD83 is expressed on activated CD4+ T-cells, dendritic cells, and acute myeloid leukemia (AML), but its expression level on organ-specific normal tissue is not well investigated. A novel human CD83-targeted CAR T-cell has been developed and shown in preclinical work to treat and prevent graft-versus-host disease (GVHD) and confer
Tony Kurian +4 more
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Context and Objective CD83 is expressed on activated CD4+ T-cells, dendritic cells, and acute myeloid leukemia (AML), but its expression level on organ-specific normal tissue is not well investigated. A novel human CD83-targeted CAR T-cell has been developed and shown in preclinical work to treat and prevent graft-versus-host disease (GVHD) and confer
Tony Kurian +4 more
openaire +1 more source
Hodgkin’s cells express CD83, a dendritic cell lineage associated antigen
Pathology, 1997Hodgkin's cells (HC) are considered to be the malignant cells of Hodgkin's disease (HD), but despite extensive studies, no conclusive evidence has emerged regarding their non-malignant counterpart and the ontogeny of these cells remains controversial. The analysis of a possible dendritic cell (DC) origin of HC has been hampered to date by the lack of a
U R, Sorg +7 more
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Expression of Scophthalmus maximus CD83 correlates with bacterial infection and antigen stimulation
Fish & Shellfish Immunology, 2010CD83 is a transmembrane glycoprotein of the immunoglobulin (Ig) superfamily and a surface marker for fully matured dendritic cells (DCs) in humans and mice. In teleosts, DC-like cells and their molecular markers are largely unknown. In this report, we described the identification and expressional analysis of a CD83 homologue, SmCD83, from turbot ...
Yong-hua, Hu, Min, Zhang, Li, Sun
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Journal of Comparative Neurology, 2009
AbstractCells recruited by the innate immune response rely on surface‐expressed molecules in order to receive signals from the local environment and to perform phagocytosis, cell adhesion, and others processes linked to host defense. Hundreds of surface antigens designated through a cluster of differentiation (CD) number have been used to identify ...
Isaias, Glezer +2 more
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AbstractCells recruited by the innate immune response rely on surface‐expressed molecules in order to receive signals from the local environment and to perform phagocytosis, cell adhesion, and others processes linked to host defense. Hundreds of surface antigens designated through a cluster of differentiation (CD) number have been used to identify ...
Isaias, Glezer +2 more
openaire +2 more sources
Pathology - Research and Practice, 1999
In order to have insights into the abnormal immune regulation in primary biliary cirrhosis (PBC), different types of antigen presenting cells (APC) were localized immunohistochemically in liver specimens from 26 patients with PBC and compared with the distributions of APC from 11 and 10 patients with chronic hepatitis C (CH-C) and large bile duct ...
K, Tanimoto +3 more
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In order to have insights into the abnormal immune regulation in primary biliary cirrhosis (PBC), different types of antigen presenting cells (APC) were localized immunohistochemically in liver specimens from 26 patients with PBC and compared with the distributions of APC from 11 and 10 patients with chronic hepatitis C (CH-C) and large bile duct ...
K, Tanimoto +3 more
openaire +2 more sources
Blood, 2004
Abstract Following the engagement of the T cell receptor by HLA class I and antigenic peptide, naïve CD8+ T cells are primed to receive one or more costimulatory signals. Some of these signals, which are upregulated on and delivered by mature dendritic cells, include members of the immunoglobulin superfamily such as CD80 and CD83. Using
Naoto Hirano +2 more
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Abstract Following the engagement of the T cell receptor by HLA class I and antigenic peptide, naïve CD8+ T cells are primed to receive one or more costimulatory signals. Some of these signals, which are upregulated on and delivered by mature dendritic cells, include members of the immunoglobulin superfamily such as CD80 and CD83. Using
Naoto Hirano +2 more
openaire +1 more source
Hepatology Research, 2001
Although defective functions of peripheral blood or splenic antigen-presenting cells (APCs) are implicated in the pathogenesis of persistent infection in murine and human hepatitis B virus (HBV) and hepatitis C virus (HCV)-carriers, little is known regarding liver-infiltrating APCs in patients with chronic liver diseases.
K, Tanimoto +4 more
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Although defective functions of peripheral blood or splenic antigen-presenting cells (APCs) are implicated in the pathogenesis of persistent infection in murine and human hepatitis B virus (HBV) and hepatitis C virus (HCV)-carriers, little is known regarding liver-infiltrating APCs in patients with chronic liver diseases.
K, Tanimoto +4 more
openaire +2 more sources