Results 31 to 40 of about 1,567 (130)

Recent Advances in Pyridine Scaffold: Focus on Chemistry, Synthesis, and Antibacterial Activities

open access: yesBioMed Research International, Volume 2023, Issue 1, 2023., 2023
Multidrug‐resistant (MDR) pathogens have created a fatal problem for human health and antimicrobial treatment. Among the currently available antibiotics, many are inactive against MDR pathogens. In this context, heterocyclic compounds/drugs play a vital role. Thus, it is very much essential to explore new research to combat the issue.
Md. Badrul Islam   +7 more
wiley   +1 more source

Current state of antimicrobial stewardship and organ transplantation in Spain

open access: yesTransplant Infectious Disease, Volume 24, Issue 5, October 2022., 2022
Abstract Introduction Solid‐organ transplantation (SOT) remains the best therapeutic option for end‐stage organ disease. Regrettably, SOT recipients are disproportionately affected by nosocomial infections produced by multidrug‐resistant (MDR) microorganisms and antimicrobial adverse events.
Jose Tiago Silva, José María Aguado
wiley   +1 more source

The clinical outcomes of COVID‐19 in HIV‐positive patients: A systematic review of current evidence

open access: yesImmunity, Inflammation and Disease, Volume 9, Issue 4, Page 1160-1185, December 2021., 2021
Abstract Introduction Patients with chronic underlying diseases are more susceptible to coronavirus disease 2019 (COVID‐19) complications. Recent studies showed people living with HIV (PLWH) are not at greater risk than the general population. Few studies have reviewed the impacts of COVID‐19 on PLWH.
SeyedAhmad SeyedAlinaghi   +12 more
wiley   +1 more source

Regulatory utility of pharmacometrics in the development and evaluation of antimicrobial agents and its recent progress in China

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 10, Issue 12, Page 1466-1478, December 2021., 2021
Abstract Pharmacometrics is an emerging science that interprets drug, disease, and trial information in a mathematical fashion to inform and facilitate efficient drug development and/or regulatory decisions. Pharmacometrics study is increasingly adopted in the regulatory review of new antimicrobial agents.
Ming Zhao   +9 more
wiley   +1 more source

Ceftaroline fosamil: development a rapid HPLC method indicating stability and bioassay for determination in pharmaceutical formulation, stability and cytotoxicity studies

open access: yesDrug Analytical Research, 2021
The present study reports the development and validation of a microbiological assay. To assess this methodology, the method was developed and validated for the quantification of CEF by high performance liquid chromatography (HPLC).
Idamir José Mascarello Junior   +4 more
doaj   +4 more sources

Comparing Several Treatments with Antibiotics for Community-Acquired Pneumonia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

open access: yesIranian Journal of Public Health, 2021
Background: We aimed to review relevant randomized controlled trials to assess the relative clinical effects of antibiotic treatment of patients with community-acquired pneumonia (CAP).
Fusheng Bai, Xinming Li
doaj   +1 more source

Clinically Approved Antibiotics from 2010 to 2022

open access: yesCHIMIA, 2023
This review discusses small molecule antibiotics approved for clinical use in the time frame 2010-2022. This time span saw the approval of four synthetic antibiotics (bedaquiline, pretomanid, delafloxacin, tedizolid), nine natural product derivatives ...
Erik Jung, Karl Gademann
doaj   +1 more source

Evaluating the antibacterial activity of ceftaroline against clinical isolates of methicillin-susceptible and- resistant Staphylococcus aureus in Kuwait hospitals

open access: yesJournal of Infection and Public Health, 2020
Ceftaroline fosamil has been approved by the US Food and Drug Administration for the treatment of skin and soft tissue infections, including those caused by methicillin-resistant Staphylococcus aureus and community-acquired bacterial pneumonia.
Wadha Alfouzan   +3 more
doaj   +1 more source

Ceftaroline-related acute eosinophilic pneumonia

open access: yesLung India, 2021
Ceftaroline fosamil is a novel 5th generation broad-spectrum oxyimino-cephalosporin with activity against Staphylococcus aureus, including methicillin-resistant S.
Zaw Min   +4 more
doaj   +1 more source

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