Results 21 to 30 of about 25,572 (179)
Celecoxib exhibits therapeutic potential in experimental model of hyperlipidaemia.
PLoS ONE, 2021 Hyperlipidaemia is a major risk factor for cardiovascular diseases, the leading cause of death globally. Celecoxib attenuated hypercholesterolaemia associated with CCl4-induced hepatic injury in rats without improving liver function in our previous study.
Martins Ekor +8 more
doaj +1 more source
N‐Alkoxysulfurdiimide Reagents for the One‐Step Modular Synthesis of Primary Sulfonimidamides
Angewandte Chemie, EarlyView.N‐Alkoxysulfurdiimide reagents when combined with organometallic reagents lead directly to primary sulfonimidamide products. The reactions are broad in scope, encompassing aryl, heteroaryl, and alkyl carbon substituents. The reactivity of the N‐alkoxysulfurdiimide reagents can be correlated with the electron‐withdrawing ability of the N‐substituent ...
Suzanne E. Davison +6 more
wiley +2 more sources
The Professional Medical Journal, 2018 Objective: To observe the absolute, relative weight of kidney and body weightof albino rats on celecoxib induced kidney with protection by lycopene. Study Design:Experimental study. Place and Duration of study: This study was conducted in BMSI (Anatomydepartment), JPMC, Karachi, from 4th May 2015 to 3rd June 2015.
Sadia Sundus +3 more
openaire +3 more sources
Journal of Dental School, 2019 Objective: Non-steroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed pain control medications following periodontal surgery. This study aimed to compare the efficacy of three drug regimens namely celecoxib, celecoxib + caffeine and
Niloofar Jenabian +2 more
doaj +1 more source
Pakistan Journal of Pharmaceutical Sciences, 2020 Celecoxib, a selective COX-2 inhibitor, is one of the most effective and widely used analgesic and anti-inflammatory drugs. However it has been reported that celecoxib may cause adverse effects on liver, kidney and GIT.
Maria Khan +6 more
doaj +1 more source
Cytokinesis-block micronucleus assay of celecoxib and celecoxib derivatives
Toxicology Reports, 2020 Celecoxib is used widely for the acute treatment of pain and for pain relief in various diseases. Furthermore, it shows potential in chemoprevention, although chronic treatment with celecoxib could lead to adverse effects like cardiovascular events.
Hauke Reimann +3 more
doaj +1 more source
Pain Research and Management, 2021 Purpose. The purpose of this study is to investigate the clinical effect of lower-limb exercise, when combined with celecoxib, on pain management of patients undergoing posterior lumbar fusion surgeries. Methods.
Tong Wu, Yong Ye
doaj +1 more source
Molecules, 2014 The aim of this study was to develop celecoxib-polyvinylpyrrolidone (PVP) solid dispersion nanoparticles with and without surfactant using the supercritical antisolvent (SAS) process.
Eun-Sol Ha +3 more
doaj +1 more source
Evaluation of Celecoxib-Lactose Incompatibility Reactions at Solid State using Physicochemical Methods [PDF]
Journal of Research in Applied and Basic Medical Sciences, 2021 Background & Aims: Drug excipient incompatibility evaluation is an important part of pre-formulation studies. Drug-excipient interaction may affect drug stability, bioavailability, therapeutic effects, efficacy, and safety.
Ali Fattahzadeh +3 more
doaj
Advanced Science, EarlyView.ABSTRACT Osteoarthritis (OA) is a widespread degenerative joint condition marked by progressive cartilage breakdown, and a chronic inflammatory microenvironment, where conventional therapies largely fail to halt disease progression. To address this unmet need, an intra‐articularly implantable, disease‐responsive scaffold was developed for combinatorial
Zhen Zhang +6 more
wiley +1 more source