Results 131 to 140 of about 531,349 (289)

Isolation and expression of a gene specifying a cdc2-like protein kinase from the human malaria parasite Plasmodium falciparum.

European Journal of Biochemistry, 1994
A partially redundant oligonucleotide based on conserved protein sequences of cdk and cdc2-like proteins was used to isolate from genomic libraries of Plasmodium falciparum fragments of chromosome XIII carrying a 288-residue open-reading frame encoding a
P. Ross-Macdonald, R. Graeser, B. Kappes, R. Franklin, D. Williamson   +4 more
semanticscholar   +1 more source

Complex coordination of cell plasticity by a PGC-1α-controlled transcriptional network in skeletal muscle [PDF]

, 2015
Skeletal muscle cells exhibit an enormous plastic capacity in order to adapt to external stimuli. Even though our overall understanding of the molecular mechanisms that underlie phenotypic changes in skeletal muscle cells remains poor, several factors ...
Agrawal, Aitchison, Altschul, Andersson, Blows, Blows, Bonduriansky, Brooks, Chenoweth, Chenoweth, Chung, Connallon, Coyne, Dallerac, Darwin, Doerge, Eyre-Walker, Fang, Ferreira, Ferveur, Fiumera, Frentiu, Gibbs, Gosden, Haldane, Hereford, Hine, Hine, Hine, Howard, Howard, Johnston, Kennington, Kingsolver, Kistler, Labeur, Lande, Long, Magwire, Mousseau, Park, Rako, Reinhart, Ritchie, Roff, Rundle, Sall, Siller, Swanson, Wagner, Weeks, Wilkinson, Zhang   +52 more
core   +4 more sources

Tau protein kinase II has a similar characteristic to cdc2 kinase for phosphorylating neurofilament proteins

Journal of Biological Chemistry, 1993
Tau protein kinase II purified from a bovine brain tau protein fraction (Ishiguro, K., Takamatsu, M., Tomizawa, K., Omori, A., Takahashi, M., Arioka, M., Uchida, T., and Imahori, K. (1992) J. Biol. Chem. 267, 10897-10901) was shown to have a similar substrate specificity to cdc2 kinase in that both phosphorylate neurofilament (NF) proteins. Tau protein
Takeo Kishimoto, T. Okano, K. Ishiguro, Eiichi Okumura, Shin-ichi Hisanaga, T. Uchida   +5 more
openaire   +3 more sources

Role of C5b-9 and RGC-32 in Cancer

Frontiers in Immunology, 2019
The complement system represents an effective arsenal of innate immunity as well as an interface between innate and adaptive immunity. Activation of the complement system culminates with the assembly of the C5b-9 terminal complement complex on cell ...
Sonia I. Vlaicu, Sonia I. Vlaicu, Alexandru Tatomir, Violeta Rus, Horea Rus   +4 more
doaj   +1 more source

Quantitative and functional post-translational modification proteomics reveals that TREPH1 plays a role in plant thigmomorphogenesis [PDF]

, 2018
Plants can sense both intracellular and extracellular mechanical forces and can respond through morphological changes. The signaling components responsible for mechanotransduction of the touch response are largely unknown. Here, we performed a high-throughput SILIA (stable isotope labeling in Arabidopsis)-based quantitative phosphoproteomics analysis ...
arxiv   +1 more source

On the Synthesis of [1,3]Azaphospholo[4,5‐f]quino(xa)lines and 2,3‐Dihydro‐[1,3]azaphospholo[4,5‐f]quino(xa)line 1‐oxides

European Journal of Organic Chemistry, Volume 28, Issue 17, May 21, 2025.
Syntheses of quinoline and quinoxaline derivatives fused with phosphacycles were developed from commercially available quinolin‐6‐amine and quinoxalin‐6‐amine. Abstract Despite their potential in areas such as medicinal chemistry and organic materials, scaffolds in which quinoline and quinoxaline are fused to phosphacycles such as 1,3‐oxaphosphole, 1,3‐
Mohamed Ali Dridi, Mohamed Hasyeoui, Frédéric Lassagne, William Erb, Charline Piroud, Thomas Robert, Stéphane Bach, Ali Samarat, Soufiane Touil, Florence Mongin   +9 more
wiley   +1 more source

Mutations In RAD27 Define A Potential Link Between G₁ Cyclins And DNA Replication [PDF]

, 1995
The yeast Saccharomyces cerevisiae has three G1 cyclin (CLN) genes with overlapping functions. To analyze the functions of the various CLN genes, we examined mutations that result in lethality in conjunction with loss of cln1 and cln2.
Cross, Frederick R., , \u2778, Vallen, Elizabeth Ann   +1 more
core   +1 more source

The Rad4TopBP1 ATR-Activation domain functions in G1/S phase in a chromatin-dependent manner [PDF]

, 2012
DNA damage checkpoint activation can be subdivided in two steps: initial activation and signal amplification. The events distinguishing these two phases and their genetic determinants remain obscure.
Carr, Antony, Caspari, Thomas, Chahwan, Charly, Garcia, Valerie, Lin, Su-Jiun, Miyabe, Izumi, Morishita, Takashi, Schmidt, Ulrike, Wardlaw, Christopher Paul   +8 more
core   +4 more sources

Activation of p34cdc2 kinase by cyclin A [PDF]

, 1991
Functional clam cyclin A and B proteins have been produced using a baculovirus expression system. Both cyclin A and B can induce meiosis I and meiosis II in Xenopus in the absence of protein synthesis.
Gabrielli, B. G., Li, R. S., Maller, J. L., Piwnicaworms, H., Roy, L. M., Swenson, K. I., Walker, D. H.   +6 more
core   +1 more source

CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle.

Proceedings of the National Academy of Sciences of the United States of America, 1992
Critical cell cycle transitions are controlled by the coordinate actions of the p34cdc2 protein kinase and its regulatory subunits, cyclins. Recently we identified another human p34 homolog, cyclin-dependent kinase 2 (CDK2) by complementation of a cdc28 ...
S. Elledge, R. Richman, F. Hall, R. Williams, N. Lodgson, J. Harper   +5 more
semanticscholar   +1 more source