Results 141 to 150 of about 3,509 (196)

Beyond Folding: Expanding the Functional Landscape of Hsp90 Chaperone Machinery in Health and Disease. [PDF]

Int J Mol Sci
Singh MK, Ranbhise JS, Fu M, Ju S, Han S, Yun HR, Choe W, Kim SS, Kang I.   +8 more
europepmc   +1 more source

Alphappimi: a comprehensive deep learning framework for predicting PPI-modulator interactions. [PDF]

J Cheminform
Liu D, Song T, Wang S, Li X, Han P, Wang J, Wang S.   +6 more
europepmc   +1 more source

Advances in the structures, mechanisms and targeting of molecular chaperones. [PDF]

Signal Transduct Target Ther
Gu J, He Y, He C, Zhang Q, Huang Q, Bai S, Wang R, You Q, Wang L.   +8 more
europepmc   +1 more source

The role of the FKBP51-Hsp90 complex in Alzheimer's disease: An emerging new drug target. [PDF]

Cell Stress Chaperones
Jeanne X, Török Z, Vigh L, Prodromou C.   +3 more
europepmc   +1 more source

CDK4/6 Inhibitors for Breast Cancer Therapy-A Review of Clinical Trials, Structural and Computational Approaches. [PDF]

Pharmaceuticals (Basel)
Avdičević A, Lešnik S, Bren U, Čavka L.   +3 more
europepmc   +1 more source

Targeting HSP90 in cancer: advances in the development of inhibitors, mechanisms of action, and therapeutic applications. [PDF]

Mol Cancer
Wang X, Ni R, Wang X, Li X.
europepmc   +1 more source

Repurposing Ilaprazole as a PP5 TPR Domain Binder with Modulatory Effects on MAPK Signaling. [PDF]

ACS Med Chem Lett
He Y, Gu J, Hua L, Zhai D, Huang Q, Pei J, You Q, Zhang Q, Wang L.   +8 more
europepmc   +1 more source

Interface-aware molecular generative framework for protein-protein interaction modulators. [PDF]

J Cheminform
Wang J, Mao J, Li C, Xiang H, Wang X, Wang S, Wang Z, Chen Y, Li Y, No KT, Song T, Zeng X.   +11 more
europepmc   +1 more source

Combining cryo-electron microscopy (cryo-EM) with orthogonal solution state methods to define the molecular basis of the phosphoprotein phosphatase family regulation and substrate specificity. [PDF]

Curr Opin Struct Biol
Peti W, Padi SKR, Page R.
europepmc   +1 more source

The known unknowns of the Hsp90 chaperone. [PDF]

Elife
Silbermann LM, Vermeer B, Schmid S, Tych K.   +3 more
europepmc   +1 more source