In most eukaryotes, Cdc37 is an essential chaperone, transiently associating with newly synthesised protein kinases in order to promote their stabilisation and activation.
Andrew Truman (5282144) +5 more
core
NIH [HL070079, HL062311, HL080111, F31AG032163]Rationale: p38 is an important stress activated protein kinase involved in gene regulation, proliferation, differentiation, and cell death regulation in heart.
Ota, A. +5 more
core
The plasma protein profile of left ventricular diastolic function. [PDF]
Eerola E, Lind L, Malinovschi A.
europepmc +1 more source
Dissecting the Cdc37 cochaperone code: Functional roles in chaperone-mediated stress adaptation. [PDF]
Mitchem MM +4 more
europepmc +1 more source
Evolution of Hsp90 targeting: From stress biology to clinical translation. [PDF]
Zarguan I +3 more
europepmc +1 more source
Beyond Inhibition: Rebalancing the Hsp90 Chaperone Network as a Therapeutic Strategy for Alzheimer's Disease. [PDF]
Tang Z +8 more
europepmc +1 more source
An Exploratory Study of Heat Shock Protein Changes in Women with Unexplained Infertility. [PDF]
Alhalwachi Z +3 more
europepmc +1 more source
The dihydropyridine LA1011 modulates multiple Hsp90-co-chaperone interactions relevant to Alzheimer's disease. [PDF]
Jeanne X +7 more
europepmc +1 more source
AI-enabled single-cell dissection of the palmitoylation landscape identifies a multicellular prognostic program in gastric cancer. [PDF]
Xu J +9 more
europepmc +1 more source
Langerhans cell histiocytosis: molecular mechanisms underlying pathogenesis and emerging targeted therapeutics. [PDF]
Li Q, Hu J.
europepmc +1 more source

