Results 161 to 170 of about 15,671 (193)
Reduced tolerogenic factor sCD83 in NMOSD and relapsing MOGAD: a potential new therapeutic pathway. [PDF]
Rechtman A +6 more
europepmc +1 more source
Decoding innate lymphoid cell heterogeneity and plasticity in colorectal cancer. [PDF]
Zhang S +11 more
europepmc +1 more source
Soluble CD14 and CD83 from Human Neonatal Antigen-Presenting Cells Are Inducible by Commensal Bacteria and Suppress Allergen-Induced Human Neonatal Th2 Differentiation [PDF]
ABSTRACTCD14 is expressed on the cell surface of various antigen-presenting cells, and CD83 is a maturation marker for dendritic cells (DC). CD14 and CD83 are also present as soluble proteins, and both have immunoregulatory functions. We examined whether neonatal cord blood monocytes or DC released soluble CD14 (sCD14) or sCD83 when exposed to the ...
Alexander Steinkasserer +2 more
exaly +5 more sources
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Expression of Scophthalmus maximus CD83 correlates with bacterial infection and antigen stimulation
Fish and Shellfish Immunology, 2010CD83 is a transmembrane glycoprotein of the immunoglobulin (Ig) superfamily and a surface marker for fully matured dendritic cells (DCs) in humans and mice. In teleosts, DC-like cells and their molecular markers are largely unknown. In this report, we described the identification and expressional analysis of a CD83 homologue, SmCD83, from turbot ...
Li Sun, Yonghua Hu
exaly +3 more sources
Hodgkin’s cells express CD83, a dendritic cell lineage associated antigen
Pathology, 1997Hodgkin's cells (HC) are considered to be the malignant cells of Hodgkin's disease (HD), but despite extensive studies, no conclusive evidence has emerged regarding their non-malignant counterpart and the ontogeny of these cells remains controversial. The analysis of a possible dendritic cell (DC) origin of HC has been hampered to date by the lack of a
Bridget Robinson +2 more
exaly +3 more sources
Following T-cell receptor and CD28 signaling, CD8+ T cells express a receptor for CD83, a molecule up-regulated on functionally mature dendritic cells. Although this expression pattern suggests that CD83 is involved in adaptive immunity, little is known about its function in the periphery, and the existence of its ligand on T cells is controversial. We
Gordon Freeman +2 more
exaly +4 more sources
Human CD83-targeted chimeric antigen receptor T cells prevent and treat graft-versus-host disease [PDF]
Graft-versus-host disease (GVHD) remains an important cause of morbidity and mortality after allogeneic hematopoietic cell transplantation (allo-HCT). For decades, GVHD prophylaxis has included calcineurin inhibitors, despite their incomplete efficacy and impairment of graft-versus-leukemia (GVL). Distinct from pharmacologic immune suppression, we have
Brian Betts +2 more
exaly +3 more sources
Clinical Lymphoma Myeloma and Leukemia, 2021
Context and Objective CD83 is expressed on activated CD4+ T-cells, dendritic cells, and acute myeloid leukemia (AML), but its expression level on organ-specific normal tissue is not well investigated. A novel human CD83-targeted CAR T-cell has been developed and shown in preclinical work to treat and prevent graft-versus-host disease (GVHD) and confer
Tony Kurian +4 more
openaire +1 more source
Context and Objective CD83 is expressed on activated CD4+ T-cells, dendritic cells, and acute myeloid leukemia (AML), but its expression level on organ-specific normal tissue is not well investigated. A novel human CD83-targeted CAR T-cell has been developed and shown in preclinical work to treat and prevent graft-versus-host disease (GVHD) and confer
Tony Kurian +4 more
openaire +1 more source
Pathology Research and Practice, 1999
In order to have insights into the abnormal immune regulation in primary biliary cirrhosis (PBC), different types of antigen presenting cells (APC) were localized immunohistochemically in liver specimens from 26 patients with PBC and compared with the distributions of APC from 11 and 10 patients with chronic hepatitis C (CH-C) and large bile duct ...
M Onji, S M Akbar
exaly +3 more sources
In order to have insights into the abnormal immune regulation in primary biliary cirrhosis (PBC), different types of antigen presenting cells (APC) were localized immunohistochemically in liver specimens from 26 patients with PBC and compared with the distributions of APC from 11 and 10 patients with chronic hepatitis C (CH-C) and large bile duct ...
M Onji, S M Akbar
exaly +3 more sources
Journal of Comparative Neurology, 2009
AbstractCells recruited by the innate immune response rely on surface‐expressed molecules in order to receive signals from the local environment and to perform phagocytosis, cell adhesion, and others processes linked to host defense. Hundreds of surface antigens designated through a cluster of differentiation (CD) number have been used to identify ...
Isaias, Glezer +2 more
openaire +2 more sources
AbstractCells recruited by the innate immune response rely on surface‐expressed molecules in order to receive signals from the local environment and to perform phagocytosis, cell adhesion, and others processes linked to host defense. Hundreds of surface antigens designated through a cluster of differentiation (CD) number have been used to identify ...
Isaias, Glezer +2 more
openaire +2 more sources

