Results 91 to 100 of about 114,770 (357)
Advanced Science, EarlyView.In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo +8 more
wiley +1 more source
A Simple Microbiome in the European Common Cuttlefish, Sepia officinalis. [PDF]
, 2019 The European common cuttlefish, Sepia officinalis, is used extensively in biological and biomedical research, yet its microbiome remains poorly characterized.
Abbo, Lisa +9 more
core +1 more source
Lauric acid is an inhibitor of Clostridium difficile growth in vitro and reduces inflammation in a mouse infection model [PDF]
, 2018 Indexación: Scopus.Clostridium difficile is a Gram-positive, spore-forming anaerobic human gastrointestinal pathogen. C. difficile infection (CDI) is a major health concern worldwide, with symptoms ranging from diarrhea to pseudomembranous colitis, toxic
Ababouch +71 more
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Journal of the American Medical Association, 1911 History. —Mr. B., a retired farmer, aged 62, presented himself at my office complaining of pain in the abdomen, and alternate attacks of constipation and diarrhea. The personal and family history was negative. The patient had always been well, with the exception of having been confined to his bed for a few days, some years ago, on account of having ...
openaire +1 more source
Advanced Science, EarlyView.A bioactive hydrogel incorporating Chlorella vulgaris and paeoniflorin within a carboxymethyl chitosan/sodium alginate matrix cross‐linked with genipin is developed for inflammatory bowel disease therapy. The hydrogel exhibits gastric stability and intestine‐responsive release.
Jing Lu +8 more
wiley +1 more source
Infection-generated electric field in gut epithelium drives bidirectional migration of macrophages. [PDF]
, 2019 Many bacterial pathogens hijack macrophages to egress from the port of entry to the lymphatic drainage and/or bloodstream, causing dissemination of life-threatening infections. However, the underlying mechanisms are not well understood.
Ferreira, Fernando +14 more
core +2 more sources
Epidermoid Cyst of the Cecum [PDF]
Annals of Coloproctology, 2015 An epidermoid cyst of the cecum is extremely rare; only eight cases have been reported in the literature. A 63-year-old woman was admitted to Kyung Hee University Medical Center with a colonic mass that had been discovered incidentally during a regular health check-up. The radiographic impression was that this mass was a gastrointestinal stromal tumor.
Park, Jae-Young +3 more
openaire +2 more sources
Advanced Science, EarlyView.Engineered mesoporous silica nanoparticles (Silicasomes) enable systemic delivery of the STING agonist ADU‐S100, overcoming the instability and toxicity that limit cyclic dinucleotides to local administration. By enhancing tumor accumulation, activating systemic antitumor immunity, and remodeling the tumor immune microenvironment, these nanoparticles ...
Wenjing Zhou +10 more
wiley +1 more source
Poultry Science: This study evaluated the alleviative effect of curcumin (CUR) on the diquat (DQ)-induced cecal injury in broilers. A total of 320 one-day-old Cobb broilers were selected and randomly divided into 4 treatments, namely control, DQ, CUR 100, and CUR150 ...
Fengyang Wu +6 more
doaj +1 more source
Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity. [PDF]
, 2020 Death due to sepsis remains a persistent threat to critically ill patients confined to the intensive care unit and is characterized by colonization with multi-drug-resistant healthcare-associated pathogens.
Alverdy, John C +24 more
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