Obstetrical Care Provider Survey. This file contains the sample survey which we sent to obstetrical care providers exploring their knowledge and attitudes towards cell-free DNA screening. This document includes both English and French versions (DOCX 119 kb)
Chan, Wilson +3 more
openaire +1 more source
Identifying a role for Ciz1 in the DNA damage response [PDF]
In proliferating cells, cell cycle arrest and DNA repair are induced upon detection of DNA damage. The DNA damage response (DDR) to double strand DNA breaks is mediated by phosphatidylinositol 3-kinase-like protein kinases (PIKKs), which propagate DDR ...
Roper, Katherine
core +3 more sources
In silico Design of Linear DNA for Robust Cell-Free Gene Expression
Cell-free gene expression systems with linear DNA expression templates (LDETs) have been widely applied in artificial cells, biochips, and high-throughput screening.
Xinjie Chen, Yuan Lu
doaj +1 more source
Noninvasive prenatal diagnosis of fetal RhD status using cell-free fetal DNA in maternal plasma with TaqMan® real-time PCR assay [PDF]
Prenatal diagnosis is now part of established obstetric practice in many countries. However, conventional methods of prenatal diagnosis of obtaining fetal tissues for genetic analysis, including amniocentesis and chorionic villus sampling, are invasive
Rekhviashvili, Tea
core +1 more source
Head and neck squamous cell carcinoma is the most commonly diagnosed cancer worldwide. The lifestyle, food habits, and customary practices manifest the Northeast Indian population toward higher susceptibility to develop head and neck squamous cell ...
Manish Kumar +7 more
doaj +1 more source
Biochemical and clinical diagnostic aspects of circulating nucleic acids [PDF]
We investigated the size distribution of fetal DNA using a combination of agorose gel electrophoresis, Southern blot and real time PCR assay. Our results showed plasma DNA presents apoptotic characteristics and the cell free fetal DNA is generally ...
Li, Ying
core +1 more source
The timing of the formation and usage of replicase clusters in S-phase nuclei of human diploid fibroblasts [PDF]
The sites of nascent DNA synthesis were compared with the distribution of the proliferating cell nuclear antigen (PCNA) in S-phase nuclei of human diploid fibroblasts (HDF) by two in vitro techniques.
Kill, IR +4 more
core +4 more sources
Specific antigen of tumor cell transformed by DNA extracted from SV-40 virus [PDF]
In the immunofluorescent study it has been revealed that rabbit sera immunized with transformed cells induced by SV-40 DNA, produce circulating antibody capable of re:lcting with intranuclear antigens synthesized by SV-40 complyte virus transforming ...
Okada, Shigeru +5 more
core +1 more source
Comparison of methods for the quantification of cell-free DNA isolated from cell culture supernatant
Gaining a better understanding of the biological properties of cell-free DNA constitutes an important step in the development of clinically meaningful cell-free DNA–based tests.
Abel Jacobus Bronkhorst +2 more
doaj +1 more source
Single Cell Analysis of Human RAD18-Dependent DNA Post-Replication Repair by Alkaline Bromodeoxyuridine Comet Assay [PDF]
Damage to DNA can block replication progression resulting in gaps in the newly synthesized DNA. Cells utilize a number of post-replication repair (PRR) mechanisms such as the RAD18 controlled translesion synthesis or template switching to overcome the ...
Himabindu Gali +14 more
core +2 more sources

