Results 41 to 50 of about 44,476 (276)

Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]

, 2016
Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba, Inayathullah, Mohammed, Kim, K. M., Parekh, Mansi B., Pothineni, Venkata Raveendra, Rajadas, Jayakumar, Samineni, A. V., Solow-Cordero, David, Tayebi, Lobat, Wagh, Dhananjay   +9 more
core   +3 more sources

Deranged Coagulation Profile Secondary to Cefazolin Use: Case Report

Infectious Disease Reports, 2021
Cefazolin is a widely used first-generation cephalosporin. While generally well tolerated, several case reports have described severe coagulopathy induced by intravenous (IV) cefazolin. This was seen particularly in patients with impaired renal function,
Jinghao Nicholas Ngiam, Tze Sian Liong, Sai Meng Tham, Thanawin Pramotedham, Rawan AlAgha, Joy Yong, Paul Anantharajah Tambyah, Lionel Hon Wai Lum   +7 more
doaj   +1 more source

Cefazolin as a cause of leukocytoclastic vasculitis

Clinical Case Reports, 2017
Key Clinical MessageLeukocytoclastic vasculitis (LCV) is a cutaneous small vessel vasculitis characterized by cutaneous manifestations in the form of palpable purpura, and rarely bullae, vesicles, and ulcerations. Although rare, cephalosporins such as cefazolin, should be recognized to have a potential to trigger LCV.
Naveed Ali, Nidhi Karia, Richard Goldhahn   +2 more
openaire   +3 more sources

Cefazolin Prophylaxis for Total Joint Arthroplasty: Obese Patients Are Frequently Underdosed and at Increased Risk of Periprosthetic Joint Infection [PDF]

, 2018
Background One of the most effective prophylactic strategies against periprosthetic joint infection (PJI) is administration of perioperative antibiotics. Many orthopedic surgeons are unaware of the weight-based dosing protocol for cefazolin.
Greenky, Max R., Kheir, Michael M., Parvisi, Javad, Rondon, Alexander J., Shohat, Noam, Tan, Timothy L.   +5 more
core   +1 more source

Impact of Cefazolin Shortage on Clinical Outcomes of Adult Patients with Bacteremia Caused by Methicillin-Susceptible Staphylococcus aureus in a Tertiary Care University Hospital

Antibiotics, 2021
Cefazolin is an essential antibiotic used for treating bacteremia; in particular, it is recommended as a first-line agent for infections caused by methicillin-susceptible Staphylococcusaureus (MSSA).
Atsushi Uda, Kenichiro Onuma, Katsumi Shigemura, Koichi Kitagawa, Yonmin Yan, Kayo Osawa, Ikuko Yano, Takayuki Miyara   +7 more
doaj   +1 more source

A Comparative Evaluation of Risk Factors and Various Antibiotic Regimens in Postoperative Neurosurgical Infections: A Prospective Randomized Controlled Study

Indian Journal of Neurosurgery, 2017
Introduction Postoperative neurosurgical infections are a major problem, and the importance of keeping them to an absolute minimum cannot but be overemphasized.
R. Shetty, S. Dwarakanath, H.B. Veena Kumari, S. Sampath, B.A. Chandramouli   +4 more
doaj   +1 more source

Bicarbonate Resensitization of Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics. [PDF]

, 2019
Endovascular infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a major health care concern, especially infective endocarditis (IE).
Abdelhady, Wessam, Bayer, Arnold S, Chambers, Henry F, Ersoy, Selvi C, Li, Liang, Xiong, Yan Q   +5 more
core  

3D Bioprinting‐Assisted Engineering of Stem Cell‐Laden Hybrid Biopatches With Distinct Geometric Patterns Considering the Mechanical Characteristics of Regular and Irregular Connective Tissues

Advanced Healthcare Materials, EarlyView.
A hybrid biopatch platform integrating 3D printed polymeric patterns with stem cell‐laden collagen bioinks is developed to mimic the mechanical properties of connective tissues. By tailoring geometric architectures, the constructs replicate anisotropic or isotropic mechanics, enhancing tissue‐specific regeneration.
Minjun Ahn, Gyu Tae Park, Arvind Kumar Shukla, Boguen Kwon, Jae Ho Kim, Eui‐Suk Sung, Byoung Soo Kim   +6 more
wiley   +1 more source

Penicillin Allergy Assessment and Skin Testing in the Outpatient Setting [PDF]

, 2019
Penicillin allergies are among of the most commonly reported allergies, yet only 10% of these patients are truly allergic. This leads to potential inadvertent negative consequences for patients and makes treatment decisions challenging for clinicians ...
Avery, Lisa M., Bookstaver, P. Brandon, Justo, Julie Ann, Kufel, Wesley D.   +3 more
core   +3 more sources

Prolonged Prophylactic Antibiotics Based on Preoperative Bile Culture Reduce Surgical Site Infections After Pancreaticoduodenectomy Following Preoperative Biliary Drainage: A Propensity‐Matched Analysis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Objective The optimum duration of prophylactic antibiotics after pancreaticoduodenectomy following preoperative biliary drainage to prevent surgical site infections remains controversial. We evaluate whether a prolonged course of prophylactic antibiotics reduces surgical site infection after pancreaticoduodenectomy following biliary drainage ...
Kyohei Matsumoto, Atsushi Shimizu, Yuji Kitahata, Akihiro Takeuchi, Hideki Motobayashi, Masatoshi Sato, Tomohiro Yoshimura, Shinya Hayami, Atsushi Miyamoto, Manabu Kawai   +9 more
wiley   +1 more source