Results 31 to 40 of about 26,214 (161)

The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response. [PDF]

open access: yesPLoS Pathogens, 2016
For efficient replication, viruses have developed mechanisms to evade innate immune responses, including the antiviral type-I interferon (IFN-I) system.
Preeti Bharaj   +9 more
doaj   +1 more source

Complete Genome Sequences of Paenibacillus Larvae Phages BN12, Dragolir, Kiel007, Leyra, Likha, Pagassa, PBL1c, and Tadhana [PDF]

open access: yes, 2018
We present here the complete genomes of eight phages that infect Paenibacillus larvae, the causative agent of American foulbrood in honeybees. Phage PBL1c was originally isolated in 1984 from a P.
Berg, Jordan A.   +22 more
core   +2 more sources

Discovery of Multitarget-Directed Ligands Against Influenza A Virus From Compound Yizhihao Through a Predictive System for Compound-Protein Interactions

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Influenza A virus (IAV) is a threat to public health due to its high mutation rate and resistance to existing drugs. In this investigation, 15 targets selected from an influenza virus–host interaction network were successfully constructed as a ...
Lvjie Xu   +6 more
doaj   +1 more source

Additional file 1 of The role of N-linked glycosylation in proteolytic processing and cell surface transport of the Cedar virus fusion protein

open access: yes, 2022
Additional file 1: Sequence information for codon-optimized CedV F HAtag gene. Start and stop codon are highlighted in bold and are underlined. CedV F gene was codon-optimized according to the human codon usage bias and synthesized by Gene Art. Additionally, the coding information for an HA-Tag was included.
Fischer, Kerstin   +4 more
openaire   +1 more source

The Update, February 13, 2012 [PDF]

open access: yes, 2012
The Update is a bi-weekly web newsletter published by the Iowa Department of Public Health's Bureau of Family Health. It is posted the second and fourth week of every month, and provides useful job resource information for departmental health care ...

core  

Pink Cedar (Acrocarpus fraxinifolius): its prophylactic role against APAP–induced organs toxicity in rats and its antiviral activity against Herpes simplex virus type 1 [PDF]

open access: yes, 2018
AbstractThe possible protective effects of methanolic extractAcrocarpus fraxinifoliusleaves (MEAFL) were assessed against the APAP–induced organ toxicity in male rats. Also, the content of polyphenols extracted from AFL was studied, and their relationship with antioxidant activity was investigated.
Eman A. Abdelghffar   +4 more
openaire   +1 more source

Single‐Injection Multi‐Omics Analysis by Direct Infusion Mass Spectrometry

open access: yesAngewandte Chemie International Edition, EarlyView.
A high‐throughput direct infusion mass spectrometry platform, enabled by gas‐phase ion mobility separation, supports single‐injection analysis of peptides, polar metabolites, and lipids. Coupled with custom software, it identified ∽1,300 proteins and ∽600 metabolites in ∽4.3 minutes per sample, and demonstrated broad utility in macrophage polarization ...
Yuming Jiang   +6 more
wiley   +1 more source

Iowa Animal Industry News, 2012, Vol. 14, no. 1 [PDF]

open access: yes, 2012
Newsletter produced by Department of Agriculture and Land Stewardship about the animal industry in Iowa.Previously titled Animal Industry ...

core  

Risk of injury associated with the sedative potential of second‐generation antihistamines: A nationwide retrospective cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Individual second‐generation antihistamines may possess differential sedative potential due to the variability in central histamine receptor H1 occupancy. This study aimed to evaluate whether the sedative potential of second‐generation antihistamines is associated with the risk of injury during Japan's pollen season. Methods We conducted a
Jumpei Taniguchi   +3 more
wiley   +1 more source

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo   +13 more
wiley   +1 more source

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