Results 1 to 10 of about 47,640 (246)

Clinical pharmacology of cefazolin

Advances in Biomedical and Health Sciences, 2022
Cefazolin is a first-generation cephalosporin that is active against gram-positive bacteria and has modest activity against gram-negative organisms, and cefazolin is excreted by glomerular filtration.
Gian Maria Pacifici
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Cefazolin versus alternative antibiotics for perioperative prophylaxis in patients labeled as cephalosporin allergic. [PDF]

Antimicrob Steward Healthc Epidemiol
Jackson J, Corsini Campioli C, Crockett R, Loomis E, Cole K, Schreier DJ, Arensman Hannan K.   +6 more
europepmc   +3 more sources

Overproduction of Chromosomal ampC β-Lactamase Gene Maintains Resistance to Cefazolin in Escherichia coli Isolates

Microbiology Spectrum, 2022
Cefazolin, an active in vitro agent against Escherichia coli, is used to treat urinary and biliary tract infections. Cefazolin is used widely as an antibiotic, and the increase in the emergence of cefazolin-resistant E.
Masato Kawamura, Ryota Ito, Yurina Tamura, Mio Takahashi, Miho Umenai, Yuriko Chiba, Takumi Sato, Shigeru Fujimura   +7 more
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Peri-Operative Dosage and Therapeutic Concentrations of Cefazolin Administered for Surgical Site Infection Prophylaxis in Elective Surgery-A Systematic Review. [PDF]

Antibiotics (Basel)
Ryan R, Bosnak C, Bright M, Cheng V, Velli G, van Zundert A, Lipman J, Roberts JA.   +7 more
europepmc   +3 more sources

Durability of the two-lumen catheter in hemodialysis patients; Ethanol 70%-heparin versus cefazolin-heparin: a randomized, double-blind clinical trial study [PDF]

Journal of Nephropharmacology, 2023
Introduction: Maintenance of hemodialysis catheters is essential for the patients and medical staff due to their repeated use for hemodialysis and other therapeutic interventions in the hospital.
Hadi Yousefi, Mehdi Hosseinifard, Mojgan Falaki, Fariba Asadi Noghabi, Hamidreza Samimagham, Mohsen Yousefi, Hossein Mardanparvar, Jahanbakhsh Vahdatnejad   +7 more
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Population pharmacokinetic model of cefazolin in total hip arthroplasty

Scientific Reports, 2021
Cefazolin is an antibiotic recommended for infection prevention in total hip arthroplasty (THA). However, the dosing regimen necessary to achieve therapeutic concentrations in obese patients remains unclear.
J. Lanoiselée, R. Chaux, S. Hodin, S. Bourayou, A. Gibert, R. Philippot, S. Molliex, P. J. Zufferey, X. Delavenne, E. Ollier   +9 more
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Safety of Cefazolin in Prophylaxis in Β-Lactam Allergic Children

Bezmiâlem Science, 2022
Objective:Cefazolin is a first-generation cephalosporin, particularly effective against gram positive agents such as staphylococci and streptococci. Despite this narrow spectrum, it is important in surgical prophylaxis.
Ayşe SÜLEYMAN, Esra YÜCEL, Zeynep TAMAY, Nermin GÜLER   +3 more
doaj   +1 more source

P-1123. Optimizing use of Cefazolin for Surgical Prophylaxis in Patients with Penicillin Allergy Labels [PDF]

Open Forum Infect Dis
Amanda Binkley, Olajumoke Fadugba, Patrick Kim, Laurel Adams, M Kit Delgado, Jeffrey Ebert, Athena Lee, Aria Xiong, Nikhil K. Mull, Kristel Frey, Arielle Berk, Jesal Shah, Naasha J Talati   +12 more
europepmc   +3 more sources

Application of a Physiologically Based Pharmacokinetic Model to Predict Cefazolin and Cefuroxime Disposition in Obese Pregnant Women Undergoing Caesarean Section

Pharmaceutics, 2022
Intravenous (IV) cefuroxime and cefazolin are used prophylactically in caesarean sections (CS). Currently, there are concerns regarding sub-optimal dosing in obese pregnant women compared to lean pregnant women prior to CS.
Hanadi H. Alrammaal, Khaled Abduljalil, Victoria Hodgetts Morton, R. Katie Morris, John F. Marriott, Hsu P. Chong, Hannah K. Batchelor   +6 more
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Antimicrobial activity of impregnated antibiotic matrix materials for bone tissue defect reconstruction [PDF]

Archives of the Balkan Medical Union, 2020
Introduction. Combinations of fibrous materials with therapeutic agents as a drug delivery system are currently studied. A new direction has appeared in reconstructive surgery – tissue engineering, which aims to restore biological functions, i.e.
Andrii V. PANTUS, Mykola M. ROZHKO, Roman V. KUTSYK, Ruslan V. KOZOVYI, Mykola V. MELNICHUK   +4 more
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