Results 11 to 20 of about 33,756 (203)

Cytokinesis-block micronucleus assay of celecoxib and celecoxib derivatives

open access: yesToxicology Reports, 2020
Celecoxib is used widely for the acute treatment of pain and for pain relief in various diseases. Furthermore, it shows potential in chemoprevention, although chronic treatment with celecoxib could lead to adverse effects like cardiovascular events.
Hauke Reimann   +3 more
doaj   +2 more sources

Celecoxib coupled to dextran via a glutamic acid linker yields a polymeric prodrug suitable for colonic delivery

open access: yesDrug Design, Development and Therapy, 2015
Yonghyun Lee,1,2,* Jungyun Kim,1,* Wooseong Kim,1,* Joon Nam,1,* Seongkeun Jeong,1 Sunyoung Lee,1 Jin-Wook Yoo,1 Min-Soo Kim,1 Yunjin Jung1 1College of Pharmacy, Pusan National University, Busan, 2Bio-Nanomedicine Laboratory, Department of Biological ...
Lee Y   +8 more
doaj   +1 more source

Safety of celecoxib versus traditional nonsteroidal anti-inflammatory drugs in older patients with arthritis

open access: yesJournal of Pain Research, 2018
Sooyoung Shin1,2 1Department of Clinical Pharmacy, College of Pharmacy, Ajou University, Yeongtong-gu, Suwon, Republic of Korea; 2Research Institute of Pharmaceutical Science and Technology (RIPST), Ajou University, Yeongtong-gu, Suwon, Republic of Korea
Shin S
doaj   +1 more source

Efectos renales de los inhibidores selectivos de la ciclooxigenasa-2 (COX-2) en la cirrosis. Estudios "in vivo" en ratas inducidas a cirrosis y estudios "in vitro" en células mesangiales. [PDF]

open access: yes, 2006
[spa] En la cirrosis descompensada, la síntesis renal de prostaglandinas (PGs), juega un papel clave en el mantenimiento de la función renal. En concreto, las PGs renales contrarrestan la exacerbada actividad vasoconstrictora asociada a la activación de ...
López Parra, Marta
core   +6 more sources

Inhibitory effect of celecoxib on agomelatine metabolism in vitro and in vivo

open access: yesDrug Design, Development and Therapy, 2018
Jiayang He,1 Ping Fang,2 Xiang Zheng,2 Chenchen Wang,2 Tenghui Liu,2 Bowen Zhang,2 Jian Wen,2 Ren-ai Xu3 1Department of Pharmacy, The First Hospital of Jiaxing, Jiaxing, Zhejiang, China; 2Department of Pharmacology, School of Pharmacy of Wenzhou Medical
He JY   +7 more
doaj   +1 more source

The Cost-effectiveness of Celecoxib versus Non-steroidal Anti-inflammatory Drugs plus Proton-pump Inhibitors for Treating Osteoarthritis in Algeria [PDF]

open access: yesJournal of Health Economics and Outcomes Research, 2013
# Background Cyclooxygenase-2 inhibitors such as celecoxib are as effective as non-selective non-steroidal anti-inflammatory drugs (ns-NSAIDs) in the treatment of osteoarthritis (OA), have fewer gastrointestinal side effects, but are more expensive ...
Nadir Hammoumraoui   +3 more
doaj   +1 more source

Evaluation of glycine-bearing celecoxib derivatives as a colon-specific mutual prodrug acting on nuclear factor-κB, an anti-inflammatory target

open access: yesDrug Design, Development and Therapy, 2015
Sunyoung Lee,1,* Yonghyun Lee,1,2,* Wooseong Kim,1 Joon Nam,1 Seongkeun Jeong,1 Jin-Wook Yoo,1 Min-Soo Kim,1 Hyung Ryong Moon,1 Yunjin Jung11College of Pharmacy, Pusan National University, Busan, 2Bio-Nanomedicine Lab, Department of Biological Sciences ...
Lee S   +8 more
doaj   +1 more source

Celecoxib for osteoarthritis [PDF]

open access: yesCochrane Database of Systematic Reviews, 2017
Osteoarthritis (OA) is the most common form of arthritis and is caused by degeneration of the joint cartilage and growth of new bone, cartilage and connective tissue. It is often associated with major disability and impaired quality of life. There is currently no consensus on the best treatment to improve OA symptoms.
Livia, Puljak   +5 more
openaire   +2 more sources

Down-regulation of glucose-regulated protein (GRP) 78 potentiates cytotoxic effect of celecoxib in human urothelial carcinoma cells. [PDF]

open access: yesPLoS ONE, 2012
Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor that has been reported to elicit anti-proliferative response in various tumors. In this study, we aim to investigate the antitumor effect of celecoxib on urothelial carcinoma (UC) cells and the ...
Kuo-How Huang   +8 more
doaj   +1 more source

The Efficacy and Safety of Celecoxib in Addition to Standard Cancer Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

open access: yesCurrent Oncology, 2022
The purpose of this meta-analysis was to evaluate the efficacy and safety of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, in addition to standard anticancer therapy. Randomized controlled trials (RCTs) that evaluated the efficacy and safety
Shi-Yu Ye   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy