The GCN2 kinase is required for activating autophagy in response to indispensable amino acid deficiencies [PDF]
, 2016 ORGANIZING COMMITTEEChairs: Didier Attaix - Lydie Combaret - Daniel TaillandierDaniel Béchet - Agnès Claustre - Cécile Coudy-Gandilhon - Christiane Deval - Gérard Donadille - Cécile PolgeSCIENTIFIC COMMITTEEDidier Attaix - Lydie Combaret - Alfred L ...
Averous, Julien +10 more
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Pharmacological ResearchProtein-protein interactions (PPIs) form complex cellular networks fundamental to many key biological processes, including signal transduction, cell proliferation and DNA repair.
Cristina Camps-Fajol +3 more
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Cyclin B1/CDK1-regulated mitochondrial bioenergetics in cell cycle progression and tumor resistance. [PDF]
, 2019 A mammalian cell houses two genomes located separately in the nucleus and mitochondria. During evolution, communications and adaptations between these two genomes occur extensively to achieve and sustain homeostasis for cellular functions and ...
Jiang, Nian +3 more
core
Protein network analysis reveals selectively vulnerable regions and biological processes in FTD [PDF]
, 2018 Karch, Celeste M. +2 more
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Targeting the protein-protein interaction between the CDC37 cochaperone and client kinases by an allosteric RAF dimer breaker. [PDF]
J Biol ChemYu A +5 more
europepmc +1 more source
Tumor suppressor Tsc1 is a new Hsp90 co‐chaperone that facilitates folding of kinase and non‐kinase clients [PDF]
, 2017 et al, +3 more
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Dissecting the Cdc37 cochaperone code: Functional roles in chaperone-mediated stress adaptation. [PDF]
J Biol ChemMitchem MM +4 more
europepmc +1 more source
The dihydropyridine LA1011 modulates multiple Hsp90-co-chaperone interactions relevant to Alzheimer's disease. [PDF]
Cell Stress ChaperonesJeanne X +7 more
europepmc +1 more source