Results 111 to 120 of about 13,550 (188)

Verification of Ceftazidime-Avibactam and Ceftolozane-Tazobactam Susceptibility Testing Methods against Carbapenem-Resistant Enterobacteriaceae and Pseudomonas aeruginosa

, 2018
Ceftazidime-avibactam and ceftolozane-tazobactam are newly approved agents for the treatment of infections caused by multidrug-resistant Gram-negative bacteria. Resistance to both agents has been described clinically.
Binghua Hao, M. Hong Nguyen, Liang Chen, A. William Pasculle, Ghady Haidar, Ellen G. Press, Ryan K. Shields, Barry N. Kreiswirth, Cornelius J. Clancy   +8 more
core   +1 more source

Investigating Gram-negative bacilli isolates’ sensitivity to ceftazidime/avibactam

Background: Multidrug resistant (MDR) Gram negative organisms are becoming increasingly common. Carbapenem resistant Enterobacterales (CRE) pose a major threat and necessitate the development of new antibiotics.
Mithilesh Kumar Jha, Mukesh Kumar, Sunali, Maneesh Kumar, Nishant Ranjan   +4 more
core   +1 more source

Tackling carbapenem resistance: ceftazidime - avibactam in contemporary clinical scenarios

International Journal of Advances in Medicine
Antimicrobial resistance poses a formidable challenge in treating severe infections, with the prevalence of extended-spectrum beta-lactamase (ESBL) - producing, Klebsiella pneumoniae carbapenemase (KPC) - producing, and multidrug-resistant (MDR) organisms on the rise.
Manish Maladkar, Shrikant Patil, Namita Anchan   +2 more
openaire   +1 more source

Impact of renal-adjusted ceftazidime/avibactam in patients with KPC-producing Klebsiella pneumoniae bloodstream infection. A retrospective cohort study

Background. Bloodstream infections (BSIs) caused by KPC-producing K. pneumoniae (KPC-Kp) are still associated with high mortality, and the game-changing drug ceftazidime/avibactam has shown suboptimal pharmacokinetics in some clinical settings ...
Federica Sacco, Antonietta Gigante, Agnese Viscido, Silvia Trapani, Michela Di Nillo, Lorenzo Volpicelli, Claudio Mastroianni, Alessandra Oliva   +7 more
core   +1 more source

Multidrug-resistant Pseudomonas aeruginosa from sputum of patients with cystic fibrosis demonstrates a high rate of susceptibility to ceftazidime–avibactam

Infection and Drug Resistance, 2018
Stan D Atkin,1 Shadaan Abid,1 Michael Foster,1 Moumita Bose,1 Ashley Keller,1 Rita Hollaway,2 Helio S Sader,3 David E Greenberg,1,4 James D Finklea,1 Mariana Castanheira,3 Raksha Jain1,4 1Department of Internal Medicine, University of Texas Southwestern ...
Atkin SD, Abid S, Foster M, Bose M, Keller A, Hollaway R, Sader HS, Greenberg DE, Finklea JD, Castanheira M, Jain R   +10 more
doaj  

Cefepime-taniborbactam and ceftibuten-ledaborbactam maintain activity against KPC variants that lead to ceftazidime-avibactam resistance. [PDF]

Antimicrob Agents Chemother
Myers CL, Stevenson A, Miller B, Daigle DM, Uehara T, Pevear DC.   +5 more
europepmc   +2 more sources

Ceftazidime-avibactam resistance evolution in <i>Pseudomonas aeruginosa</i> and implications for cross-resistance to other novel β-lactams. [PDF]

Antimicrob Agents Chemother
Dorazio AJ, Kline EG, Squires KM, Shah S, Van Tyne D, Wu JY, Pogue JM, Shields RK.   +7 more
europepmc   +1 more source

High-level ceftazidime/avibactam resistance in Escherichia coli conferred by the novel plasmid-mediated β-lactamase CMY-185 variant. [PDF]

J Antimicrob Chemother, 2023
Shropshire WC, Endres BT, Borjan J, Aitken SL, Bachman WC, McElheny CL, Wu CT, Egge SL, Khan A, Miller WR, Bhatti MM, Saharasbhojane P, Kawai A, Shields RK, Shelburne SA, Doi Y.   +15 more
europepmc   +1 more source

Risk factors for <i>in vivo</i> emergence of ceftazidime-avibactam resistance in KPC-producing <i>Klebsiella pneumoniae</i> and the associated resistance mechanisms: a case-control study. [PDF]

Microbiol Spectr
Chuang C, Liu S-Y, Ho Y-C, Chou S-H, Huang Y-R, Chin W, Ho H-L, Chen L, Lin Y-T.   +8 more
europepmc   +1 more source

Emergence of KPC-134, a KPC-2 variant associated with ceftazidime-avibactam resistance in a ST11 <i>Klebsiella pneumoniae</i> clinical strain. [PDF]

Microbiol Spectr, 2023
Huang X, Shen S, Chang F, Liu X, Yue J, Xie N, Yin L, Hu F, Xiao D.   +8 more
europepmc   +1 more source