Results 211 to 220 of about 10,358,430 (239)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Diagnostic accuracy of cell-free DNA-based non-invasive prenatal testing for fetal aneuploidies: a systematic review. [PDF]

Front Genet
Alhajlah S.
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Tumor-specific <i>KCNJ5</i> mutation in an aldosterone-producing adenoma not detected in adrenal venous plasma cell-free DNA. [PDF]

JCEM Case Rep
Aono D, Kato T, Kometani M, Yoneda T, Hosomichi K, Karashima S.   +5 more
europepmc   +1 more source

Global Hypomethylation in Cell-Free DNA Enables Noninvasive Colorectal Cancer Screening: Results from a Retrospective Validation Study. [PDF]

Comput Struct Biotechnol J
Kaur S, Lathwal S, Agrawal S, Mahmoudi T, Gupta S.   +4 more
europepmc   +1 more source

Microbial cell-free DNA for rapid pathogen identification in clinical diagnostics: a proof of concept study. [PDF]

Genome Med
Banz M, Hagel S, Freiburger S, Huhn F, Krause M, Glöckner S, Löffler B, Nurjadi D, Muthukumarasamy U, Jundzill M, Kaasch AJ, Pletz MW, Brandt C.   +12 more
europepmc   +1 more source

Development and preliminary validation of plasma cell-free DNA methylation-based diagnostic prediction model for colorectal cancer detection. [PDF]

J Gastrointest Oncol
Qu Y, Huang R, Chen Y, Xia P, Huang B, Liu J, Wu L, Zhang R, Wang Q.   +8 more
europepmc   +1 more source

Serum Cell-Free DNA as Predictor of Progression of Kidney Disease in Diabetes: A Single-Center Prospective Study. [PDF]

Indian J Endocrinol Metab
Majhi JK, Kumar PR, Dash DK, Patro D, Dhal BS, Dash B, Sahu PK.   +6 more
europepmc   +1 more source

Blood-based targeted sequencing of microbial cell-free DNA in severe pneumonia-associated sepsis. [PDF]

Respir Res
Huang H, Ye X, Gu D, Huang E, Yu X, Ai L, Deng J, Guo P, Liu H, Chen Y, Wang R, Luo Y, Chen P.   +12 more
europepmc   +1 more source

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Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions

Ca-A Cancer Journal for Clinicians, 2021
Heather A Parsons, Atish Choudhury, Michael L Cheng   +2 more
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