Results 41 to 50 of about 15,097,095 (292)
Tumor Biology, 2017 Head and neck squamous cell carcinoma is the most commonly diagnosed cancer worldwide. The lifestyle, food habits, and customary practices manifest the Northeast Indian population toward higher susceptibility to develop head and neck squamous cell ...
Manish Kumar +7 more
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Circulating biomarkers to monitor cancer progression and treatment
Computational and Structural Biotechnology Journal, 2016 Tumor heterogeneity is a major challenge and the root cause of resistance to treatment. Still, the standard diagnostic approach relies on the analysis of a single tumor sample from a local or metastatic site that is obtained at a given time point. Due to
Suthee Rapisuwon +2 more
doaj +1 more source
, 2018 Obstetrical Care Provider Survey. This file contains the sample survey which we sent to obstetrical care providers exploring their knowledge and attitudes towards cell-free DNA screening. This document includes both English and French versions (DOCX 119 kb)
Chan, Wilson +3 more
openaire +1 more source
Epigenetic analysis of cell-free DNA by fragmentomic profiling
Proceedings of the National Academy of Sciences of the United States of America, 2022 Significance Cell-free DNA (cfDNA) is nonrandomly fragmented and contains a wealth of molecular information useful for noninvasive prenatal testing and cancer detection.
Qing Zhou +21 more
semanticscholar +1 more source
Comparison of methods for the quantification of cell-free DNA isolated from cell culture supernatant
Tumor Biology, 2019 Gaining a better understanding of the biological properties of cell-free DNA constitutes an important step in the development of clinically meaningful cell-free DNA–based tests.
Abel Jacobus Bronkhorst +2 more
doaj +1 more source
Fragmentation landscape of cell-free DNA revealed by deconvolutional analysis of end motifs
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance Cell-free DNA (cfDNA) fragmentation patterns carry a wealth of information related to DNA nuclease activities and tissues of origin. However, there is a lack of tools for obtaining a bird’s eye view of the involvement of nucleases and other ...
Ze Zhou +24 more
semanticscholar +1 more source
Study the Role of Cell Free DNA in the Diagnosis of Hepatocellular Carcinoma, an Egyptian Study
Asian Pacific Journal of Cancer Biology, 2022 Background and objective: Hepatocellular carcinoma (HCC) is a primary malignancy of the liver. Since the conventional tissue biopsy and AFP have limited value, a new promising diagnostic method” liquid biopsy” has emerged.
Noha Hassan Radwan +3 more
doaj +1 more source
High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants
Nature Medicine, 2019 Accurate identification of tumor-derived somatic variants in plasma circulating cell-free DNA (cfDNA) requires understanding of the various biological compartments contributing to the cfDNA pool.
P. Razavi +42 more
semanticscholar +1 more source
DNA methylation analysis explores the molecular basis of plasma cell-free DNA fragmentation
Nature Communications, 2023 Plasma cell-free DNA (cfDNA) are small molecules generated through a non-random fragmentation procedure. Despite commendable translational values in cancer liquid biopsy, however, the biology of cfDNA, especially the principles of cfDNA fragmentation ...
Yunyun An +13 more
semanticscholar +1 more source
Noninvasive prenatal diagnosis of fetal RhD status using cell-free fetal DNA in maternal plasma with TaqMan® real-time PCR assay [PDF]
, 2007 Prenatal diagnosis is now part of established obstetric practice in many countries. However, conventional methods of prenatal diagnosis of obtaining fetal tissues for genetic analysis, including amniocentesis and chorionic villus sampling, are invasive
Rekhviashvili, Tea
core +1 more source