Results 31 to 40 of about 50,777 (219)

Genistein Exposure Interferes with Pharmacokinetics of Celecoxib in SD Male Rats by UPLC-MS/MS

Biochemistry Research International, 2017
Objective. To discuss the effects of genistein on the metabolism of celecoxib in vitro and in vivo. Method. In vitro, the effects of genistein on the metabolism of celecoxib were studied using rat and human liver microsomes.
Xiang Zheng, Jian Wen, Teng-hui Liu, Qiu-Geng Ou-yang, Jian-ping Cai, Hong-yu Zhou   +5 more
doaj   +1 more source

Metronomic Celecoxib Therapy in Clinically Available Dosage Ablates Hepatocellular Carcinoma via Suppressing Cell Invasion, Growth, and Stemness in Pre-Clinical Models

Frontiers in Oncology, 2020
ObjectiveTo investigate the anti-carcinogenic effect of metronomic Celecoxib (i.e., frequent administration in clinically available doses) against hepatocellular carcinoma (HCC) in the perspective of metastasis, spontaneous hepatocarcinogenesis, cancer ...
Chun-Chieh Yeh, Chun-Chieh Yeh, Pei-Ying Liao, Pei-Ying Liao, Sudhir Pandey, Su-Yung Yung, Hsueh-Chou Lai, Hsueh-Chou Lai, Long-Bin Jeng, Long-Bin Jeng, Wei-Chun Chang, Wei-Chun Chang, Wen-Lung Ma, Wen-Lung Ma, Wen-Lung Ma, Wen-Lung Ma   +15 more
doaj   +1 more source

Celecoxib exhibits therapeutic potential in experimental model of hyperlipidaemia.

PLoS ONE, 2021
Hyperlipidaemia is a major risk factor for cardiovascular diseases, the leading cause of death globally. Celecoxib attenuated hypercholesterolaemia associated with CCl4-induced hepatic injury in rats without improving liver function in our previous study.
Martins Ekor, Phyllis Elsie Owusu Agyei, Ernest Obese, Robert Peter Biney, Isaac Tabiri Henneh, Meshack Antwi-Adjei, Ewura Seidu Yahaya, Gordon Amoakohene, Patrick Kafui Akakpo   +8 more
doaj   +1 more source

The RCSB Protein Data Bank: views of structural biology for basic and applied research and education. [PDF]

, 2014
The RCSB Protein Data Bank (RCSB PDB, http://www.rcsb.org) provides access to 3D structures of biological macromolecules and is one of the leading resources in biology and biomedicine worldwide.
Berman, Helen M, Bi, Chunxiao, Bluhm, Wolfgang F, Bourne, Philip E, Burley, Stephen K, Christie, Cole H, Dutta, Shuchismita, Goodsell, David S, Green, Rachel Kramer, Prlić, Andreas, Rose, Peter W, Westbrook, John D, Woo, Jesse, Young, Jasmine, Zardecki, Christine   +14 more
core   +4 more sources

Jitteriness/anxiety syndrome caused by coadministration of celecoxib, a selective COX‐2 inhibitor, with escitalopram and trazodone in a patient with depression and spondylolisthesis

Neuropsychopharmacology Reports, 2023
Antidepressant‐induced jitteriness/anxiety syndrome is characterized as anxiety, agitation, panic attacks, insomnia, irritability, hostility, aggressiveness, impulsivity, akathisia, and (hypo)mania, which appear immediately after initiation or increased ...
Toshinori Shirata, Shinji Yano, Keisuke Noto, Muneaki Kanno, Akihito Suzuki   +4 more
doaj   +1 more source

Use of Non-Steroidal Anti-Inflammatory Drugs That Elevate Cardiovascular Risk: An Examination of Sales and Essential Medicines Lists in Low-, Middle-, and High-Income Countries [PDF]

, 2013
PMCID: PMC3570554This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
A Dans, A Rostom, CP Cannon, D Henry, David Henry, E Masso Gonzalez, EL Fosbol, Fiona Mary Turnbull, JJ Deeks, JM Scheiman, L Garcia Rodriguez, P Kearney, P McGettigan, P McGettigan, Patricia McGettigan, S Hernandez-Dıaz, S Singh, S Trelle, SL Collins, T Grosser, V Strand   +20 more
core   +3 more sources

Clinical Efficacy of Celecoxib with and without Caffeine versus Ibuprofen for Pain Control following Crown Lengthening Surgery

Journal of Dental School, 2019
Objective: Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed pain control medications following periodontal surgery. This study aimed to compare the efficacy of three drug regimens namely celecoxib, celecoxib + caffeine and
Niloofar Jenabian, Ali Akbar Moghadamnia, Reza Beyraghshamshir   +2 more
doaj   +1 more source

Advances in Preventive Therapy for Estrogen-Receptor-Negative Breast Cancer. [PDF]

, 2014
Preventing breast cancer is an effective strategy for reducing breast cancer deaths. The purpose of chemoprevention (also termed preventive therapy) is to reduce cancer incidence by use of natural, synthetic, or biological agents.
Brown, Powel H, Litzenburger, Beate C
core   +1 more source

Cytokinesis-block micronucleus assay of celecoxib and celecoxib derivatives

Toxicology Reports, 2020
Celecoxib is used widely for the acute treatment of pain and for pain relief in various diseases. Furthermore, it shows potential in chemoprevention, although chronic treatment with celecoxib could lead to adverse effects like cardiovascular events.
Hauke Reimann, Quoc Anh Ngo, Helga Stopper, Henning Hintzsche   +3 more
doaj   +1 more source

Herbal therapy for treating rheumatoid arthritis (review) [PDF]

, 2011
Background Herbal medicine interventions have been identified as having potential benefit in the treatment of rheumatoid arthritis (RA). Objectives To update an existing systematic (Cochrane) review of herbal therapies in RA. Search methods
Cameron, Melainie, Chrubasik, Sigrun, Gagnier, Joel J.   +2 more
core   +1 more source