Results 31 to 40 of about 7,241 (141)

The Cedar Project: exploring the role of colonial harms and childhood maltreatment on HIV and hepatitis C infection in a cohort study involving young Indigenous people who use drugs in two Canadian cities

BMJ Open, 2021
Objectives This study examined associations between childhood maltreatment, colonial harms and sex/drug-related risks for HIV and hepatitis C virus (HCV) infection among young Indigenous people who use drugs.Design The Cedar Project is a cohort involving
Martin T Schechter, Victoria Thomas, Margo E Pearce, Kate Jongbloed, Sherri Pooyak, Wenecwtsin M Christian, Maaxswxw Gibuu (White Wolf) Mary Teegee, Nadine R Caron, Earl Henderson, David Zamar, Eric M Yoshida, Patricia M Spittal   +11 more
doaj   +1 more source

Potential entry receptors for human γ-herpesvirus into epithelial cells: A plausible therapeutic target for viral infections

Tumour Virus Research, 2021
Herpesviruses are ubiquitous viruses, specifically the Epstein Barr virus (EBV). EBV and Kaposi's sarcoma-associated herpesvirus (KSHV) establish their latency for a long period in B-cells and their reactivation instigates dreadful diseases from cancer ...
Annu Rani, Shweta Jakhmola, Srikanth Karnati, Hamendra Singh Parmar, Hem Chandra Jha   +4 more
doaj   +1 more source

Single‐Injection Multi‐Omics Analysis by Direct Infusion Mass Spectrometry

Angewandte Chemie, Volume 138, Issue 20, 11 May 2026.
A high‐throughput direct infusion mass spectrometry platform, enabled by gas‐phase ion mobility separation, supports single‐injection analysis of peptides, polar metabolites, and lipids. Coupled with custom software, it identified ∽1,300 proteins and ∽600 metabolites in ∽4.3 minutes per sample, and demonstrated broad utility in macrophage polarization ...
Yuming Jiang, Ivan Salladay‐Perez, Amanda Momenzadeh, Jesús Muñoz‐Estrada, Uktarsh Tripathi, Anthony J. Covarrubias, Jesse G. Meyer   +6 more
wiley   +2 more sources

The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response. [PDF]

PLoS Pathogens, 2016
For efficient replication, viruses have developed mechanisms to evade innate immune responses, including the antiviral type-I interferon (IFN-I) system.
Preeti Bharaj, Yao E Wang, Brian E Dawes, Tatyana E Yun, Arnold Park, Benjamin Yen, Christopher F Basler, Alexander N Freiberg, Benhur Lee, Ricardo Rajsbaum   +9 more
doaj   +1 more source

Characterization of Nipah virus in differentiated bronchial epithelial cells cultured at the air-liquid interface and Cedar virus reverse genetics [PDF]

, 2023
The respiratory epithelium acts as both, a barrier of the respiratory tract to Nipah virus (NiV) entry and at the same time as a significant determinant of virus shedding.
Müller, Martin
core  

Discovery of Multitarget-Directed Ligands Against Influenza A Virus From Compound Yizhihao Through a Predictive System for Compound-Protein Interactions

Frontiers in Cellular and Infection Microbiology, 2020
Influenza A virus (IAV) is a threat to public health due to its high mutation rate and resistance to existing drugs. In this investigation, 15 targets selected from an influenza virus–host interaction network were successfully constructed as a ...
Lvjie Xu, Wen Jiang, Hao Jia, Lishu Zheng, Jianguo Xing, Ailin Liu, Guanhua Du   +6 more
doaj   +1 more source

Strategies for influenza vaccines [PDF]

, 2010
The high mutation rate of influenza virus results in antigenic drift, meaning that each of the three components in the trivalent influenza vaccine are updated regularly so that the vaccine antigen closely matches the predominant or emerging strain.
Hartgroves, Lorian Cedar Safir
core   +1 more source

Nonhuman Pedagogical Relations: Towards Conceptual Limits

Educational Theory, EarlyView.
Abstract This article considers the pedagogical relation as a relation to a nonhuman educator, wherein the educatee is a member of the Homo sapiens species. My aim is to clarify the extent to which a nonhuman‐human relation can be understood as pedagogical.
Silas C. Krabbe
wiley   +1 more source

Discovery and Genomic Characterization of a Novel Henipavirus, Angavokely Virus, from Fruit Bats in Madagascar [PDF]

, 2022
International audienceThe genus Henipavirus (family Paramyxoviridae) currently comprises seven viruses, four of which have demonstrated prior evidence of zoonotic capacity.
Madera, Sharline, Héraud, Jean-Michel, Andrianiaina, Angelo, Ranaivoson, Hafaliana C, Andry, Santino, DeRisi, Joseph, L., Kistler, Amy, Ranaivoson, Hafaliana, Ahyong, Vida, Tato, Cristina, M., Randriambolamanantsoa, Tsiry H, Ravelomanantsoa, Ny Anjara Fifi, DeRisi, Joseph L, Aguilar, Hector, C., Brook, Cara, E., Aguilar, Hector C, Brook, Cara E, Raharinosy, Vololoniaina, Randriambolamanantsoa, Tsiry, H., Lacoste, Vincent, Dussart, Philippe, Tato, Cristina M   +21 more
core   +1 more source

Risk of injury associated with the sedative potential of second‐generation antihistamines: A nationwide retrospective cohort study

British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2230-2238, July 2026.
Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi, Shotaro Aso, So Sato, Hideo Yasunaga   +3 more
wiley   +1 more source