Results 91 to 100 of about 42,229 (197)
Cellular Physiology and Biochemistry, 2015 Background/Aims: Ursodeoxycholic acid, which in vivo is rapidly converted into its taurine conjugate, is frequently used for the treatment of cholestatic liver disease.
Annika Sommerfeld +2 more
doaj +1 more source
CD95 Structure, Aggregation and Cell Signaling
Frontiers in Cell and Developmental Biology, 2020 CD95 is a pre-ligand-associated transmembrane (TM) receptor. The interaction with its ligand CD95L brings to a next level its aggregation and triggers different signaling pathways, leading to cell motility, differentiation or cell death.
Nicolas Levoin +2 more
doaj +1 more source
Impaired bone marrow homing of cytokine-activated CD34+ cells in the NOD/SCID model [PDF]
, 2004 The reduced engraftment potential of hematopoietic stem/progenitor cells (HSPCs) after exposure to cytokines may be related to the impaired homing ability of actively cycling cells. We tested this hypothesis by quantifying the short-term horning of human
Ahmed, F +8 more
core
Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding, and fission. [PDF]
, 2005 Galectins have emerged as a novel family of immunoregulatory proteins implicated in T cell homeostasis. Recent studies showed that galectin-1 (Gal-1) plays a key role in tumor-immune escape by killing antitumor effector T cells.
Ascione, Barbara +7 more
core +1 more source
Advanced Science, Volume 13, Issue 7, 3 February 2026.Current SARS‐CoV‐2 vaccines generate short‐lived, strain‐specific immunity. A polymeric TLR7 agonist nanoparticle (TLR7‐NP) adjuvant enhances lymph node targeting and promotes early and sustained germinal center responses toward conserved S2 epitopes of the spike protein.
Sijin Huang +12 more
wiley +1 more source
Muir-Torre syndrome - Treatment with isotretinoin and interferon alpha-2a can prevent tumour development [PDF]
, 2000 Muir-Torre syndrome is a genodermatosis in which multiple internal malignancies are associated with cutaneous sebaceous tumours and kerato-acanthomas. A 57-year-old man presented with multiple sebaceous tumours, kerato-acanthomas, verrucous carcinoma of ...
Burgdorf, Walter H. C. +3 more
core +1 more source
Mucosal‐Associated Invariant T Cells in Rheumatic Diseases
Arthritis &Rheumatology, Volume 78, Issue 2, Page 287-297, February 2026.Mucosal‐associated invariant T (MAIT) cells are innate‐like T cells defined by their semi‐invariant T cell receptor and restriction by the major histocompatibility complex class I–related molecule (MR1). These cells are primarily activated by microbial‐derived metabolites presented by MR1 or by cytokines.
Manon Lesturgie‐Talarek +7 more
wiley +1 more source
Cell death pathways as therapeutic targets in rhabdomyosarcoma [PDF]
, 2012 Resistance of rhabdomyosarcoma to current therapies remains one of the key issues in pediatric oncology. Since the success of most cytotoxic therapies in the treatment of cancer, for example, chemotherapy, depends on intact signaling pathways that ...
Fulda, Simone
core +1 more source
SN Shock Evolution in the Circumstellar Medium surrounding SN 1987A
, 2007 We study the structure of the circumstellar medium surrounding SN 1987A in the equatorial plane. Furthermore, we study the evolution of the SN shock within this medium during the first 25 years, and the resulting hard X-ray and radio emission from the ...
Kurt Weiler +2 more
core +1 more source
The asymmetric radio remnant of SN 1987A [PDF]
, 1996 We present seven years of radio observations of SN 1987A made with the Australia Telescope Compact Array. At 1.4, 2.4, 4.8 and 8.6 GHz, the flux density of the radio remnant has increased monotonically since emission was redetected 1200 days after the ...
A. K. Tzioumis +30 more
core +2 more sources