Results 11 to 20 of about 105,631 (265)

Antimicrobial Resistance Profiles of Pseudomonas aeruginosa in a Korean Community Hospital: In Vitro Activity of Ceftazidime-Avibactam and Other Agents [PDF]

Polish Journal of Microbiology
The novel antibiotic ceftazidime-avibactam was introduced in Korea in 2023. This study evaluated the in vitro susceptibility of Pseudomonas aeruginosa isolates from a community-based hospital to various antibiotics, including ceftazidime-avibactam.
Lee Hyo-Jin, Cho Sung-Yeon, Lee Dong-Gun, Park Chulmin, Byun Jihyun, Chun Hye-Sun, Kim Yang Ree   +6 more
doaj   +2 more sources

Impact of a Rapid Molecular Test for Klebsiella pneumoniae Carbapenemase and Ceftazidime-Avibactam Use on Outcomes after Bacteremia Caused by Carbapenem-Resistant Enterobacterales.

Clinical Infectious Diseases, 2022
BACKGROUND Patients with bacteremia due to carbapenem-resistant Enterobacterales (CRE) experience delays until appropriate therapy and high mortality rates.
M. Satlin, Liang Chen, A. Gomez-Simmonds, Jamie Marino, G. Weston, T. Bhowmick, S. Seo, S. Sperber, A. Kim, Brandon Eilertson, Sierra Derti, S. Jenkins, M. Levi, M. Weinstein, Yi-Wei Tang, T. Hong, S. Juretschko, K. Hoffman, T. Walsh, L. Westblade, A. Uhlemann, Barry N. Kreiswirth   +21 more
semanticscholar   +1 more source

Antibacterial Susceptibility Pattern of S. maltophilia Isolates at A Tertiary Care Hospital, India

Journal of Pure and Applied Microbiology, 2023
A sudden emergence of Stenotrophomonas maltophilia as a primary pathogen both in immunocompromised and immunocompetent individuals has raised a serious concern, as it is associated with significant case fatality ratio.
Mohammed Ashraf Ali Namaji, Muzafar Ahmad Bhat, Manas Dixit, Sanjay Pratap Singh, Raghavendra Huchchannavar   +4 more
doaj   +1 more source

Structural Characterization of the D179N and D179Y Variants of KPC-2 β-Lactamase: Ω-Loop Destabilization as a Mechanism of Resistance to Ceftazidime-Avibactam

Antimicrobial Agents and Chemotherapy, 2022
Klebsiella pneumoniae carbapenemases (KPC-2 and KPC-3) present a global clinical threat, as these β-lactamases confer resistance to carbapenems and oxyimino-cephalosporins.
T. A. Alsenani, S. Viviani, V. Kumar, M. Taracila, C. Bethel, M. D. Barnes, K. Papp-Wallace, R. Shields, M. Nguyen, C. Clancy, R. Bonomo, F. van den Akker   +11 more
semanticscholar   +1 more source

Feasibility, Effectiveness and Safety of Elastomeric Pumps for Delivery of Antibiotics to Adult Hospital Inpatients—A Systematic Review

Antibiotics, 2023
Elastomeric infusion pumps (EMPs) have been implemented in many fields, including analgesia, chemotherapy and cardiology. Their application in antimicrobials is mainly limited to the outpatient setting, but with a need to optimise inpatient antimicrobial
Joseph Spencer-Jones, Timothy Luxton, Stuart E. Bond, Jonathan Sandoe   +3 more
doaj   +1 more source

Multiple Novel Ceftazidime-Avibactam-Resistant Variants of blaKPC-2-Positive Klebsiella pneumoniae in Two Patients

Microbiology spectrum, 2022
Carbapenem-resistant K. pneumoniae which was classified as the most urgent threat by World Health Organization, is the most critical public health concern due to its high mortality rate.
Qingyu Shi, Renru Han, Yan Guo, Yang Yang, Shiann-Ching Wu, Li Ding, Rong Zhang, D. Yin, F. Hu   +8 more
semanticscholar   +1 more source

Antimicrobial Effect of Zinc Oxide Nanoparticles against Multidrug-Resistant Acinetobacter baumannii

Journal of Medical Microbiology and Infectious Diseases, 2023
Introduction: Increased multidrug-resistant (MDR) Acinetobacter baumannii (A. baumannii) infections pose a significant challenge in hospital settings.
Nader Mashayekh1, Leila Modiri1*, Masood Ghane2, Yousef Erfani3   +3 more
doaj   +1 more source

Bacterial membrane vesicles from Acinetobacter baumannii induced by ceftazidime are more virulent than those induced by imipenem

Virulence, 2020
Patients with Acinetobacter baumannii bacteremia treated with antipseudomonal cephalosporins showed higher 14-day mortality than patients treated with antipseudomonal carbapenems.
Chun-Hsiang Chiu, Yi-Tzu Lee, Yu-Chun Lin, Shu-Chen Kuo, Ya-Sung Yang, Yung-Chih Wang, Yu-Han Liu, Jung-Chung Lin, Feng-Yee Chang, Te-Li Chen   +9 more
doaj   +1 more source

Ceftazidime-Avibactam for the Treatment of Serious Gram-Negative Infections with Limited Treatment Options: A Systematic Literature Review

Infectious Disease and Therapy, 2021
A systematic literature review was undertaken to evaluate real-world use of ceftazidime-avibactam for infections due to aerobic Gram-negative organisms in adults with limited treatment options. Literature searches retrieved peer-reviewed publications and
Á. Soriano, Y. Carmeli, A. Omrani, Luke S.P. Moore, M. Tawadrous, P. Irani   +5 more
semanticscholar   +1 more source

BETTER OUTCOME OF HIGH-DOSE CEFTAZIDIME IN HEMATO – ONCOLOGICAL PATIENTS WITH INFECTIONS CAUSED BY EXTENSIVELY DRUG-RESISTANT PSEUDOMONAS AERUGINOSA

Mediterranean Journal of Hematology and Infectious Diseases, 2022
Background: P. aeruginosa sepsis in immunocompromised patients is serious complication of cancer treatment, especially in case of XDR pathogen. The purpose of the study is to evaluate the efficacy of high-dose ceftazidime in treatment of XDR P ...
Alzbeta Zavrelova, Jakub Radocha, Pavla Paterova, Pavel Zak, Benjamin Visek, Martin Sima   +5 more
doaj   +1 more source