Results 61 to 70 of about 11,837 (160)

Genomic epidemiology and ceftazidime-avibactam high-level resistance mechanisms of Pseudomonas aeruginosa in China from 2010 to 2022

Emerging Microbes and Infections
Ceftazidime-avibactam (CZA) resistance is a huge threat in the clinic; however, the underlying mechanism responsible for high-level CZA resistance in Pseudomonas aeruginosa (PA) isolates remains unknown. In this study, a total of 5,763 P.
Xi Li, Longjie Zhou, Tailong Lei, Xiaofan Zhang, Jiayao Yao, Jintao He, Haiyang Liu, Heng Cai, J. Ji, Yiwei Zhu, Yuexing Tu, Yunsong Yu, Hualing Zhou   +12 more
semanticscholar   +1 more source

Distribution and Drug‐Resistance Analysis of Uropathogens in Urinary Tract Infections

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2026, Issue 1, 2026.
Background Urinary tract infections (UTIs) are a major global health concern with increasing antimicrobial resistance. Regional data on pathogen distribution and resistance patterns are essential for guiding empirical therapy. This study aimed to investigate the distribution and antimicrobial resistance profiles of UTI pathogens in Shanghai, China, and
Weiyi Wu, Qiong Wu, Wenying Zhong, Lizhong Han, Mohsin Khurshid   +4 more
wiley   +1 more source

Pancreatic Encephalopathy: A Rare but Critical Complication of Acute Pancreatitis—A Case Report and Literature Review

Case Reports in Critical Care, Volume 2026, Issue 1, 2026.
Pancreatic encephalopathy (PE) is a rare but severe neurological complication of acute pancreatitis, characterized by cerebral edema and disruption of the blood–brain barrier due to systemic inflammation and the release of pancreatic enzymes. The pathophysiology involves a complex interplay of inflammatory cytokines and oxidative stress, leading to ...
Edith Joie Jewel M. Paras, James Ibn Aristotle B. Lingad, Jose Emmanuel M. Palo, Lipi Buch   +3 more
wiley   +1 more source

In vitro mimicry of in vivo KPC mutations by ceftazidime-avibactam: phenotypes, mechanisms, genetic structure and kinetics of enzymatic hydrolysis

Emerging Microbes and Infections
Ceftazidime-avibactam (CZA) is employed for the treatment of infections caused by Klebsiella pneumoniae carbapenemase-producing K. pneumoniae (KPC-KP). Resistance to CZA is frequently linked to point mutations in the blaKPC.
S. Shen, Chengkang Tang, Weiwei Yang, Li Ding, Renru Han, Qingyu Shi, Yan Guo, D. Yin, F. Hu   +8 more
semanticscholar   +1 more source

A Rare Case of Prosthetic Joint Infection Caused by Group D Salmonella

Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
Prosthetic joint infections (PJIs) are gaining growing attention as a healthcare issue. Salmonella spp. is a rare cause of PJI, mostly involving hip arthroplasty rather than knee arthroplasty. Therefore, clinical experience on the management of PJI involving knee arthroplasties caused by Salmonella spp. is scant.
Anna Barbiero, Lucia Graziani, Matteo Piccica, Francesco Raspanti, Luigi Zanna, Marco Mugnaini, Letizia Attala, Massimo Antonio Di Pietro, Rajib Chowdhury   +8 more
wiley   +1 more source

Antibiotic Susceptibility of Aerobic and Facultative Anaerobic Gram-Negative Rods in Hong Kong and Implications on Usefulness of Ceftazidime-Avibactam and Ceftolozane-Tazobactam

Antibiotics
Due to the increasing resistance of aerobic and facultative anaerobic Gram-negative rods, ceftazidime-avibactam and ceftolozane-tazobactam have been launched in the market in the last few years.
Jade L. L. Teng, Elaine Chan, Tsz Tuen Li, Tsz Ying Kwan, Ka Fai Chan, Wing Ho Li, Viki W. K. Tang, Man Lung Yeung, Susanna K. P. Lau, Patrick C. Y. Woo   +9 more
doaj   +1 more source

Pharmacoeconomic analysis of ceftazidime+avibactam (Zavicefta®) in the treatment of sepsis caused by carbapenem-resistant enterobacteria

Фармакоэкономика, 2019
Aim: to assess the economic outcomes of using ceftazidime + avibactam (compared with the recommended treatments) in adult patients with sepsis caused by carbapenem-resistant enterobacteria.Methods.
S. V. Nedogoda, A. S. Salasyuk, I. N. Barykina, V. O. Smirnova   +3 more
doaj   +1 more source

Myelodysplastic Syndrome With Complex Chromosomal Karyotype Abnormalities Complicated by Multiple Intestinal Perforations: A Case Report and Literature Review

Case Reports in Gastrointestinal Medicine, Volume 2026, Issue 1, 2026.
Background Myelodysplastic syndromes (MDSs) are clonal hematopoietic disorders often associated with cytogenetic abnormalities, among which trisomy 8 is one of the most common abnormalities. Trisomy 8 is linked to autoimmune manifestations, including Behçet‐like disease, especially with gastrointestinal involvement.
Zhan-Yue Niu, Ming-Fei Zhu, Ming Tao, Cheng Zhang, Fang Gu, Jun Li, MARCEL CC MACHADO   +6 more
wiley   +1 more source

Resistance to ceftazidime–avibactam and other new β-lactams in Pseudomonas aeruginosa clinical isolates: a multi-center surveillance study

Microbiology spectrum
New β-lactam–β-lactamase inhibitor combinations represent last-resort antibiotics to treat infections caused by multidrug-resistant Pseudomonas aeruginosa.
Felice Valzano, G. La Bella, T. Lopizzo, Anna Curci, L. Lupo, Elisabetta Morelli, A. Mosca, Marianna Marangi, Raffaela Melfitano, Tiziana Rollo, Rosella De Nittis, Fabio Arena   +11 more
semanticscholar   +1 more source

Cucumber Production System as a Reservoir for Clinically Important Extended‐Spectrum Beta‐Lactamase‐ and AmpC Beta‐Lactamase‐Producing Escherichia coli and Klebsiella pneumoniae Strains

International Journal of Food Science, Volume 2026, Issue 1, 2026.
This study evaluated clinically significant extended‐spectrum β‐lactamase (ESBL)‐ and AmpC β‐lactamase (AmpC)‐ producing Escherichia coli and Klebsiella pneumoniae in a cucumber production system, focusing on their potential sources and public health implications.
Manana Dlangalala, Stacey Duvenage, Erika Margarete Du Plessis, Lise Korsten, Muhammad Asif Zahoor   +4 more
wiley   +1 more source