Results 141 to 144 of about 14,542 (144)

Granulocyte macrophage colony-stimulating factor and interleukin 4 enhance the number and antigen-presenting activity of circulating CD14+ and CD83+ cells in cancer patients.

Cancer research, 2000
Antigen-presenting cells (APCs) are essential for stimulating antigen-specific immunity, including immunity against tumor cells. We hypothesized that systemic administration of granulocyte macrophage colony-stimulating factor (GM-CSF) and interleukin (IL)-4, which promote monocytes to differentiate into dendritic cells in vitro, might enhance the ...
M D, Roth, B J, Gitlitz, S M, Kiertscher, A N, Park, M, Mendenhall, N, Moldawer, R A, Figlin   +6 more
openaire   +1 more source

Induction of CD83+ CD14+ non-dendritic antigen-presenting cells by exposure of monocytes to IFN-alpha1

2008
ABSTRACT. Interferon (IFN)-α is a well known agent for treatment of viral and malignant diseases. It has several modes of actions, including direct influence on the immune system. We investigated IFN-α effects on peripheral blood mononuclear cells (PBMC) in terms of dendritic cell (DC) differentiation, as PBMC are exposed to high IFN-α levels during ...
GERLINI, GIANNI, MARIOTTI, GIULIA, CHIARUGI, ALBERTO, P. Di Gennaro, R. Caporale, PARENTI, ASTRID, L. Cavone, A. Tun Kyi, F. Prignano, R. Saccardi, L. Borgognoni, PIMPINELLI, NICOLA   +11 more
openaire   +1 more source

Interferon-α Exposure Increases The Number Of Cd83+ Antigen Presenting Cells In Peripheral Blood Mononuclear Cells

Melanoma Research, 2004
G. Gerlini, G. Mariotti, R. Caporale, F. Prignano, R. Saccardi, P. Cappugi, B. Giannotti, N. Pimpinelli   +7 more
openaire   +1 more source

Stimulating humoral response with antigen and CD83 protein of DNA: expression from a bacterium or a virus vector, for use as a recombinant vaccine adjuvant, for e.g. autoimmune disease, transplant rejection, allergy, asthma, etc. prevention

Vaccine, 1998
openaire   +1 more source