Results 91 to 100 of about 1,377 (129)
The protein GMAP-210 (Golgi Microtubule Associated Protein of 210 kDa) is a long coiled-coil protein, which localises to the Golgi apparatus. It is part of the loosely defined protein group of the golgins, which are involved in establishing the Golgi ...
Egerer, Johannes
core
Cdc42-GTP is elevated in CLN3-null MBECs.
(A) Cdc42-GTP activity was quantified from primary (WT and Cln3−/−) or immortalized (Cln3R and Cln3−/−) MBEC lysates. (B) Total Cdc42 protein levels were quantified by western blot, expressed as band intensity normalized to the actin loading control. (C)
Mark A. Stamnes (558606) +4 more
core +1 more source
The cGMP-dependent protein kinase II Is an inhibitory modulator of the hyperpolarization-activated HCN2 channel [PDF]
Opening of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels is facilitated by direct binding of cyclic nucleotides to a cyclic nucleotide-binding domain (CNBD) in the C-terminus. Here, we show for the first time that in the HCN2 channel
Biel Martin +14 more
core +1 more source
Certain small GTP-binding proteins control the enzymatic activity of a family of closely related serine-threonine kinases known as mitogen-activated protein kinases (MAPKs). In turn, these MAPKs, such as p44(mapk) and p42(mapk), referred to herein as MAPKs, and stress-activated protein kinases, also termed c-Jun N-terminal kinases (JNKs), phosphorylate
H, Teramoto +5 more
openaire +1 more source
Molecular cloning and expression of a small GTP-binding protein of the Rop family from mung bean
The Rho family, a group of small GTP-binding proteins, consists of Rho, Rac and Cdc42 subfamilies in animals and yeasts, and modulates many cellular processes related to the actin cytoskeleton.
이동희
core +1 more source
Cell polarization occurs along a single axis that is generally determined by a spatial cue. Cells of the budding yeast exhibit a characteristic pattern of budding, which depends on cell-type-specific cortical markers, reflecting a genetic programming for
Mid Eum Lee (380103) +9 more
core +1 more source
A systems and molecular analysis of G protein-mediated signalling [PDF]
The ability of cells to respond correctly to signals from their microenvironment is an essential prerequisite of life. Many external signals are detected through G protein-coupled receptor (GPCR) signalling pathways, which control all aspects of ...
Croft, Wayne D.
core
G protein-coupled receptor kinase 2 (GRK2) phosphorylates and desensitizes activated G protein-coupled receptors (GPCRs). Here, we identify ezrin as a novel non-GPCR substrate of GRK2. GRK2 phosphorylates glutathione S-transferase (GST)-ezrin, but not an
Pitcher, JA, Cant, SH
core
We have examined the subcellular distribution of Rho-related small GTP-binding proteins in the kidney. RhoA, CDC42, and Rac1 small GTP-binding proteins were found to be expressed at high levels in rat outer kidney cortex.
R. Beliveau, D. Boivin
core +1 more source

