Results 21 to 30 of about 7,241 (141)

Hendra virus influences meningoencephalitis-based mortality: A comprehensive review [PDF]

Journal of Zoonotic Diseases
This article looks at the zoonotic paramyxovirus known as Hendra virus (HeV) was initially discovered in Hendra, Queensland, which is located in Australia, in 1994.
Margret Chandira Rajappa, Nagasubramanian Venkatasubramaniam , Harish Kesavan , Jagadhish Balaji , Mohan Kumar Saravanan , Hari Rajamanikam   +5 more
doaj   +2 more sources

Trafficking and Activation of Henipavirus, Parahenipavirus, and Henipa-like Virus Fusion Proteins [PDF]

Viruses
Henipaviruses are emerging zoonotic viruses that have caused deadly outbreaks in humans and livestock across several regions of the world. The fusion (F) protein of henipaviruses plays a critical role in viral entry into host cells and represents a key ...
Chanakha K. Navaratnarajah, Roberto Cattaneo   +1 more
doaj   +2 more sources

Development and Immunogenic Evaluation of a Recombinant Vesicular Stomatitis Virus Expressing Nipah Virus F and G Glycoproteins

Viruses
Nipah virus (NiV) is a highly pathogenic bat-borne zoonotic pathogen that poses a significant threat to human and animal health, with fatality rates exceeding 70% in some outbreaks.
Huijuan Guo, Renqiang Liu, Dan Pan, Yijing Dang, Shuhuai Meng, Dan Shan, Xijun Wang, Jinying Ge, Zhigao Bu, Zhiyuan Wen   +9 more
doaj   +2 more sources

A phase 1 trial of the safety, tolerability and biological effects of intravenous Enadenotucirev, a novel oncolytic virus, in combination with chemoradiotherapy in locally advanced rectal cancer (CEDAR) [PDF]

Radiation Oncology, 2020
Background Chemoradiotherapy remains the standard of care for locally advanced rectal cancer. Efforts to intensify treatment and increase response rates have yet to yield practice changing results due to increased toxicity and/or absence of increased ...
Séan M. O’Cathail, Steven Davis, Jane Holmes, Richard Brown, Kerry Fisher, Leonard Seymour, Richard Adams, James Good, David Sebag-Montefiore, Tim Maughan, Maria A. Hawkins   +10 more
doaj   +8 more sources

Development and evaluation of a quadruple real-time fluorescence-based quantitative reverse transcription polymerase chain reaction assay for detecting Langya, Mojiang, Nipah, and Cedar viruses

Biosafety and Health
The emerging viruses within the genus Henipavirus in the family Paramyxoviridae pose a great threat to public biosafety. To develop a quadruple real-time fluorescence-based quantitative reverse transcription polymerase chain reaction (qRT-PCR) assay is ...
Wenjun He, Tian Ma, Yalan Wang, Weifang Han, Jun Liu, Wenwen Lei, Le Zhang, Guizhen Wu   +7 more
doaj   +2 more sources

Hendra Virus Infection Dynamics in the Grey-Headed Flying Fox (Pteropus poliocephalus) at the Southern-Most Extent of Its Range: Further Evidence This Species Does Not Readily Transmit the Virus to Horses.

PLoS ONE, 2016
Hendra virus (HeV) is an important emergent virus in Australia known to infect horses and humans in certain regions of the east coast. Whilst pteropid bats ("flying foxes") are considered the natural reservoir of HeV, which of the four mainland species ...
A L Burroughs, P A Durr, V Boyd, K Graham, J R White, S Todd, J Barr, I Smith, G Baverstock, J Meers, G Crameri, L-F Wang   +11 more
doaj   +2 more sources

Cell Extracts Derived from Cypress and Cedar Show Antiviral Activity against Enveloped Viruses

Microorganisms
The antiviral efficacy of cell-extracts (CEs) derived from cypress (Chamaecyparis obtusa (Siebold & Zucc.) Endl., C. obtusa) and cedar (Cryptomeria japonica (Thunb. ex. L.) D.Don, C.
Takashi Furukawa, Ayumu Inagaki, Takeshi Hatta, Suzuha Moroishi, Katsuki Kawanishi, Yuki Itoh, Shotaro Maehana, Mohan Amarasiri, Kazunari Sei   +8 more
doaj   +2 more sources

An in vivo BSL-2 model for henipavirus infection based on bioluminescence imaging of recombinant Cedar virus replication in mice. [PDF]

Front Chem Biol
Henipaviruses are enveloped single-stranded, negative-sense RNA viruses of the paramyxovirus family. Two henipaviruses, Nipah virus and Hendra virus, cause a systemic respiratory and/or neurological disease in humans and ten additional species of mammals, with a high fatality rate. Because of their highly pathogenic nature, Nipah virus and Hendra virus
Huaman C, Clouse C, Rader M, Yan L, Bai S, Gunn BM, Amaya M, Laing ED, Broder CC, Schaefer BC.   +9 more
europepmc   +3 more sources

Nipah and Hendra Viruses: Deadly Zoonotic Paramyxoviruses with the Potential to Cause the Next Pandemic

Pathogens, 2022
Nipah and Hendra viruses are deadly zoonotic paramyxoviruses with a case fatality rate of upto 75%. The viruses belong to the genus henipavirus in the family Paramyxoviridae, a family of negative-sense single-stranded RNA viruses.
Sabahat Gazal, Neelesh Sharma, Sundus Gazal, Mehak Tikoo, Deep Shikha, Gulzar Ahmed Badroo, Mohd Rashid, Sung-Jin Lee   +7 more
doaj   +1 more source

Distinct Cell Transcriptomic Landscapes Upon Henipavirus Infections

Frontiers in Microbiology, 2020
Hendra virus (HeV) and Cedar virus (CedV) are henipaviruses, which fall into the Paramyxoviridae family of single-stranded, negative-sense RNA viruses. HeV is classified as a Biosafety Level-4 (BSL-4) agent, as it is highly pathogenic and is often fatal ...
Mingyue Chen, Mingyue Chen, Mingyue Chen, Mary Tachedjian, Glenn A. Marsh, Jie Cui, Jie Cui, Lin-Fa Wang, Lin-Fa Wang   +8 more
doaj   +1 more source