Latar belakang. Terapi antibiotik empiris spektrum luas merupakan standar pengobatan demam neutropenia pada keganasan karena morbiditas dan mortalitas yang berhubungan dengan sepsis bakterial.
Agustinus William +3 more
doaj +2 more sources
Interactions between Avibactam and Ceftazidime-Hydrolyzing Class D β-Lactamases [PDF]
Class D β-lactamases exhibit very heterogeneous hydrolysis activity spectra against the various types of clinically useful β-lactams. Similarly, and according to the available data, their sensitivities to inactivation by avibactam can vary by a
Jean-Marie Frère +6 more
doaj +2 more sources
Ceftazidime resistance in Pseudomonas aeruginosa is multigenic and complex.
Pseudomonas aeruginosa causes a wide range of severe infections. Ceftazidime, a cephalosporin, is a key antibiotic for treating infections but a significant proportion of isolates are ceftazidime-resistant.
Winstanley, Craig +15 more
core +1 more source
Ceftazidime: pharmacokinetics in young volunteers versus elderly patients and therapeutic efficacy with complicated urinary tract infections [PDF]
Thirty-six urological patients (21 male, 15 female) aged 21 to 83 years with complicated and/or hospital-acquired urinary tract infections due to sensitive bacteria were treated with ceftazidime intravenously with a daily dose of 2 g bd over 5 to 17 days.
Kurt G. Naber +5 more
core +1 more source
Microbiological assay for ceftazidime injection
A simple, sensitive, and specific biodiffusion assay for the! antibacterial ceftazidime was developed using a strain of Staphylococcus epidermidis (ATCC 12228) as the test organism.
Salgado, Hérida Regina Nunes +1 more
core +4 more sources
The increase in nosocomial infections by beta-lactamase producing Gram-negative bacilli constitutes a therapeutic challenge. The combination of ceftazidime-avibactam offers a very interesting therapeutic option for nosocomial pneumonia caused by extended-spectrum beta-lactamase-producing Klebsiella pneumoniae, multidrug-resistant Pseudomonas aeruginosa,
openaire +2 more sources
Hydrolysis of cefazolin by enzymes produced by Pseudomonas aeruginosa after exposure to ceftazidime in vitro [PDF]
Background/Aim. Sometimes resistance of Pseudomonas aeruginosa (Ps. aeruginosa) is developed during antibiotic treatment, in spite of the initial susceptibility in vitro. The aim of this study was to use an in vitro model for the study of the development
Papaioannidou Paraskevi +2 more
doaj +1 more source
Cefdinir binding to a class A β-lactamase revealed by serial cryo-crystallography. [PDF]
Serial cryo‐crystallography reveals the structure of the extended‐spectrum β‐lactamase CTX‐M‐14 in complex with the third‐generation cephalosporin antibiotic cefdinir.One of the most common resistance mechanisms against antibiotics employed by Gram‐negative bacteria involves the production of β‐lactamases, resulting in rapid hydrolysis of the ...
Gore G +4 more
europepmc +2 more sources
Poly(styrene-alt-maleic anhydride) Conjugated with Spermine: Synthesis, Antibacterial Activity and Antibiotic Susceptibility [PDF]
Hypothesis: In the past decades, the increasing resistance to antibiotics among some nosocomial infection pathogens has been one of the largest challenges of human health. One of the ways to reduce antibiotic resistance in bacteria is the combination use
Jalil Javedani Bafekr +3 more
doaj +1 more source
In silico ADME and Toxicity Prediction of Ceftazidime and Its Impurities
To improve the quality control of drugs, we predicted the absorption, distribution, metabolism, excretion, and toxicity (ADMET) of ceftazidime (CAZ) and its impurities via in silico methods.
Ying Han +5 more
doaj +1 more source

