Results 91 to 100 of about 76,985 (253)

Peptic ulcer disease: Insights and risk factors

JPGN Reports, EarlyView.
Abstract Objectives Peptic ulcer disease (PUD), affects adults and children, with Helicobacter pylori (H. pylori) infection being the most frequent cause. Diagnosis requires an upper gastrointestinal endoscopy (UGE) and invasive tests. However, besides H. pylori, risk factors for PUD in children remain unclear.
Haidar Houmani, Islam Saidi, Meline M'rini, Julie Nguyen, Assaad Salame, Patrick Bontems, Kallirroi Kotilea   +6 more
wiley   +1 more source

Understanding youth preferences for a mentorship program for celiac disease: A qualitative study

JPGN Reports, EarlyView.
Abstract Objective Celiac disease (CeD) is an autoimmune condition triggered by gluten ingestion that causes intestinal inflammation and multiple symptoms. Management requires strict adherence to a gluten‐free diet (GFD), yet youth with CeD on a GFD report lower quality of life (QoL) and higher rates of depression and anxiety.
Ashley L. Dunn, Parnia Abrishamchian, Ally Koh, Garret Forshee, Jennifer Iscol, Anava Wren, Hilary Jericho   +6 more
wiley   +1 more source

Gastric duplication cyst causing hypergastrinemia in an infant

JPGN Reports, EarlyView.
Abstract Gastric duplication cysts are rare congenital anomalies, with fewer than 10% occurring in the stomach. We report a 14‐month‐old girl presenting with failure to thrive, recurrent emesis, hematemesis, and severe duodenitis with ulceration. Laboratory evaluation revealed marked hypergastrinemia (1781 pg/mL), and initial imaging was unrevealing ...
Nathan Bryan, Ian Leibowitz
wiley   +1 more source

Impact of cystic fibrosis transmembrane conductance regulator modulator therapies on liver stiffness and liver enzymes: An observational perspective single‐center cohort study

JPGN Reports, EarlyView.
Abstract Objectives The efficacy of cystic fibrosis transmembrane conductance regulator (CFTR)‐modulator therapies in preventing or ameliorating cystic fibrosis liver disease (CFLD) by correcting CFTR in cholangiocytes is not well‐documented. This study aimed to assess liver function during CFTR‐modulators.
Laura Giugliano, Elisabetta Augustoni, Antonio Pizzol, Anna Opramolla, Cristina Chiadò, Anna Zagaria, Irene Esposito, Giulia Roberto, Alice Ponte, Andrea Evangelista, Paola Quarello, Michele Pinon, Pier Luigi Calvo   +12 more
wiley   +1 more source

Delayed diagnosis of hereditary fructose intolerance presenting as chronic lean steatosis in an adolescent

JPGN Reports, EarlyView.
Abstract Hereditary fructose intolerance (HFI) typically presents in infancy with acute metabolic crisis upon the introduction of fructose. We report a case of a 13‐year‐old female with chronic abdominal pain, short stature, and persistent mild transaminitis.
Alexandra Hurlock, Melissa Lah, Hannah Sue Hyaduck, Jean P. Molleston, Chaowapong Jarasvaraparn   +4 more
wiley   +1 more source

Complementary and alternative medicine use by patients in pediatric gastroenterology clinics

JPGN Reports, EarlyView.
Abstract Objectives Use of complementary and alternative medicine (CAM) therapies among children seen in pediatric gastroenterology (GI) clinics is high. Multiple CAM therapies are effective as primary and adjuvant therapies for GI disorders and symptoms. Our study aimed to define the historical use of CAM and interest in CAM therapies in a specialized
Joshua D. Prozialeck, Lauren M. Potthoff, Bridget Whitehead, John E. Fortunato   +3 more
wiley   +1 more source

A hepatic enigma: Pediatric presentation of primary biliary cholangitis

JPGN Reports, EarlyView.
Abstract Primary biliary cholangitis (PBC) is a chronic autoimmune condition characterized by destruction of intrahepatic bile ducts, leading to fibrosis and cirrhosis of the liver. It is an extremely rare pediatric disease with very few pediatric cases reported to date. Here, we report the case of a 14‐year‐old female who presented with elevated liver
Sindhura Kasturi, Rachel Schenker, Nick Shillingford, George Yanni   +3 more
wiley   +1 more source

Endoscopic findings in patients with Shwachman–Diamond syndrome: A report from the North American Shwachman–Diamond syndrome registry

JPGN Reports, EarlyView.
Abstract Objectives Shwachman–Diamond syndrome (SDS) is an inherited bone marrow failure disorder, and its endoscopic phenotype is poorly defined. We sought to characterize endoscopic findings in patients with genetically confirmed SDS. Methods Retrospective registry study of 45 patients with biallelic Shwachman–Bodian–Diamond syndrome mutations and ...
Elizabeth Korn, Jane Koo, Diana Schwarz, Meghan Haney, Juan Putra, Jaeson Kim, Leah Cheng, Sarah Steltz, Lois Schwarz, Sara Loveless, Richard Cooper, Claire Dusa, Kasiani C. Myers, Akiko Shimamura, Andrew Wehrman, Amit S. Grover   +15 more
wiley   +1 more source

Expression of M30 and M65 in celiac disease. Analytical cross-sectional study

São Paulo Medical Journal
BACKGROUND: The role of villous atrophy in apoptosis, a distinctive feature of celiac disease, is a matter of controversy. The aim of this study was to determine the apoptosis rate through immunohistochemical staining for M30 and M65 in celiac disease ...
Evrim Kahramanoğlu Aksoy, Gülçin Güler Şimşek, Murat Torgutalp, Ferdane Pirinççi Sapmaz, Muhammet Yener Akpınar, Metin Uzman, Yaşar Nazlıgül   +6 more
doaj   +1 more source

Use of single‐use ultra‐slim endoscopes for evaluation of pediatric esophageal varices: A pilot feasibility study

JPGN Reports, EarlyView.
ABSTRACT Esophageal varices (EV) need monitoring in patients with portal hypertension. In 2022, a single‐use ultra‐slim (3.5 mm) gastroscope was approved for use in children and adults. This study evaluated if an ultra‐slim gastroscope could evaluate, grade, and corroborate the presence of EV in sedated pediatric patients as compared to standard oral ...
Vishruti Patel, Evan Greenhall, Eric Dybbro, Sheetal Wadera, Joel A. Friedlander, Shauna Schroeder, Paul Tran   +6 more
wiley   +1 more source