Results 91 to 100 of about 13,550 (188)

Clinical distribution of carbapenem genotypes and resistance to ceftazidime-avibactam in Enterobacteriaceae bacteria

Frontiers in Cellular and Infection Microbiology
IntroductionBacterial resistance is a major threat to public health worldwide. To gain an understanding of the clinical infection distribution, drug resistance information, and genotype of CRE in Dongguan, China, as well as the resistance of relevant genotypes to CAZ-AVI, this research aims to improve drug resistance monitoring information in Dongguan ...
Xueyun Zhu, Xueyun Zhu, Caixia Guo, Shengxi Xu, Fei Lv, Zhusheng Guo, Sisi Lin, CongZhu Yang, Zhuliang Deng, Shaofeng Chen, Ya Huang, Zuguo Zhao, Lu Li   +12 more
openaire   +3 more sources

Effectiveness of Ceftazidime/Avibactam treatment for infections caused by Klebsiella pneumoniae Carbapenemase (KPC), a 30-day mortality perspective. Comparison of results with control groups treated with other antibiotics

Journal of Education, Health and Sport
Introduction: Infections caused by Klebsiella pneumoniae carbapenemase (KPC) pose a significant clinical challenge due to increasing antibiotic resistance.
Patrycja Paschke, Igor Miczek, Maria Sambura, Sara Rosołowska-Żak, Julia Pałuchowska, Anna Szymkowicz   +5 more
doaj   +1 more source

Ceftazidime/Avibactam: Who Says You Can’t Teach an Old Drug New Tricks?

Journal of Pharmacy & Pharmaceutical Sciences, 2016
Purpose: Gram-negative resistance continues to rise with treatment options becoming more limited. Ceftazidime/avibactam was recently approved in the United States and Europe, which combines an established third-generation cephalosporin with a new, unique,
Katie E. Barber, Jessica K. Ortwine, Ronda L Akins   +2 more
doaj   +1 more source

Pharmacodynamics of ceftazidime/avibactam against extracellular and intracellular forms of Pseudomonas aeruginosa

, 2017
Objectives: When tested in broth, avibactam reverses ceftazidime resistance in many Pseudomonas aeruginosa that express ESBLs. We examined whether similar reversal is observed against intracellular forms of P. aeruginosa.
Krause, K.M., Nichols, W. W., Muccioli, Giulio, Buyck, Julien, Van Bambeke, Françoise, Luyckx, C., Tulkens, Paul M.   +6 more
core   +1 more source

KPC variants conferring resistance to ceftazidime-avibactam in Pseudomonas aeruginosa strains

Microbiological Research
This study aimed to characterize three KPC variants (KPC-33, KPC-100, and KPC-201) obtained from a clinical isolate of Pseudomonas aeruginosa (#700), along with two induced strains C109 and C108.Genomic DNAs of #700 (ST235), C109 (ST463), and C108 (ST1076) were sequenced using Illumina and Oxford Nanopore technologies. The transferability and stability
Yanyan, Hu, Weiyi, Shen, Di, Lin, Yuchen, Wu, Yanyan, Zhang, Hongwei, Zhou, Rong, Zhang   +6 more
openaire   +2 more sources

Additional file 3 of Acetylcysteine increases sensitivity of ceftazidime-avibactam–resistant enterobacterales with different enzymatic resistance to ceftazidime-avibactam in vitro and in vivo

Additional file 3: Table S1. The MIC values against the 8 clinical isolates used in this study.
Huang, Zeyu, Han, Yijia, Zhang, Xiaotuan, Sun, Yao, Lin, Yuzhan, Feng, Luozhu, Zhou, Tieli, Wang, Zhongyong   +7 more
openaire   +1 more source

Rapid detection of ceftazidime/avibactam resistance by MALDI-TOF MS [PDF]

Journal of Antimicrobial Chemotherapy, 2018
Cecilia Godoy, Carvalhaes, Ana Carolina, Ramos, Lilian Caroline Gonçalves de, Oliveira, Maria Aparecida, Juliano, Ana Cristina, Gales   +4 more
openaire   +2 more sources

Antibiotic Susceptibility of Aerobic and Facultative Anaerobic Gram-Negative Rods in Hong Kong and Implications on Usefulness of Ceftazidime-Avibactam and Ceftolozane-Tazobactam

Antibiotics
Due to the increasing resistance of aerobic and facultative anaerobic Gram-negative rods, ceftazidime-avibactam and ceftolozane-tazobactam have been launched in the market in the last few years.
Jade L. L. Teng, Elaine Chan, Tsz Tuen Li, Tsz Ying Kwan, Ka Fai Chan, Wing Ho Li, Viki W. K. Tang, Man Lung Yeung, Susanna K. P. Lau, Patrick C. Y. Woo   +9 more
doaj   +1 more source

Ceftazidime/Avibactam and Other Commonly Used Antibiotics Activity Against Enterobacterales and Pseudomonas aeruginosa Isolated in Poland in 2015–2019

Infection and Drug Resistance, 2022
Patrycja Zalas-Więcek,1 Małgorzata Prażyńska,1 Łukasz Pojnar,2 Anna Pałka,2 Dorota Żabicka,3 Monika Orczykowska-Kotyna,3 Aleksandra Polak,3 Barbara Możejko-Pastewka,4 Ewa Anna Głowacka,4 Izabela ...
Zalas-Więcek P, Prażyńska M, Pojnar Ł, Pałka A, Żabicka D, Orczykowska-Kotyna M, Polak A, Możejko-Pastewka B, Głowacka EA, Pieniążek I, Pawlik M, Grys M, Bogiel M   +12 more
doaj  

Additional file 2 of Acetylcysteine increases sensitivity of ceftazidime-avibactam–resistant enterobacterales with different enzymatic resistance to ceftazidime-avibactam in vitro and in vivo

Additional file 2: Figure S2. ROS measurements of CZA-resistant DC7914, CG1090, and FK7018 after various treatments.
Huang, Zeyu, Han, Yijia, Zhang, Xiaotuan, Sun, Yao, Lin, Yuzhan, Feng, Luozhu, Zhou, Tieli, Wang, Zhongyong   +7 more
openaire   +1 more source