Results 41 to 50 of about 24,240 (208)
The dual role of the CD95 and CD95L signaling pathway in glioblastoma
Frontiers in Immunology, 2022 Binding of CD95, a cell surface death receptor, to its homologous ligand CD95L, transduces a cascade of downstream signals leading to apoptosis crucial for immune homeostasis and immune surveillance.
Yanrui Zhang +7 more
doaj +1 more source
Advanced Science, EarlyView.Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song +5 more
wiley +1 more source
Apoptotic markers in CD34-positive cells in acute leukemias
Клиническая онкогематология, 2013 Objective. To evaluate expression of Bcl-2, Bax, p53, CD95, and ACE on CD34+ cells of peripheral blood and bone marrow during induction chemotherapy in the patients with newly diagnosed acute leukemia. Materials and methods.
Ye. N. Parovichnikova +7 more
doaj +1 more source
IL-7 promotes CD95-induced apoptosis in B cells via the IFN-γ/STAT1 pathway. [PDF]
PLoS ONE, 2011 Interleukin-7 (IL-7) concentrations are increased in the blood of CD4+ T cell depleted individuals, including HIV-1 infected patients. High IL-7 levels might stimulate T cell activation and, as we have shown earlier, IL-7 can prime resting T cell to CD95
Stefano Sammicheli +7 more
doaj +1 more source
Fas/CD95 Signaling Pathway in Damage-Associated Molecular Pattern (DAMP)-Sensing Receptors
Cells, 2022 Study of the initial steps of the CD95-mediated signaling pathways is a field of intense research and a long list of actors has been described in the literature.
Gael Galli +4 more
doaj +1 more source
Advanced Science, EarlyView.As engineered nanomaterials gain prominence in cancer imaging and therapy, understanding their impact on tumor progression becomes increasingly critical. We demonstrate that gold and silica‐coated gold nanomaterials can either suppress or enhance breast cancer metastasis through distinct tumor microenvironment interactions, while identifying ...
Kiana Buttiens +11 more
wiley +1 more source
CD95 Rapidly Clusters in Cells of Diverse Origins [PDF]
, 2003 We have shown that CD95-mediated cell death requires a clustering of the receptor in distinct sphingolipid-rich domains of the cell membrane (Grassmé et al., 2000, Cremesti et al., 2000).
Fanzo, Jessica C. +11 more
core +1 more source
Сучасна педіатрія: УкраїнаThe aim of this study was to investigate immunological and apoptotic markers in children with congenital heart defects (CHDs) in order to assess their pathogenetic role and diagnostic significance. Material and methods.
L.V. Mammadova +3 more
doaj +1 more source
Вавиловский журнал генетики и селекции, 2016 CD95 is one of the best studied members of the death receptor family. Activation of CD95 leads to the induction of the cell death programme, apoptosis, via formation of the death-inducing signaling complex (DISC).
N. V. Ivanisenko +3 more
doaj +1 more source
Advanced Science, EarlyView.Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li +9 more
wiley +1 more source