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Development of a Cell-based Diabetic Wound Assay
Alternatives to Laboratory Animals, 2010Chronic wounds require prolonged healthcare and adversely affect the quality of life of patients. They are particularly prominent in patients with diabetes, and their relative numbers are set to increase with the rise of diabetes within our population.
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Cell‐based assays in GPCR drug discovery
Biotechnology Journal, 2008AbstractG protein‐coupled receptors (GPCRs) transmit extracellular signals into the intracellular space, and play key roles in the physiological regulation of virtually every cell and tissue. Characteristic for the GPCR superfamily of cell surface receptors are their seven transmembrane‐spanning α‐helices, an extracellular N terminus and intracellular ...
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Cell-Based Assays to Study SUMOylation in Drosophila
SUMOylation (Small Ubiquitin-like Modifiers, SUMO group) is known to regulate protein-protein interactions, subcellular localization, and the activities of SUMO-modified targets. Over the past two decades, the SUMO pathway has been implicated in numerous developmental processes in Drosophila, including embryogenesis, wing morphogenesis, innate immune ...Mengmeng, Zhou, Yuhong, Han, Jin, Jiang
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Cell Based Assays for Drug Screening
1997A CRE-alkaline Phosphatase reporter construct has been introduced into a mammalian cell line to investigate signal transduction pathways used by the calcitonin receptor. Calcitonin activated alkaline Phosphatase production in the CRE-reporter cell line.
Elizabeth Keenan +3 more
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Live Cell Assays for the Assessment of Antioxidant Activities of Plant Extracts
Antioxidants, 2021Christophe Furger
exaly
Cell-based assay for monitoring transglutaminase activity
Analytical Biochemistry, 2004Ju-Hong, Jeon +8 more
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IDrugs : the investigational drugs journal, 2010
Informa Life Sciences' Fifth Annual Conference on Cell-Based Assays, held in Cologne, Germany, included topics covering new technical developments in the field of cell-based assays. This conference report highlights selected presentations on cell-based assays for compound screening and 3D cell-based assays.
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Informa Life Sciences' Fifth Annual Conference on Cell-Based Assays, held in Cologne, Germany, included topics covering new technical developments in the field of cell-based assays. This conference report highlights selected presentations on cell-based assays for compound screening and 3D cell-based assays.
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Perspective: diagnostic laboratories should urgently develop T cell assays for SARS-CoV-2 infection
Expert Review of Clinical Immunology, 2021Rohan Ameratunga +2 more
exaly