Deranged Coagulation Profile Secondary to Cefazolin Use: Case Report [PDF]
Cefazolin is a widely used first-generation cephalosporin. While generally well tolerated, several case reports have described severe coagulopathy induced by intravenous (IV) cefazolin. This was seen particularly in patients with impaired renal function,
Jinghao Nicholas Ngiam +7 more
doaj +2 more sources
Background: Periprosthetic joint infection (PJI) remains one of the most devastating complications following total joint arthroplasty. Appropriate prophylactic antimicrobial administration and antibiotic stewardship are major factors impacting the risk ...
Dionisio Ortiz, III, MD +4 more
doaj +2 more sources
Cefazolin Concentration in the Mediastinal Adipose Tissue of Patients Undergoing Cardiac Surgery
Objective: To measure the concentration of cefazolin in the anterior mediastinal adipose tissue of patients undergoing cardiac surgery, determining the variation of cefazolin concentration. Methods: Two samples of approximately 1g of subcutaneous tissue
Rodrigo Mezzalira Tchaick +5 more
doaj +2 more sources
Cefazolin-induced coagulopathy: a case report [PDF]
Objective We report a case of cefazolin-induced coagulopathy, highlighting the importance of maintaining a high index of suspicion for this rare adverse effect of cefazolin.
Olivier Zerbib +4 more
doaj +2 more sources
Cerebrospinal Pharmacokinetic Modeling and Pharmacodynamic Simulation of High-Dose Cefazolin for Meningitis Caused by Methicillin-Susceptible Staphylococcus aureus [PDF]
Background: Cefazolin is being increasingly used to treat central nervous system infections caused by methicillin-susceptible Staphylococcus aureus (MSSA) to mitigate the side effects of existing anti-Staphylococcal drugs.
Tetsushu Onita +4 more
doaj +2 more sources
Antibiotic Use in Surgical Wards: A Point Prevalence Survey Based on the WHO AWaRe Methodology [PDF]
Background/Objectives: In surgical antibiotic prophylaxis (SAP), most studies continue to report the number of prescriptions aggregated at the hospital level, rarely integrating the World Health Organization (WHO) Access, Watch, and Reserve (AWaRe ...
Jacopo Dolcini +14 more
doaj +2 more sources
Intraoperative Redosing of Cefazolin and Risk for Surgical Site Infection in Cardiac Surgery [PDF]
Intraoperative redosing of prophylactic antibiotics is recommended for prolonged surgical procedures, although its efficacy has not been assessed. We retrospectively compared the risk of surgical site infections in 1,548 patients who underwent cardiac ...
Giardina, Richard +2 more
core +4 more sources
The Cefazolin Inoculum Effect: An Underappreciated Factor in MSSA Treatment Strategies. [PDF]
Srivastava P +7 more
europepmc +3 more sources
Cefazolin inoculum effect among methicillinsusceptible Staphylococcus aureus isolated from patients with skin infections [PDF]
Objective. To evaluate frequency and intensity of cefazolin inoculum effect among methicillin-susceptible staphylococci isolated from patients with skin infections. Materials and Methods.
Vaganova А.N. +7 more
doaj +1 more source
Removal of the Cefazolin Antibiotic Using Polyaniline Resin-Polyethylene Glycol from Aqueous Medium [PDF]
Cefazolin is a widely used antibiotic in the treatment of bacterial infections that enters the water sources in original or metabolized form through the discharge of sewage and effluents.
Mozhgan Arman +3 more
doaj +1 more source

