Results 91 to 100 of about 4,215,470 (170)

Folding transitions during assembly of the eukaryotic mRNA cap-binding complex. [PDF]

, 2006
The cap-binding protein eIF4E is the first in a chain of translation initiation factors that recruit 40S ribosomal subunits to the 5' end of eukaryotic mRNA. During cap-dependent translation, this protein binds to the 5'-terminal m(7)Gppp cap of the mRNA,
von der Haar, Tobias, Ptushkina, Marina, Wagner, Gerhard, McCarthy, John E G, Moerke, Nathan, Oku, Yuko, McCarthy, John E. G., Mccarthy, John, Gross, John D.   +8 more
core   +1 more source

alpha 2-chimaerin, a Cdc42/Rac1 regulator, is selectively expressed in the rat embryonic nervous system and is involved in neuritogenesis in N1E-115 neuroblastoma cells [PDF]

, 2001
Neuronal differentiation involves Rac and Cdc42 GTPases. alpha -Chimaerin, a Rac/Cdc42 regulator, occurs as alpha 1- and alternatively spliced Src homology 2 (SH2) domain-containing alpha 2-isoforms. alpha 2-chimaerin mRNA was highly expressed in the rat
Christine Hall, Giovanna Ferrari, Nansi Cann, Teo, M., Clinton Monfries, Michael, G.J., Cann, N., Louis Lim, Ferrari, G., Jacobs, T., Mabel Teo, Hall, C., Tom Jacobs, Lim, L., Gregory J. Michael, Monfries, C.   +15 more
core   +1 more source

Regulation of the leading edge motility by PI (4,5)P2-dependent lipid microdomains [PDF]

, 2005
The lipid second messenger PI(4,5)P2 modulates actin dynamics, and its local accumulation at plasmalemmal microdomains (rafts) might mediate regulation of protrusive motility.
Golub, Tamara
core   +1 more source

Cdc42 induces EGF receptor protein accumulation and promotes EGF receptor nuclear transport and cellular transformation [PDF]

, 2014
Cdc42 is a Ras-related small GTP-binding protein. A previous study has shown that Cdc42 binding to the γ subunit of the coatomer protein complex (γCOP) is essential for Cdc42-regulated cellular transformation, but the molecular mechanism involved is not ...
Cheng, Jin-Quan, Wang, Jian-Bin, Li, Yong, Han, Tian-Yu, Xiao-Yu Wang, Jin-Quan Cheng, Jian-Bin Wang, Han, Xiao-Jian, Tian-Yu Han, Gan, Ming-Xi, Wei-Hua Zhan, Xiao-Jian Han, Ming-Xi Gan, Zhan, Wei-Hua, Wang, Xiao-Yu, Yong Li   +15 more
core   +1 more source

An HflX-type GTPase from Sulfolobus solfataricus binds to the 50S ribosomal subunit in all nucleotide-bound states [PDF]

, 2011
HflX GTPases are found in all three domains of life, Bacteria, Archaea, and Eukaryotes. HflX from Escherichia coli has been shown to bind to the 50S ribosomal subunit in a nucleotide-dependent manner and this interaction strongly stimulates its GTPase ...
Fabian Blombach, J. Van Der Oost, Daan C. Swarts, John van der Oost, Londei, P., LONDEI, Paola, Christodoulou, John, John Christodoulou, Dario Benelli, D. c. Swarts, Lisa D. Cabrita, Launay, H., BENELLI, DARIO, H. Launay, Benelli, D., L. d. Cabrita, Violeta Zorraquino, Zorraquino, V., Cabrita, L.D., V. Zorraquino, Oost, J., van der, F. Blombach, J. Christodoulou, Helene Launay, Paola Londei, van der Oost, J., Blombach, F., Swarts, D.C.   +27 more
core   +1 more source

Cloning and characterisation of genes determining pod morphology in pea [PDF]

, 1994
Genes expressed in developing pea pods were isolated as cDNAs by differential screening techniques. The cDNAs were characterised by DNA sequencing and expression studies were used to investigate the role of isolated cDNAs in pod development.
Drew, J.E, Drew, Janice Elizabeth
core  

Structure and function of bacterial dynamin-like proteins [PDF]

, 2012
Membrane dynamics are essential for numerous cellular processes in eukaryotic and prokaryotic cells. In eukaryotic cells, membrane fusion and fission are often catalyzed by large GTPases of the dynamin protein family. These proteins couple GTP hydrolysis
Bramkamp, Marc
core   +1 more source

Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family.

The Journal of biological chemistry, 1996
Certain small GTP-binding proteins control the enzymatic activity of a family of closely related serine-threonine kinases known as mitogen-activated protein kinases (MAPKs). In turn, these MAPKs, such as p44(mapk) and p42(mapk), referred to herein as MAPKs, and stress-activated protein kinases, also termed c-Jun N-terminal kinases (JNKs), phosphorylate
H, Teramoto, O A, Coso, H, Miyata, T, Igishi, T, Miki, J S, Gutkind   +5 more
openaire   +1 more source

G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton [PDF]

, 2005
G protein-coupled receptor kinase 2 (GRK2) phosphorylates and desensitizes activated G protein-coupled receptors (GPCRs). Here, we identify ezrin as a novel non-GPCR substrate of GRK2. GRK2 phosphorylates glutathione S-transferase (GST)-ezrin, but not an
Pitcher, JA, Cant, SH
core  

Editorial: Rho family GTPases and their effectors in neuronal survival and neurodegeneration

Frontiers in Cellular Neuroscience, 2023
Daniel A. Linseman, Qun Lu
doaj   +1 more source