Results 111 to 120 of about 6,157 (185)

SauCas9-based cell cycle-dependent genome editing via AAV delivery. [PDF]

Mol Ther Adv
Matsugi E, Kishi K, Kishi A, Nagase K, Nigorikawa K, Nomura W.   +5 more
europepmc   +1 more source

CDK12 mediates the inhibition effect of mechanical unloading on osteoblast proliferation by regulating RNAPII transcription activation. [PDF]

Bone Joint Res
Hu L, Zhong W, Wang L, Liang S, Jia Y, Wu Z, Shen J, Sun J, Qian A.   +8 more
europepmc   +1 more source

DNA damage induces Cdt1 proteolysis in fission yeast through a pathway dependent

, 2006
Cdt1 is an essential protein required for licensing of replication origins. Here, we show that in Schizosaccharomyces pombe, Cdt1 is proteolysed in M and G1 phases in response to DNA damage and that this mechanism seems to be conserved from yeast to ...
Erik Boye, Emma Ralph, Stephen E Kearsey
core  

Replication origin flexibility: a tool to mitigate the hazards of excess replication. [PDF]

Trends Genet
Fu H, Redon CE, Brenner HM, Ack MR, Aladjem MI.   +4 more
europepmc   +1 more source

Functional domains of the Xenopus replication licensing factor Cdt1. Nucleic Acids Res

, 2005
During late mitosis and early G1, replication origins are licensed for subsequent replication by loading heterohexamers of the mini-chromosome mainten-ance proteins (Mcm2-7).
Andrew Ferenbach, Anatoliy Li, J. Julian Blow, Marta Brito-martins   +3 more
core  

Physiological re-replication during human stem cell differentiation. [PDF]

Cell Death Discov
Minet M, Beganovic A, Rishik S, Michaeli E, Yildiz D, Schmartz GP, Schwarz PE, Schäfer M, Tänzer T, Cucchiarini M, Ludwig N, Keller A, Meese E, Fischer U.   +13 more
europepmc   +1 more source

Molecular impacts of Meier-Gorlin syndrome mutations on human origin licensing. [PDF]

J Biol Chem
Yang R, Hunker O, Kim J, Bleichert F.
europepmc   +1 more source

The chromosomal instability associated gene C2orf76 exerts dual roles in colorectal cancer through pyroptosis and chemotherapy response. [PDF]

Front Oncol
Zhang L, Song Z, Zhang P, Jiang Y, Xiang Y, Wang Z, Ding Y, Rui B, Zhou Y, Jiang J, Cao S, Liu X.   +11 more
europepmc   +1 more source

License to Replicate: Mechanisms of Licensing Eukaryotic Origins for DNA Replication. [PDF]

Bioessays
Frisbie V, Bleichert F.
europepmc   +1 more source

Combined Inhibition of Wee1 and Checkpoint Kinases Synergistically Provokes S-Phase Progression and Mitotic Entry, and Promotes Cell Death Under Heat Stress. [PDF]

Genes Cells
Muratani T, Takeya H, Ishibashi R, Kurakawa T, Ikushiro SI, Nagai Y, Tabuchi Y, Kondo T, Furusawa Y.   +8 more
europepmc   +1 more source