Results 31 to 40 of about 58,334 (260)

Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis [PDF]

open access: yes, 2006
The use of cyclo-oxygenase 2 selective nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with increased risk of acute myocardial infarction (AMI). The association between the risks of AMI with nonselective NSAIDs is less clear.
Langhorne, P.   +3 more
core   +2 more sources

Advances in Preventive Therapy for Estrogen-Receptor-Negative Breast Cancer. [PDF]

open access: yes, 2014
Preventing breast cancer is an effective strategy for reducing breast cancer deaths. The purpose of chemoprevention (also termed preventive therapy) is to reduce cancer incidence by use of natural, synthetic, or biological agents.
Brown, Powel H, Litzenburger, Beate C
core   +1 more source

Formulation, Characterization, and in Vivo Evaluation of Celecoxib-PVP Solid Dispersion Nanoparticles Using Supercritical Antisolvent Process

open access: yesMolecules, 2014
The aim of this study was to develop celecoxib-polyvinylpyrrolidone (PVP) solid dispersion nanoparticles with and without surfactant using the supercritical antisolvent (SAS) process.
Eun-Sol Ha   +3 more
doaj   +1 more source

Cytokinesis-block micronucleus assay of celecoxib and celecoxib derivatives

open access: yesToxicology Reports, 2020
Celecoxib is used widely for the acute treatment of pain and for pain relief in various diseases. Furthermore, it shows potential in chemoprevention, although chronic treatment with celecoxib could lead to adverse effects like cardiovascular events.
Hauke Reimann   +3 more
doaj   +1 more source

Herbal therapy for treating rheumatoid arthritis (review) [PDF]

open access: yes, 2011
Background Herbal medicine interventions have been identified as having potential benefit in the treatment of rheumatoid arthritis (RA). Objectives To update an existing systematic (Cochrane) review of herbal therapies in RA. Search methods
Cameron, Melainie   +2 more
core   +1 more source

Evaluation of Celecoxib-Lactose Incompatibility Reactions at Solid State using Physicochemical Methods [PDF]

open access: yesJournal of Research in Applied and Basic Medical Sciences, 2021
Background & Aims:  Drug excipient incompatibility evaluation is an important part of pre-formulation studies. Drug-excipient interaction may affect drug stability, bioavailability, therapeutic effects, efficacy, and safety.
Ali Fattahzadeh   +3 more
doaj  

Selective Cyclooxygenase-2 Inhibitor Prevents Cisplatin-induced Tumorigenesis in A/J Mice [PDF]

open access: yes, 2012
Cisplatin is used to treat lung cancer;however, it is also a known carcinogen. Cyclooxygenase-2 (COX-2) inhibitors have been shown to prevent carcinogen-induced experimental tumors. We investigated the effect of a COX-2 inhibitor, celecoxib, on cisplatin-
Katayama, Hideki   +9 more
core   +1 more source

The Effect of Lower-Limb Exercise on Pain Management of the Patients Undergoing Posterior Lumbar Fusion Surgery: A Retrospective Case-Control Study

open access: yesPain Research and Management, 2021
Purpose. The purpose of this study is to investigate the clinical effect of lower-limb exercise, when combined with celecoxib, on pain management of patients undergoing posterior lumbar fusion surgeries. Methods.
Tong Wu, Yong Ye
doaj   +1 more source

Differential pharmacokinetics and pharmacokinetic/pharmacodynamic modelling of robenacoxib and ketoprofen in a feline model of inflammation [PDF]

open access: yes, 2014
Robenacoxib and ketoprofen are acidic nonsteroidal anti‐inflammatory drugs (NSAIDs). Both are licensed for once daily administration in the cat, despite having short blood half‐lives.
Arifah   +48 more
core   +3 more sources

Celecoxib Enhances Radiosensitivity via Induction of G2-M Phase Arrest and Apoptosis in Nasopharyngeal Carcinoma

open access: yesCellular Physiology and Biochemistry, 2014
Background: Previous work has proposed that celecoxib may be able to enhance the effects of radiotherapy. However, the underlying mechanism of this activity has not yet been determined.
Shui-xing Zhang   +4 more
doaj   +1 more source

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