Results 241 to 250 of about 1,959,228 (334)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Functional characterization of SORL1 variants in cell-based assays to investigate variant pathogenicity. [PDF]

Philos Trans R Soc Lond B Biol Sci
Fazeli E, Fazeli E, Fojtík P, Holstege H, Andersen OM.   +4 more
europepmc   +1 more source

Antiretroviral effect of 4-thio-uridylate against human immunodeficiency virus type 1 [PDF]

, 2012
Albert J., Barbouche R., Beck Z., Berger E. A., Clapham P., Cox S., Doms R. W., Einfeld D., Fenouillet E., Horváth A., Horváth A., Joseph Ongrádi, Juhász E., Kanizsai S., Kanizsai Sz., Kemény B., Kilby J. M., Károly Nagy, Leonard C., Markovic I., Matthias L. J., Nagy K., Nagy K., Nagy K., Nisole S., Ou W., Ryser H. J., Szatmari I., Szilvia Kanizsai, Tarkanyi I., Tõkés S., Wittinghoff E., Ágoston Ghidán   +32 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Establishing a Relationship between In Vitro Potency in Cell-Based Assays and Clinical Efficacious Concentrations for Approved GLP-1 Receptor Agonists. [PDF]

Pharmaceutics
Boianelli A, Nordell P, Earl J, Naylor J, Hornigold D, Jansson Löfmark R, Sundqvist M.   +6 more
europepmc   +1 more source

Development of a cell-based DIFF-rGFP assay system for generalized discovery of viral protease Inhibitors [PDF]

Xiaoyan Wu, Feng Yan, Rui-ting Chen, FANG Chenjie, Shuai Wang, S Hen Hui-min, JIAN Shuling, Jiasheng Song, WU Beibei   +8 more
openalex   +1 more source

A microtiter-plate-based cytochrome P450 3A activity assay in fish cell lines [PDF]

, 2009
Verena Christen, Daniela M. Oggier, Karl Fent   +2 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Selective Elimination and Rationalization of Cell-based Assays in Deceased Donor Kidney Transplant Crossmatching. [PDF]

Transplant Direct
Khalili M, Famure O, Minkovich M, Tinckam KJ, Kim SJ.   +4 more
europepmc   +1 more source

Cellaxess®HT cell-based assay and transfection lab [PDF]

, 2011
Sara Aspengren, Michael Tokarz, Johan Pihl   +2 more
openalex   +1 more source