Ceftaroline fosamil laden allograft: A new modality in reducing infection?
Purpose: Allograft infection remains the greatest challenge in orthopaedic reconstructive surgery especially methicillin-resistant Staphylococcus aureus (MRSA). This risk can be minimized with the use of antibiotic laden allograft (ALA) via iontophoresis.
Vivek Ajit Singh +3 more
doaj +3 more sources
Efficacy and safety of ceftaroline: systematic review and meta-analysis
Background: Resistance to antibiotics is steadily increasing. Ceftaroline has a broad spectrum of activity against clinically relevant gram-positive strains including methicillin-resistant Staphylococcus aureus .
Maria T. Rosanova +3 more
doaj +2 more sources
Intra-Lot and Inter-Lot Variability in Ceftaroline Fosamil. [PDF]
Intra-lot and inter-lot variability in ceftaroline fosamil was detected using Fourier transform near-infrared spectrometry. One vial of 18 sampled from Lot0013E06 appeared 9.0 SDs from the center of the rest of the vials.
Almeter PJ +4 more
europepmc +2 more sources
Ceftaroline Fosamil for Treatment of Pediatric Complicated Skin and Soft Tissue Infections and Community-Acquired Pneumonia. [PDF]
Community-acquired pneumonia (CAP)/community-acquired bacterial pneumonia (CABP) and complicated skin and soft tissue infection (cSSTI)/acute bacterial skin and skin structure infection (ABSSSI) represent major causes of morbidity and mortality in ...
Esposito S +4 more
europepmc +2 more sources
Ceftaroline resistance in Staphylococcus pseudintermedius gene mecA carriers
: Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) being a constant concern, ceftaroline fosamil has been recently approved as a new cephalosporin, active against MRSA, for use in humans; only rare cases of resistance have been ...
Carolina B. Scherer +4 more
doaj +2 more sources
Diego J Maselli1, Juan F Fernandez1, Christine Y Whong2, Kelly Echevarria1,3, Anoop M Nambiar1,3, Antonio Anzueto1,3, Marcos I Restrepo1,3,41University of Texas Health Science Center, San Antonio, Texas, 2Memorial Hermann – Texas Medical Center,
Maselli DJ +6 more
doaj +1 more source
Ceftaroline fosamil doses and breakpoints for Staphylococcus aureus in complicated skin and soft tissue infections. [PDF]
Objectives To describe the pharmacokinetic/pharmacodynamic (PK/PD) modelling and microbiological data that were used to support the recent European approval of ceftaroline fosamil 600 mg q8h by 2 h intravenous (iv) infusion for patients with complicated ...
Das S +6 more
europepmc +2 more sources
Ceftaroline fosamil treatment patterns and outcomes in adults with community-acquired pneumonia: a real-world multinational, retrospective study. [PDF]
Background: This multicentre, observational, retrospective chart review study assessed ceftaroline fosamil treatment patterns and outcomes in adults hospitalized with community-acquired pneumonia (CAP) in usual care settings.
Soriano A +9 more
europepmc +2 more sources
Ceftaroline In-vitro Activity against Methicillin Resistant Staphylococcal Isolates in a Rural Tertiary Health Care Centre [PDF]
Introduction: The emergence of Methicillin Resistant (MR) staphylococcal infections had led to fewer therapeutic options. Ceftaroline fosamil is the only cephalosporin approved by United States of America (USA) Food and Drug Administration (FDA) till
VIJAYA SHIVANNA +2 more
doaj +1 more source
The Dutch list of essential drugs for undergraduate medical education: A modified Delphi study
Aims Prescribing errors among junior doctors are common in clinical practice because many lack prescribing competence after graduation. This is in part due to inadequate education in clinical pharmacology and therapeutics (CP&T) in the undergraduate medical curriculum.
Erik M. Donker +52 more
wiley +1 more source

