Results 131 to 140 of about 46,551 (257)
Andrology, EarlyView.ABSTRACT Background Macrozoospermia is a rare form of teratozoospermia characterized by tetraploids, large‐headed spermatozoa with multiple flagella, usually caused by bi‐allelic AURKC mutations. The etiology of atypical phenotypes with a lower proportion of large headed spermatozoa and single flagella however often remains unresolved.
Aurore Perrin +14 more
wiley +1 more source
Validation of Cxbladder Triage Plus in Australian patients with haematuria: the AUSSIE study
BJU International, EarlyView.Objectives To assess the clinical validity of Cxbladder Triage Plus (Pacific Edge Ltd., Dunedin, New Zealand), a non‐invasive urinary biomarker assay, for urothelial carcinoma (UC) risk stratification compared with standard‐of‐care evaluation (cystoscopy) in patients presenting with visible or non‐visible haematuria (VH or NVH) in routine practice in ...
Varun Buhariwalla +8 more
wiley +1 more source
CDK1-loaded extracellular vesicles promote cell cycle to reverse impaired wound healing in diabetic obese mice [PDF]
Small extracellular vesicles (sEVs) mediate intercellular signaling to coordinate the proliferation of cell types that promote re-epithelialization of skin following injury.
Park, Dong Jun +5 more
core +1 more source
Wee1 kinase differentially regulates maize CDKA2;1a and CDKB1;1
The FEBS Journal, EarlyView.In eukaryotes, Wee1 kinase inhibits the kinase activity of CDK/Cyc complexes through phosphorylation of a conserved residue in the CDK moiety. Wee1 is also present in plants, but has been scarcely studied. We have studied maize Wee1 regulation of CDKA/CycD2;2a or CDKB/CycD2;2a complexes.
Mingyar N. López‐Hernández +4 more
wiley +1 more source
A guide to transcriptional cyclin‐dependent kinases in cancer
The FEBS Journal, EarlyView.Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin +2 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney +4 more
wiley +1 more source
Journal of Cell Communication and Signaling, Volume 20, Issue 4, December 2026.CAMKK2 inhibition induces extensive phosphoproteomic remodeling associated with cell cycle regulation, RNA processing, and kinase signaling networks in gastric cancer. Integrated systems‐level analyses identified dysregulated CDK, SRPK, MAPK, and AKT signaling pathways underlying malignant phenotypes and highlighted CAMKK2 as a potential therapeutic ...
Mohd. Altaf Najar +2 more
wiley +1 more source
Glia, Volume 74, Issue 11, November 2026.Zebrafish Müller glia are heterogeneous in the early larval retina. Zebrafish Müller glia subtypes define a spatial axis of retinoic acid metabolism. Neuron‐associated glial programs identified in Zebrafish Müller glia are evolutionarily conserved in mammals. ABSTRACT Müller glia are instrumental macroglia of the vertebrate retina, once thought to be a
Samuel S. Storey +3 more
wiley +1 more source
Cdk1: A kinase with changing substrate specificity [PDF]
Cell Cycle, 2011 Mardo, Kõivomägi, Mart, Loog
openaire +2 more sources
Immunostaining of Ki-67 and CDK1.
, 2019 Immunohistochemical analysis of Ki-67 and CDK1 expression in aortic dissection (n = 5) and control tissue samples (n = 5). A: Strong Ki-67 expression on aortic dissection tissue. B: Weak Ki-67 expression on control tissue.
Weitie Wang (5381612) +9 more
core +1 more source