Results 21 to 30 of about 72,294 (253)

Expression of cyclin-dependent kinases and their clinical significance with immune infiltrates could predict prognosis in colorectal cancer

open access: yesBiotechnology Reports, 2021
Introduction: Colorectal cancer (CRC) is one of the most cancer-related mortalities worldwide and remains a major public health issue. Despite several attempts to develop promising therapies for CRC, its survival rate decreases with metastasis.
Adewale Oluwaseun Fadaka   +5 more
doaj   +1 more source

The regulation of CDK activity by cyclins [PDF]

open access: yes, 2021
In eukaryotes, the two major cell cycle events of DNA replication and chromosome segregation are directed by Cyclin Dependent Kinases (CDKs) in combination with G1/S cyclins (S-CDK) and G2/M cyclins (M-CDK), respectively.
Basu, Souradeep
core   +1 more source

Integrated analysis of microRNA expression in tears of Kazakh patients with climatic droplet keratopathy in Xinjiang, China

open access: yesHeliyon, 2023
Climatic droplet keratopathy (CDK) is a corneal diseases, which is characterized by increased oil-like deposits on the anterior elastic lamina and anterior stromal layer. Severe CDK can even cause blindness, with no specific available treatment. Besides.
Zhixiang Hua   +8 more
doaj   +1 more source

Aaptamine attenuates the proliferation and progression of non-small cell lung carcinoma

open access: yesPharmaceutical Biology, 2020
Context Aaptamine is a potent ocean-derived non-traditional drug candidate against human cancers. However, the underlying molecular mechanisms governing aaptamine-mediated repression of lung cancer cells remain largely undefined. Objective To examine the
Kaikai Gong   +8 more
doaj   +1 more source

Cyclin E and Cdk2 control GLD-1, the mitosis/meiosis decision, and germline stem cells in Caenorhabditis elegans. [PDF]

open access: yesPLoS Genetics, 2011
Coordination of the cell cycle with developmental events is crucial for generation of tissues during development and their maintenance in adults. Defects in that coordination can shift the balance of cell fates with devastating clinical effects.
Johan Jeong   +2 more
doaj   +1 more source

cdk/cdk: CDK 2.4

open access: yes, 2021
$ git shortlog -s -n $v1..$v2 278 John Mayfield 13 Egon Willighagen 11 Uli Fechner 5 Mark Williamson 3 Valentyn Kolesnikov 2 MehmetAzizYirik 2 Marco Foscato 1 dependabot[bot] 1 Tim Dudgeon 1 Otto Brinkhaus 1 Christoph ...
John Mayfield   +29 more
core   +1 more source

Proteogenomic characterization of cholangiocarcinoma

open access: yesHepatology, EarlyView., 2022
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng   +18 more
wiley   +1 more source

New Insights on Slavic God Volosъ / Velesъ from a Vedic Perspective
Novi uvidi o staroslovenskom bogu Volosu / Velesu iz vedske perspektive

open access: yesStudia Mythologica Slavica, 2019
In 1973, Ivanov and Toporov developed an attempted reconstruction of the presumably central theme of ancient Slavic mythology, viz. the cosmic battle between the thunder-god Perunъ and his adversary Volosъ the cattle god, modelled after the analogous ...
Milorad Ivanković
doaj   +1 more source

Genome-wide identification of cyclin-dependent kinase (CDK) genes affecting adipocyte differentiation in cattle

open access: yesBMC Genomics, 2021
Background Cyclin-dependent kinases (CDKs) are protein kinases regulating important cellular processes such as cell cycle and transcription. Many CDK genes also play a critical role during adipogenic differentiation, but the role of CDK gene family in ...
Cuili Pan   +8 more
doaj   +1 more source

CDK-5 colocalizes with RPM-1 LD in neuronal soma.

open access: yes, 2022
A) Schematic showing ALM mechanosensory neuron and region imaged for axon termination site (blue) and soma (red). B) CDK-5::mScarlet CRISPR is present in the soma of ALM neurons (bracket) visualized using transgenic GFP expressed in mechanosensory ...
Brock Grill (561446)   +5 more
core   +1 more source

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