Results 61 to 70 of about 378,605 (167)

LFA-1/ICAM-1 Interactions Between CD8⁺ and CD4⁺ T Cells Promote CD4⁺ Th1-Dominant Differentiation and CD8⁺ T Cell Cytotoxicity for Strong Antitumor Immunity After Cryo-Thermal Therapy

Cells
CD4+ T cells have been well-regarded as “helper” cells in activating the cytotoxicity of CD8+ T cells for effective tumor eradication, while few studies have focused on whether CD8+ T cells regulate CD4+ T cells.
Yichen Yao, Zelu Zhang, Shicheng Wang, Junjun Wang, Yuankai Hao, Ke Wang, Ping Liu   +6 more
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CD8+ T cells cure without killing [PDF]

Nature Reviews Immunology, 2019
Mala Maini describes a 1996 paper by Frank Chisari and colleagues that showed CD8+ T cells can exert potent antiviral efficacy against hepatitis B virus without lysing infected cells, through the production of antiviral cytokines.
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Activin A promoted the anti‐tumor effect of ActRIIA high CD8+ T cells in mouse hepatoma

Cancer Medicine
Background Activin A, a noteworthy member of the TGF‐β superfamily. Activin A can regulate the biological functions of various immune cells, such as macrophages, neutrophils, NK cells, etc.
Liangchang Hu, Yu Zhao, Xuguang Zhang, Chunhui Ma   +3 more
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Dynamic analysis of CD127 expression on memory CD8 T cells from patients with chronic hepatitis B during telbivudine treatment

Virology Journal, 2010
Background Accumulating evidence supports the theory that expression of CD127 on CD8 T cells during the process of antiviral immune response indicates a subset of effect CD8 T cells that successfully develop into fully protective memory.
Lv Guocai, Ying Linjung, Ma Wen-Jiang, Jin Xi, Zheng Lin, Li Lanjuan, Yang Yida   +6 more
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Genomic and transcriptional Profiling of tumor infiltrated CD8+ T cells revealed functional heterogeneity of antitumor immunity in hepatocellular carcinoma

OncoImmunology, 2019
As key players in HCC antitumor response, the functions of tumor infiltrated CD8+ T cells are significantly affected by surrounding microenvironment. A detailed profiling of their genomic and transcriptional changes could provide valuable insights for ...
Zhenli Li, Geng Chen, Zhixiong Cai, Xiuqing Dong, Liman Qiu, Haipo Xu, Yongyi Zeng, Xiaolong Liu, Jingfeng Liu   +8 more
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Characterization of CD8+ T cell subsets in male and female non-obese diabetic mice

陆军军医大学学报
Objective To compare and analyze the differences in CD8+ naive, effector, memory, exhausted and regulatory T cells in order to investigate the impact of gender on the differentiation fate of CD8+ T cells in the context of type 1 diabetes (T1D) based on ...
YANG Shushu, LIU Dong, LI Jie
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Deficiencies of Inducible Costimulator (ICOS) During Chronic Infection with Toxoplasma gondii Upregulate the CD28-Dependent Cytotoxicity of CD8⁺ T Cells and Their Effector Function Against Tissue Cysts of the Parasite

Cells
We recently identified that the cerebral mRNA expression of inducible costimulator (ICOS) and its ligand, ICOSL, both significantly increase during the elimination of Toxoplasma gondii cysts from the brains of infected mice by the perforin-mediated ...
Rajesh Mani, Kanal E. Balu, Yasuhiro Suzuki   +2 more
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Pre-existing intratumoral stem-like CD8+ T cells drive radiotherapy-induced tumor immunity

Cell Reports
Summary: CD8+ T cells are crucial for both spontaneous and therapy-induced restriction of tumor progression. Although many patients with cancer undergo radiotherapy, the precise effect of this genotoxic treatment on tumor-associated CD8+ T cells is ...
Hakan Köksal, Michael Herbst, Paulo Perreira, Marc Nater, Nicola Regli, Cheïma Boudjeniba, Nese Erdem Borgoni, Virginia Cecconi, Maries van den Broek   +8 more
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RNA-based co-transfer of human CD8αβ with WT1-specific TCRαβ redirects tumor recognition by CD4 and γδ T-cells towards MHC class I-restricted WT1 epitopes and boosts CD8 T-cell responses with or without CD3 mRNA

Experimental Hematology & Oncology
We evaluated the redirection of CD4, γδ and CD8 T-cells towards the Wilms’ tumor protein (WT1) tumor-associated antigen, using a major histocompatibility complex (MHC) class I-restricted WT1-specific T-cell receptor (TCR) introduced via RNA-based ...
Diana Campillo-Davo, Donovan Flumens, Zwi N. Berneman, Fumihiro Fujiki, Gils Roex, Maarten Versteven, Heleen H. Van Acker, Viggo F. I. Van Tendeloo, Haruo Sugiyama, Sébastien Anguille, Eva Lion   +10 more
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CD8+ T suppressor cell

Citation: 'CD8+ T suppressor cell' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12977 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
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