Results 31 to 40 of about 1,567 (130)
Recent Advances in Pyridine Scaffold: Focus on Chemistry, Synthesis, and Antibacterial Activities
Multidrug‐resistant (MDR) pathogens have created a fatal problem for human health and antimicrobial treatment. Among the currently available antibiotics, many are inactive against MDR pathogens. In this context, heterocyclic compounds/drugs play a vital role. Thus, it is very much essential to explore new research to combat the issue.
Md. Badrul Islam +7 more
wiley +1 more source
Current state of antimicrobial stewardship and organ transplantation in Spain
Abstract Introduction Solid‐organ transplantation (SOT) remains the best therapeutic option for end‐stage organ disease. Regrettably, SOT recipients are disproportionately affected by nosocomial infections produced by multidrug‐resistant (MDR) microorganisms and antimicrobial adverse events.
Jose Tiago Silva, José María Aguado
wiley +1 more source
The clinical outcomes of COVID‐19 in HIV‐positive patients: A systematic review of current evidence
Abstract Introduction Patients with chronic underlying diseases are more susceptible to coronavirus disease 2019 (COVID‐19) complications. Recent studies showed people living with HIV (PLWH) are not at greater risk than the general population. Few studies have reviewed the impacts of COVID‐19 on PLWH.
SeyedAhmad SeyedAlinaghi +12 more
wiley +1 more source
Abstract Pharmacometrics is an emerging science that interprets drug, disease, and trial information in a mathematical fashion to inform and facilitate efficient drug development and/or regulatory decisions. Pharmacometrics study is increasingly adopted in the regulatory review of new antimicrobial agents.
Ming Zhao +9 more
wiley +1 more source
The present study reports the development and validation of a microbiological assay. To assess this methodology, the method was developed and validated for the quantification of CEF by high performance liquid chromatography (HPLC).
Idamir José Mascarello Junior +4 more
doaj +4 more sources
Background: We aimed to review relevant randomized controlled trials to assess the relative clinical effects of antibiotic treatment of patients with community-acquired pneumonia (CAP).
Fusheng Bai, Xinming Li
doaj +1 more source
Clinically Approved Antibiotics from 2010 to 2022
This review discusses small molecule antibiotics approved for clinical use in the time frame 2010-2022. This time span saw the approval of four synthetic antibiotics (bedaquiline, pretomanid, delafloxacin, tedizolid), nine natural product derivatives ...
Erik Jung, Karl Gademann
doaj +1 more source
Ceftaroline fosamil has been approved by the US Food and Drug Administration for the treatment of skin and soft tissue infections, including those caused by methicillin-resistant Staphylococcus aureus and community-acquired bacterial pneumonia.
Wadha Alfouzan +3 more
doaj +1 more source
Safety, local tolerability and pharmacokinetics of ceftaroline fosamil administered in a reduced infusion volume [PDF]
Helen Broadhurst, Timi Edeki
exaly +2 more sources
Ceftaroline-related acute eosinophilic pneumonia
Ceftaroline fosamil is a novel 5th generation broad-spectrum oxyimino-cephalosporin with activity against Staphylococcus aureus, including methicillin-resistant S.
Zaw Min +4 more
doaj +1 more source

