Results 221 to 230 of about 1,646,961 (327)

Biomaterials for Reproductive Restoration: Translating Engineering Innovations. [PDF]

Biomater Res
Yang C, Yoo HS.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

The effects of different cell-based therapies at a critical time point during the soft-tissue healing process

, 2018
Suman Jain, G Kiran
openalex   +1 more source

Stem Cell and Tissue-Based Therapies for Male Infertility [PDF]

, 2020
Sherin David
openalex  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Photodynamic therapy dosimetry: current status and the emerging challenge of immune stimulation. [PDF]

J Biomed Opt
Wilson BC, Lilge L, Weersink RA, Pires L.   +3 more
europepmc   +1 more source

New perspectives of tissue remodelling with neural stem and progenitor cell-based therapies

, 2012
Chiara Cossetti, Clara Alfaro‐Cervelló, Matteo Donegà, Giulia E. Tyzack, Stefano Pluchino   +4 more
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

The Effectiveness and Safety of Stem Cell-Based Tissue Engineering in the Regeneration of Periodontal Bone Lesions: A Systematic Review. [PDF]

Clin Pract
Fanid M, Vinhas AS, Reis C, Relvas M, Costa R, Cabral C.   +5 more
europepmc   +1 more source

Functionalized hydrogels and cell based therapies: A tissue engineering approach for spinal cord injury regeneration

, 2013
Eduardo D. Gomes
openalex   +1 more source