Results 11 to 20 of about 7,241 (141)

Rousettus aegyptiacus Fruit Bats Do Not Support Productive Replication of Cedar Virus upon Experimental Challenge [PDF]

Viruses
Cedar henipavirus (CedV), which was isolated from the urine of pteropodid bats in Australia, belongs to the genus Henipavirus in the family of Paramyxoviridae.
Björn-Patrick Mohl, Sandra Diederich, Kerstin Fischer, Anne Balkema-Buschmann   +3 more
doaj   +5 more sources

Serologic Evidence of Human Exposure to Bat-Borne Zoonotic Paramyxoviruses, Cambodia [PDF]

Viruses
Fruit bats in the genus Pteropus are the natural reservoirs for zoonotic paramyxoviruses, notably henipaviruses and pararubulaviruses, which are found across Southeast Asia and Oceania.
Neil Mittal, Spencer L. Sterling, Phireak Hip, Dolyce H. W. Low, Piseth Ly, Menghou Mao, Pidor Ouch, Adrian C. Paskey, Lianying Yan, Alan Hitch, Gavin J. D. Smith, Jeffery Hertz, Andrew G. Letizia, Ian H. Mendenhall, Eric D. Laing   +14 more
doaj   +3 more sources

Relevance of potential endocytosis motifs in Cedar virus glycoprotein G for its biological activity [PDF]

Journal of Virology
The glycoprotein (G) and fusion protein (F) of henipaviruses play crucial roles in receptor binding and entry into host cells, also enabling virus spread from cell to cell without the release of infectious particles.
Céline Burrer, Inga Hund, Carolin Rüdiger, Sven Reiche, Martin H. Groschup, Birke A. Tews, Dmitry S. Ushakov, Kerstin Fischer, Sandra Diederich   +8 more
doaj   +3 more sources

Ephrin B1 and B2 Mediate Cedar Virus Entry into Egyptian Fruit Bat Cells [PDF]

Viruses
Cedar virus (CedV), closely related to the Hendra and Nipah viruses, is a novel Henipavirus that was originally isolated from flying foxes in Australia in 2012. Although its glycoprotein G exhibits relatively low sequence similarity with its counterparts
Lea Lenhard, Martin Müller, Sandra Diederich, Lisa Loerzer, Virginia Friedrichs, Bernd Köllner, Stefan Finke, Anca Dorhoi, Gang Pei   +8 more
doaj   +4 more sources

Analysis of Recombinant Cedar Virus Infection and Cross-Protection Against Related Henipaviruses in African Green Monkeys [PDF]

Viruses
Cedar virus (CedV), related to the highly pathogenic bat-borne henipaviruses, Hendra virus (HeV) and Nipah virus (NiV), is non-pathogenic in small animal models, likely due to the inability to produce interferon-antagonist proteins.
Declan D. Pigeaud, Moushimi Amaya, Viktoriya Borisevich, Karla A. Fenton, Krystle N. Agans, Courtney Woolsey, Antony S. Dimitrov, Abhishek N. Prasad, Natalie S. Dobias, Daniel J. Deer, Joan B. Geisbert, Robert W. Cross, Christopher C. Broder, Thomas W. Geisbert   +13 more
doaj   +4 more sources

A recombinant Cedar virus based high-throughput screening assay for henipavirus antiviral discovery [PDF]

Antiviral Research, 2021
Nipah virus (NiV) and Hendra virus (HeV) are highly pathogenic, bat-borne paramyxoviruses in the genus Henipavirus that cause severe and often fatal acute respiratory and/or neurologic diseases in humans and livestock. There are currently no approved antiviral therapeutics or vaccines for use in humans to treat or prevent NiV or HeV infection.
Moushimi Amaya, Han Cheng, Viktoriya Borisevich   +2 more
exaly   +4 more sources

Tetracistronic minigenomes elucidate a functional promoter for Ghana virus and unveils Cedar virus replicase promiscuity for all henipaviruses. [PDF]

J Virol
Batborne henipaviruses, such as Nipah and Hendra viruses, represent a major threat to global health due to their propensity for spillover, severe pathogenicity, and high mortality rate in human hosts.
Haas GD, Kowdle S, Schmitz KS, Azarm KD, Johnson KN, Klain WR, Freiberg AN, Cox RM, Plemper RK, Lee B.   +9 more
europepmc   +7 more sources

Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2019
Cedar virus (CedV) is a bat-borne henipavirus related to Nipah virus (NiV) and Hendra virus (HeV), zoonotic agents of fatal human disease. CedV receptor-binding protein (G) shares only ∼30% sequence identity with those of NiV and HeV, although they can all use ephrin-B2 as an entry receptor. We demonstrate that CedV also enters cells through additional
Chanakha K Navaratnarajah, Spencer L Sterling, Glenn A Marsh   +2 more
exaly   +5 more sources

Are Respiratory Viruses Involved in Preseasonal Symptoms or Severity in Japanese Cedar Pollinosis?

Allergy & Rhinology, 2016
Background Respiratory virus infections are involved in asthma exacerbations. However, there are no reports of the relationship between respiratory virus infections and Japanese cedar pollinosis.
Hirokuni Otsuka M.D., Hiroyuki Tsukagoshi Ph.D., Hirokazu Kimura M.D., Ikuo Takanashi Ph.D., Kimihiro Okubo M.D.   +4 more
doaj   +2 more sources

Functional Analysis of the Fusion and Attachment Glycoproteins of Mojiang Henipavirus

Viruses, 2021
Mojiang virus (MojV) is the first henipavirus identified in a rodent and known only by sequence data, whereas all other henipaviruses have been isolated from bats (Hendra virus, Nipah virus, Cedar virus) or discovered by sequence data from material of ...
Sofia Cheliout Da Silva, Lianying Yan, Ha V. Dang, Kai Xu, Jonathan H. Epstein, David Veesler, Christopher C. Broder   +6 more
doaj   +2 more sources