Results 141 to 150 of about 28,778 (201)

CDK5 Inhibits Synphilin-1 Ubiquitination and Basal Mitophagy: Implications for Parkinson's Disease. [PDF]

Int J Mol Sci
Savyon M, Avraham E, Shah AK, Hamza H, Szargel R, Abd Elghani F, Farhoud M, Toren-Hershkoviz M, Pavoncello N, Zaer S, Bandopadhyay R, Safory H, Engelender S.   +12 more
europepmc   +1 more source

CDK5 wt Allele [PDF]

, 2020
openaire   +1 more source

The CDK inhibitor Roscovitine enhances the therapeutic efficacy of anti-PD-1 in non-small cell lung cancer. [PDF]

Front Oncol
Diaz-Montero CM, Holvey-Bates EG, Rayman PA, Parker Y, Lindner DJ, Stark GR, De S.   +6 more
europepmc   +1 more source

Brain region-specific dopamine receptor changes and astrocyte activation influence tau pathology through CDK5 in Alzheimer's disease models. [PDF]

J Alzheimers Dis
Singh S, Kumar U.
europepmc   +1 more source

CDK5-mediated hyperphosphorylation of Tau217 impairs neuronal synaptic structure and exacerbates cognitive impairment in Alzheimer's disease. [PDF]

Transl Psychiatry
Fu K, Lin N, Xu Y, Huang E, He R, Wu Z, Qu D, Chen X, Huang T.   +8 more
europepmc   +1 more source

Manipulating mitochondrial reactive oxygen species alters survival in unexpected ways in a Drosophila Cdk5 model of neurodegeneration

Biology Open
Andrew P. K. Wodrich, Brent T. Harris, Edward Giniger   +2 more
doaj   +1 more source

Aggregation Characteristics of Tau Phosphorylated by Various Kinases as Observed by Quantum Dot Fluorescence Imaging. [PDF]

Int J Mol Sci
Ishibashi E, Araya K, Nakamura K, Shimamori K, Uwai K, Kuragano M, Tokuraku K.   +6 more
europepmc   +1 more source

Activity-dependent phosphorylation of CDYL by CDK5 regulates fear memory in mice. [PDF]

Transl Psychiatry
Lyu NY, Xie GG, Hu ZW, Lyu TJ, Qin R, Chen L, Wang Y.   +6 more
europepmc   +1 more source

miR-432 Exacerbates Obesity-Induced Dysregulation of Glucose and Lipid Homeostasis. [PDF]

Diabetes
Wang C, Hou Y, Zhang M, Wang J, Chu X, Liang M, Sun C, Xie J, Zhang J, Wang CY.   +9 more
europepmc   +1 more source

Discovery of small molecules and a druggable groove that regulate DNA binding and release of the AP-1 transcription factor ΔFOSB. [PDF]

J Biol Chem
McNeme S, Yim YY, Kumar A, Li Y, Hughes B, St Romain CP, Aglyamova G, Chen J, Nguyen ND, Fan S, Stephens GS, Zhao WN, Kruzshak S, Estill M, Brener C, Tofani S, Kumar A, Chen EP, Takatka N, Robison AJ, Chen H, Powell RT, Haggarty SJ, Stephan C, Nestler EJ, Chin J, Machius M, Zhou J, Rudenko G.   +28 more
europepmc   +1 more source