Results 201 to 210 of about 10,358,430 (239)

Using cell-free DNA tumor methylation score to detect and monitor cholangiocarcinoma. [PDF]

HPB (Oxford)
Javanshir S, Angeli-Pahim I, Iyengar P, Chambers A, Smarandache IM, Ganguli R, Shrestha A, Squadrito J, Abreu A, Suchan G, Rizk C, Palaz F, Hughes SJ, Sahin I, Grajo JR, Duarte S, Zarrinpar A.   +16 more
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Prognostic Significance of Cell-Free DNA Derived 5-Hydroxymethylcytosine Signatures in Newly Diagnosed Multiple Myeloma. [PDF]

JCO Precis Oncol
Zhang Z, Derman B, Wang B, Kowitwanich K, Cursio J, Gao L, Appelbaum D, He C, Jakubowiak A, Zhang W, Chiu BC.   +10 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

The emerging clinical relevance of cell-free DNA in lupus: from mechanistic insights to therapeutic opportunities. [PDF]

Front Immunol
Jones E, Cano-Gamez K.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Donor-derived cell-free DNA testing for noninvasive monitoring of allograft rejection after lung transplantation. [PDF]

Front Immunol
Ding S, Sun Y, Zheng X, Mai S, Wu J, Xu Y, Chen J, Huang M.   +7 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Preoperative cell-free DNA concentration in plasma as a diagnostic and prognostic biomarker of clear cell renal cell carcinoma

Contemporary Oncology
Tomasz Milecki, Katarzyna Kluzek, Natalia Pstrąg, Andrzej Antczak, Wojciech Cieślikowski, Mateusz Wichtowski, Łukasz Kuncman, Zbigniew Kwias, Joanna Wesoły   +8 more
doaj   +1 more source

Preoperative Plasma Cell-Free DNA Integrity Index in Clear Cell Renal Cell Carcinoma: An Exploratory Case-Control Study. [PDF]

Cancers (Basel)
Milecki T, Stępka J, Wesoły J, Cieślikowski WA.   +3 more
europepmc   +1 more source