Results 61 to 70 of about 5,745 (188)
Acta Medica Iranica, 2022 Meier-Gorlin syndrome (MGS) is a rare autosomal recessive disorder with homozygous or heterozygous mutations in one of the five following genes (ORC1, ORC4, ORC6, CDT1, and CDC6).
Shahin Koomanaee +6 more
doaj +1 more source
Advanced Science, Volume 13, Issue 26, 8 May 2026.BiSCALE: A pathology‐driven deep learning framework for multi‐scale gene expression prediction from whole‐slide images. It accurately infers bulk and near‐cellular spot‐level expression, links predictions to clinical phenotypes, identifies disease‐associated niches, and enables applications in risk stratification and cell‐identity annotation, providing
Hailong Zheng +8 more
wiley +1 more source
Ectopic expression of Cdt1 lowers the G1 arrest response.
, 2015 A. Extra copy of Cdt1 expressing cells have more MCM2-7 on the chromatin. Control (293) and Cdt1-3NLSmyc expressing HEK293 cells (Cdt1) were arrested in M phase and released with (M-UV) or without [(-)UV] UV irradiation (60 J/m2).
Takeshi Maeda (304955) +6 more
core +1 more source
Cdt1 stabilizes kinetochore–microtubule attachments via an Aurora B kinase–dependent mechanism [PDF]
, 2018 Robust kinetochore-microtubule (kMT) attachment is critical for accurate chromosome segregation. G2/M-specific depletion of human Cdt1 that localizes to kinetochores in an Ndc80 complex-dependent manner leads to abnormal kMT attachments and mitotic ...
Aussie Suzuki +11 more
core +1 more source
Zone Matcher: A climate‐based web application for deployment and assisted migration of forest trees
Ecosphere, Volume 17, Issue 4, April 2026.Abstract Populations of forest trees are generally adapted to the climates they inhabit. The farther trees are moved from their local climates, the more long‐term growth and survival tend to decrease. Current tree deployment and assisted migration rely on “climate distance thresholds” (CDTs), which are climatic distances beyond which tree performance ...
Tal J. Shalev +6 more
wiley +1 more source
BMC Cancer, 2008 Background The tongue squamous cell carcinomas (SCCs) are characterized by high mitotic activity, and early detection is desirable. Overexpression of the DNA replication-initiation proteins has been associated with dysplasia and malignancy.
Tu Zheng +6 more
doaj +1 more source
Contrasting quiescent G0 phase with mitotic cell cycling in the mouse immune system. [PDF]
PLoS ONE, 2013 A transgenic mouse line expressing Fucci (fluorescent ubiquitination-based cell-cycle indicator) probes allows us to monitor the cell cycle in the hematopoietic system.
Michio Tomura +7 more
doaj +1 more source
Fiber Reinforcement of Soft Spider Silk Hydrogels
Macromolecular Rapid Communications, Volume 47, Issue 7, 3 April 2026.Along the development of matrices for biomedical applications, precise tuning of the biomaterial to interact with specific cell types/tissues is essential. The fabrication of fiber mesh‐reinforced soft hydrogels made of recombinant spider silk proteins allows for the adjustment of mechanical properties and hydrogel porosity, leading to improved cell ...
Christina Heinritz, Thomas Scheibel
wiley +1 more source
Caffeine inhibits UV-induced rapid degradation of Cdt1.
, 2013 A. Asynchronously growing HeLa cells treated with caffeine (+, 10 mM) or not (−) were UV-irradiated (50 J/m2) and collected for Western blotting with Cdt1 and Cdt2. For Cdt2 blotting, samples were run on Phos-tag gels.
Takeshi Maeda (304955) +7 more
core +1 more source
Jnk2 effects on tumor development, genetic instability and replicative stress in an oncogene-driven mouse mammary tumor model. [PDF]
PLoS ONE, 2010 Oncogenes induce cell proliferation leading to replicative stress, DNA damage and genomic instability. A wide variety of cellular stresses activate c-Jun N-terminal kinase (JNK) proteins, but few studies have directly addressed the roles of JNK isoforms ...
Peila Chen +8 more
doaj +1 more source