Results 21 to 30 of about 1,085,002 (240)

Cell-derived extracellular vesicles and membranes for tissue repair

Journal of Nanobiotechnology, 2021
Humans have a limited postinjury regenerative ability. Therefore, cell-derived biomaterials have long been utilized for tissue repair. Cells with multipotent differentiation potential, such as stem cells, have been administered to patients for the ...
Yuan Ding, Yanjie Li, Zhongquan Sun, Xin Han, Yining Chen, Yao Ge, Zhengwei Mao, Weilin Wang   +7 more
doaj   +1 more source

Translating the combination of gene therapy and tissue engineering for treating recessive dystrophic epidermolysis bullosa [PDF]

European Cells & Materials, 2018
The combination of gene therapy and tissue engineering is one of the most promising strategies for the treatment of recessive dystrophic epidermolysis bullosa (RDEB).
A Dakiw Piaceski, D Larouche, K Ghani, F Bisson, S Cortez Ghio, S Larochelle, VJ Moulin, M Caruso, L Germain   +8 more
doaj   +1 more source

Hydrogel-Based Non-Autologous Cell and Tissue Therapy

BioTechniques, 2000
Many diseases are closely tied to deficient or subnormal metabolic and secretory cell functions. Milder forms of these diseases can be managed by a variety of treatments.
U. Zimmermann, S. Mimietz, H. Zimmermann, M. Hillgärtner, H. Schneider, J. Ludwig, C. Hasse, A. Haase, M. Rothmund, G. Fuhr   +9 more
doaj   +1 more source

Regenerative Medicine for the Kidney [PDF]

Urogenital Tract Infection
Kidney disease poses a major and growing global health challenge, with both prevalence and mortality continuing to rise. Current standard-of-care treatments, including dialysis and kidney transplantation, have significant limitations and do not ...
Vladimir Mashanov, Ji Hyun Kim
doaj   +1 more source

Thrombogenic Risk Induced by Intravascular Mesenchymal Stem Cell Therapy: Current Status and Future Perspectives

Cells, 2019
Mesenchymal stem cells (MSCs) are currently studied and used in numerous clinical trials. Nevertheless, some concerns have been raised regarding the safety of these infusions and the thrombogenic risk they induce. MSCs express procoagulant activity (PCA)
Louise Coppin, Etienne Sokal, Xavier Stéphenne   +2 more
doaj   +1 more source

Matrix-assisted autologous chondrocyte transplantation for treatment of focal chondral lesions in the knee: the Hospital Israelita Albert Einstein experience

Einstein (São Paulo), 2022
Objective Phase 1 clinical trial to determine feasibility, safety, and efficacy of a new advanced cell therapy product for treatment of knee articular cartilage injuries.
Alessandro Rozim Zorzi, Eliane Antonioli, Camila Cohen Kaleka, Moisés Cohen, Juliana Aparecida Preto de Godoy, Andrea Tiemi Kondo, José Mauro Kutner, Mario Lenza, Mario Ferretti   +8 more
doaj   +1 more source

New insights in application of mesenchymal stem cells therapy in tumor microenvironment: pros and cons

Frontiers in Cell and Developmental Biology, 2023
Multipotent mesenchymal stem cells (MSCs) are widely accepted as a useful tool for cell-based therapy of various diseases including malignancies. The therapeutic effects of MSCs are mainly attributed to their immunomodulatory and immunosuppressive ...
Hamed Afkhami, Hamed Afkhami, Hamed Afkhami, Golnaz Mahmoudvand, Arshia Fakouri, Alireza Shadab, Alireza Shadab, Mohamad Mahjoor, Mohamad Mahjoor, Tahereh Komeili Movahhed   +9 more
doaj   +1 more source

Evaluation of silver nitroprusside nanoparticles: selective toxicity against MCF-7 cells and in vivo antitumor activity

Discover Nano
A number of different metallic nanoparticles have been extensively investigated in recent years owing to their diverse potential biomedical and cancer applications, antibacterial activities, and chemical properties.
Daniela Silvestrini Fernandes, Cristiano Ceron Jayme, Flavia Sayuri Matsuo, Sarah Caroline Gomes de Lima, Daianne Maciely Carvalho Fantacini, Lucas Eduardo Botelho de Souza, Antonio Claudio Tedesco   +6 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source