Results 121 to 130 of about 6,022 (190)

The PTK7 and ROR2 Protein Receptors Interact in the Vertebrate WNT/Planar Cell Polarity (PCP) Pathway *

open access: yes, 2015
International audienceBackground: The planar cell polarity pathway plays important roles in morphogenetic processes. Results: PTK7 and ROR2 form a heterodimeric complex and bind to WNT5A, promoting JNK phosphorylation and regulating expression of ...
Borg, Jean-Paul   +7 more
core   +4 more sources

The GCN2 kinase is required for activating autophagy in response to indispensable amino acid deficiencies [PDF]

open access: yes, 2016
ORGANIZING COMMITTEEChairs: Didier Attaix - Lydie Combaret - Daniel TaillandierDaniel Béchet - Agnès Claustre - Cécile Coudy-Gandilhon - Christiane Deval - Gérard Donadille - Cécile PolgeSCIENTIFIC COMMITTEEDidier Attaix - Lydie Combaret - Alfred L ...
Averous, Julien   +10 more
core   +1 more source

Targeting protein-protein interactions in drug discovery: Modulators approved or in clinical trials for cancer treatment

open access: yesPharmacological Research
Protein-protein interactions (PPIs) form complex cellular networks fundamental to many key biological processes, including signal transduction, cell proliferation and DNA repair.
Cristina Camps-Fajol   +3 more
doaj   +1 more source

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