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The impacts of biological invasions
ABSTRACT The Anthropocene is characterised by a continuous human‐mediated reshuffling of the distributions of species globally. Both intentional and unintentional introductions have resulted in numerous species being translocated beyond their native ranges, often leading to their establishment and subsequent spread – a process referred to as biological
Phillip J. Haubrock +42 more
wiley +1 more source
Additional file 1: Sequence information for codon-optimized CedV F HAtag gene. Start and stop codon are highlighted in bold and are underlined. CedV F gene was codon-optimized according to the human codon usage bias and synthesized by Gene Art. Additionally, the coding information for an HA-Tag was included.
Fischer, Kerstin +4 more
openaire +1 more source
Nipah virus and Hendra virus are highly pathogenic henipaviruses for which there are no approved therapeutics for use in humans. Using recombinant Cedar virus expressing luciferase (rCedV-Luc) as a CL2 surrogate, we screened a library of 2,703 Food and Drug Administration (FDA)-approved compounds, yielding 5 promising candidates ...
Emily Clayton +5 more
openaire +2 more sources
A Comparative Assessment of the Pathogenic Potential of Newly Discovered Henipaviruses
Recent advances in high-throughput sequencing technologies have led to the discovery of a plethora of previously unknown viruses in animal samples. Some of these newly detected viruses are closely related to human pathogens.
Kristina Meier +3 more
doaj +1 more source
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo +13 more
wiley +1 more source
Molecular Characterisation of Flavivirus Interactions with the Host Innate Immune Response [PDF]
The emergence of zoonotic viruses is an inherent risk to our global civilisation as we encroach on new environments and increase our reliance on high‐intensity farming to feed a growing population.
Coldbeck-Shackley, Rosa Cedar
core
Analysis of Nipah Virus Codon Usage and Adaptation to Hosts
A recent outbreak of Nipah virus (NiV) in India has caused 17 deaths in people living in districts of Kerala state. Its zoonotic nature, as well as high rate of human-to-human transmission, has led researchers worldwide to work toward understanding the ...
Rekha Khandia +8 more
doaj +1 more source
Biting or irritating insects are a threat to the health and welfare of grazing animals. This systematic review reveals that several shrubs and bushes growing in the alpine area have insecticidal, insect‐repellent and/or attractant properties. The alder Alnus glutinosa, juniper Juniperus communis, spruce Picea abies and walnut Juglans regia are ...
Theresa Schlittenlacher +3 more
wiley +1 more source
Molecular genetic analysis of siRNA biogenesis and function in Arabidopsis thaliana [PDF]
In diverse eukaryotes, small RNA products of Dicer-like (DCL) proteins regulate mRNA stability or translation, and direct chromatin modifications to genomic regions, phenomena collectively known as RNA silencing.
Blevins, Todd Lucas
core +1 more source
Pink Cedar ( Acrocarpus fraxinifolius ): its prophylactic role against APAP–induced organs toxicity in rats and its antiviral activity against Herpes simplex virus type 1 [PDF]
Abstract The possible protective effects of methanolic extract Acrocarpus fraxinifolius leaves (MEAFL) were assessed against the APAP–induced organ toxicity in male rats. Also, the content of polyphenols extracted from AFL was studied, and their relationship with antioxidant ...
Eman A. Abdelghffar +4 more
openaire +1 more source

