Results 111 to 120 of about 1,377 (129)

Study of the cell biological role of Lowe Syndrome protein OCRL1

, 2009
Oculocerebrorenal syndrome of Lowe (OCRL) is caused by mutations in a phosphatidylinositol 5-phosphatase, OCRL1, and is believed to lead to an elevation of its preferred substrate, PI(4,5)P2.
Grieve, A.G.
core  

Imidazoline receptor antisera-selected protein: a unique modulator of neuronal differentiation.

, 2008
The imidazoline I1 receptor (I1-R) is a novel receptor found primarily in the brain and nervous tissue where it modulates neurotransmission. It is named for its high affinity for compounds with an imidazoline structure such as the anti-hypertensive drugs,
Dehle, Francis Christian
core  

The function of Toc34 and its regulation [PDF]

, 2003
Jelic, Marko
core  

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Gene expression of the small GTP-binding proteins RhoA, RhoB, Rac1, and Cdc42 in adult rat brain

Molecular Brain Research, 1997
GTPases of the Rho subfamily, i.e. Rho, Rac and Cdc42, are molecular switches in various signaling pathways. Best characterized are their functions in the regulation of the actin cytoskeleton. In neuronal cell lines they are involved in the mechanisms leading to synapse formation and plasticity.
Olenik, Claudia, Barth, Holger, Just, Ingo, Aktories, Klaus, Meyer, Dieter K.   +4 more
openaire   +3 more sources

Distribution of the small molecular weight GTP-binding proteins Rac1, Cdc42, RhoA and RhoB in the developing chick retina

Journal of Neurocytology, 2002
Immunohistochemistry was used to determine the distribution of Rac1, Cdc42, RhoA and RhoB GTPases during development of the chick retina. All proteins appear as early as embryonic day 5 (E5) in cells of the vitreal margin, E7-8 in cells of the inner third of the inner nuclear layer and E9-10 in photoreceptors.
Andréa Silveira, Santos-Bredariol, Marinilce Fagundes, Santos, Dânia Emi, Hamassaki-Britto   +2 more
openaire   +2 more sources

Regulation of Cdc42 protein turnover modulates the filamentous growth MAPK pathway

Journal of Cell Biology, 2022
, Paul J Cullen, Gonzalez BEATRIZ
exaly  

Corequirement of Specific Phosphoinositides and Small GTP-binding Protein Cdc42 in Inducing Actin Assembly in Xenopus Egg Extracts

Journal of Cell Biology, 1998
Lewis C Cantley, Paul A Janmey, Marc W Kirschner   +2 more
exaly  

Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitor

Small GTPases, 2016
Rory Henderson, Thallapuranam Krishnaswamy Suresh Kumar, Colin D Heyes   +2 more
exaly  

Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation

Oncogene, 2001
Wataru Ikeda, Hiroyuki Nakanishi, Yoshimi Takai   +2 more
exaly  

Structure of Cdc42 in complex with the GTPase-binding domain of the ‘Wiskott–Aldrich syndrome’ protein

Nature, 1999
Ananya Majumdar, Ouathek Ouerfelli, Katherine A Siminovitch   +2 more
exaly