Results 21 to 30 of about 24,240 (208)

CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling [PDF]

, 2009
CD95 is a multifunctional receptor that induces cell death or proliferation depending on the signal, cell type, and cellular context. Here, we describe a thus far unknown function of CD95 as a silencer of T cell activation.
Lindquist, Jonathan, Strauss, Gudrun, Lindquist, Jonathan A., Arhel, Nathalie, Nathalie Arhel, Tobias L. Haas, Edward Felder, Fulda, Simone, Haas, Tobias L., Henning Walczak, Felder, Edward, Kirchhoff, Frank, Gudrun Strauss, Sabine Karl, Simone Fulda, Walczak, Henning, Karl, Sabine, Frank Kirchhoff, Klaus-Michael Debatin, Debatin, Klaus-Michael, Jonathan A. Lindquist, Haas, Tobias   +21 more
core   +1 more source

CD95 and truncated CD95(1–210)-expressing PS120 clones.

, 2023
All PS120 cells are reconstituted with wild type NHE1 (see Materials and Methods). (A) Upper panel: analysis of the CD95 expression at the surface of the indicated PS120 clones stably expressing either the CD95 wild type or its death domain truncated ...
Eric Selva (216754), Sophie Daburon (216759), Cécile Contin-Bordes (216761), Jacques Le Seyec (216763), Paul Hofman (103032), Sébastien Tauzin (216750), Laurent Counillon (216766), Jean-François Moreau (11510), Benjamin Chaigne-Delalande (216753), Thomas Ducret (216765), Nadine Khadra (216756), Pierre Vacher (216767), Patrick Legembre (216769), Patrick Blanco (11512)   +13 more
core   +1 more source

Markers of apoptosis in patients with type 1 diabetes mellitus at the onset of the disease

Сахарный диабет, 2009
Aim. This work was to study activation markers of apoptosis (CD95, CD95L) on peripheral blood lymphocytes of patients with type 1 diabetes mellitus (DM1) at the onset of the disease. Materials and methods.
Elena Vladimirovna Pekareva, Tatiana Vasil'evna Nikonova, Vera Anatol'evna Gorelysheva, Yana Stanislavovna Zvereva, Svetlana Mikhailovna Stepanova, Sergey Alexandrovich Prokof'ev, Olga Mikhailovna Smirnova   +6 more
doaj   +1 more source

CD95-tyrosine Nitration Inhibits Hyperosmotic and CD95 Ligand-induced CD95 Activation in Rat Hepatocytes [PDF]

Journal of Biological Chemistry, 2004
Epidermal growth factor receptor-dependent CD95-tyrosine phosphorylation was recently identified as an early step in apoptosis induction via the CD95 system (Reinehr, R., Schliess, F., and Häussinger, D. (2003) FASEB J. 17, 731-733). The effect of peroxynitrite (ONOO(-)) on modulation of the hyperosmotic and CD95 ligand (CD95L)-induced CD95 activation ...
Roland, Reinehr, Boris, Görg, Andrea, Höngen, Dieter, Häussinger   +3 more
openaire   +2 more sources

CD95 ligand induces senescence in mismatch repair-deficient human colon cancer via chronic caspase-mediated induction of DNA damage [PDF]

, 2017
CD95 is best known for its ability to induce apoptosis via a well-characterized pathway involving caspase-mediated proteolytic events. However, in apoptosis-resistant cell lines of diverse cancer types stimulation of CD95 primarily has pro-tumorigenic ...
Inne HMBorel Rinkes, Raats, DAE, Laoukili, Jamila, Jamila Laoukili, Borel Rinkes, IHM, Nicola Frenkel, Frenkel, Nicola, Danielle A Raats, Susanne J van Schelven, Onno Kranenburg, Kranenburg, OW, van Schelven, Susanne J   +11 more
core   +1 more source

Erratum: The role of CD95 and CD95 ligand in cancer [PDF]

Cell Death & Differentiation, 2015
Correction to: Cell Death and Differentiation (2015) 22, 549–559; doi:10.1038/cdd.2015.3; published online 6 February 2015 Since the publication of this article the authors have noted that they have inadvertently failed to list an important paper in the field in Table 2. This work (Kleber et al.) has now been added to the revised Table 2 shown below.
M E Peter, A Hadji, A E Murmann, S Brockway, W Putzbach, A Pattanayak, P Ceppi   +6 more
openaire   +1 more source

Irradiation-Induced Pneumonitis Mediated by the CD95/CD95-Ligand System [PDF]

JNCI: Journal of the National Cancer Institute, 2006
Pneumonitis is a dose-limiting side effect of radiotherapy. However, the underlying mechanisms of irradiation-induced pneumonitis are unclear. Several observations suggest that the CD95/CD95-ligand (CD95L) system is involved in this process. Therefore, we examined the development of pneumonitis in CD95- and CD95L-deficient and wild-type mice after ...
Frank, Heinzelmann, Verena, Jendrossek, Kirsten, Lauber, Kerstin, Nowak, Therese, Eldh, Ruzica, Boras, Rene, Handrick, Marco, Henkel, Christian, Martin, Stefan, Uhlig, David, Köhler, Holger K, Eltzschig, Manfred, Wehrmann, Wilfried, Budach, Claus, Belka   +14 more
openaire   +2 more sources

Immunoexpression of CD95 in chronic gastritis and gastric mucosa-associated lymphomas [PDF]

Brazilian Journal of Medical and Biological Research, 2004
CD95 (Fas/APO-1)-mediated apoptosis plays an important role in immunological regulation and is related to the pathogenesis of autoimmune diseases.
Vassallo J., Godoy Jr. C.E., Godoy C.E., Chagas C.A., Metze K., Trevisan M.A.S.   +5 more
doaj   +3 more sources

A genetic IFN/STAT1/FAS axis determines CD4 T stem cell memory levels and apoptosis in healthy controls and Adult T-cell Leukemia patients

OncoImmunology, 2018
Adult T-cell leukemia (ATL) is an aggressive, chemotherapy-resistant CD4+CD25+ leukemia caused by HTLV-1 infection, which usually develops in a minority of patients several decades after infection. IFN + AZT combination therapy has shown clinical benefit
Ricardo Khouri, Gilvanéia Silva-Santos, Tim Dierckx, Soraya Maria Menezes, Daniele Decanine, Kristof Theys, Aline Clara Silva, Lourdes Farré, Achiléa Bittencourt, Massimo Mangino, Mario Roederer, Anne-Mieke Vandamme, Johan Van Weyenbergh   +12 more
doaj   +1 more source

ROLE OF CD95 AND DR3 RECEPTORS IN NA VE T-LYMPHOCYTES APOPTOSIS IN CHILDREN WITH INFECTIOUS MONONUCLEOSIS DURING CONVALESCENCE

Инфекция и иммунитет, 2017
Infectious mononucleosis is a widespread disease caused by certain members of Herpesviridae family. Acute infectious mononucleosis develops predominantly in children and is accompanied by an increase of the number of circulating naive CD4+ and naive CD8+
E. N. Filatova, E. V. Anisenkova, N. B. Presnyakova, E. A. Kulova, O. V. Utkin   +4 more
doaj   +1 more source