Results 21 to 30 of about 3,276 (98)

New insights in application of mesenchymal stem cells therapy in tumor microenvironment: pros and cons

open access: yesFrontiers in Cell and Developmental Biology, 2023
Multipotent mesenchymal stem cells (MSCs) are widely accepted as a useful tool for cell-based therapy of various diseases including malignancies. The therapeutic effects of MSCs are mainly attributed to their immunomodulatory and immunosuppressive ...
Hamed Afkhami   +9 more
doaj   +1 more source

Thrombogenic Risk Induced by Intravascular Mesenchymal Stem Cell Therapy: Current Status and Future Perspectives

open access: yesCells, 2019
Mesenchymal stem cells (MSCs) are currently studied and used in numerous clinical trials. Nevertheless, some concerns have been raised regarding the safety of these infusions and the thrombogenic risk they induce. MSCs express procoagulant activity (PCA)
Louise Coppin   +2 more
doaj   +1 more source

ICOS and OX40 tandem co-stimulation enhances CAR T-cell cytotoxicity and promotes T-cell persistence phenotype

open access: yesFrontiers in Oncology, 2023
Chimeric Antigen Receptor (CAR) T-cell therapies have emerged as an effective and potentially curative immunotherapy for patients with relapsed or refractory malignancies.
Eider Moreno-Cortes   +13 more
doaj   +1 more source

Clinical Application of Exosomes for COVID-19 and Diagnosis

open access: yesKorean Journal of Clinical Laboratory Science
Exosomes are nano-sized membrane-bound extracellular vesicles containing various biological molecules, such as nucleic acids, proteins, and lipids, which can be used to modulate physiological processes.
June Seok HEO
doaj   +1 more source

Localized Perivascular Therapeutic Approaches to Inhibit Venous Neointimal Hyperplasia in Arteriovenous Fistula Access for Hemodialysis Use

open access: yesBiomolecules, 2022
An arteriovenous fistula (AVF) is the preferred vascular access for chronic hemodialysis, but high failure rates restrict its use. Optimizing patients’ perioperative status and the surgical technique, among other methods for preventing primary AVF ...
Allan John R. Barcena   +6 more
doaj   +1 more source

Cardiac tissue engineering and regeneration using cell-based therapy

open access: yesStem Cells and Cloning: Advances and Applications, 2015
Mohammad T Alrefai,1–3 Divya Murali,4 Arghya Paul,4 Khalid M Ridwan,1,2 John M Connell,1,2 Dominique Shum-Tim1,2 1Division of Cardiac Surgery, 2Division of Surgical Research, McGill University Health Center, Montreal, QC, Canada; 3King Faisal ...
Alrefai MT   +5 more
doaj  

A Revolution in Cellular Aging: A Narrative Review of the Promising Role of Nanorobots in Diagnosis, Treatment, and Regenerative Medicine [PDF]

open access: yesTaṣvīr-i salāmat
Nanorobots, also known as nanobots, are promising medical structures with significant potential for revolutionizing medical treatments and preventing their onset. Nanorobotics shows promise for diagnosing, treating, and regenerating age-related diseases.
Peyman Keyhanvar   +4 more
doaj   +1 more source

Strategies for Achieving Measurement Assurance for Cell Therapy Products

open access: yesStem Cells Translational Medicine, 2016
The cell therapy industry has identified the inability to reliably characterize cells as possibly its greatest challenge and has called for standards and reference materials to provide assurance for measurements of cell properties.
Carl G. Simon Jr.   +4 more
doaj   +1 more source

Transcriptomic comparisons between cultured human adipose tissue-derived pericytes and mesenchymal stromal cells

open access: yesGenomics Data, 2016
Mesenchymal stromal cells (MSCs), sometimes called mesenchymal stem cells, are cultured cells able to give rise to mature mesenchymal cells such as adipocytes, osteoblasts, and chondrocytes, and to secrete a wide range of trophic and immunomodulatory ...
Lindolfo da Silva Meirelles   +3 more
doaj  

Cardiac Tissue Engineering for the Treatment of Myocardial Infarction

open access: yesJournal of Cardiovascular Development and Disease, 2021
Poor cell engraftment rate is one of the primary factors limiting the effectiveness of cell transfer therapy for cardiac repair. Recent studies have shown that the combination of cell-based therapy and tissue engineering technology can improve stem cell ...
Dongmin Yu, Xiaowei Wang, Lei Ye
doaj   +1 more source

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