Cell-derived microparticles and the lung [PDF]
European Respiratory Review, 2016 Cell-derived microparticles are small (0.1–1 μm) vesicles shed by most eukaryotic cells upon activation or during apoptosis. Microparticles carry on their surface, and enclose within their cytoplasm, molecules derived from the parental cell, including ...
Dario Nieri +5 more
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Engineered Cell‐Derived Microparticles Bi2Se3/DOX@MPs for Imaging Guided Synergistic Photothermal/Low‐Dose Chemotherapy of Cancer [PDF]
Advanced Science, 2020 Cell‐derived microparticles, which are recognized as nanosized phospholipid bilayer membrane vesicles, have exhibited great potential to serve as drug delivery systems in cancer therapy.
Dongdong Wang +14 more
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Nano-zymography Using Laser-Scanning Confocal Microscopy Unmasks Proteolytic Activity of Cell-Derived Microparticles. [PDF]
Theranostics, 2016 Cell-derived microparticles (MPs) are nano-sized vesicles released by activated cells in the extracellular milieu. They act as vectors of biological activity by carrying membrane-anchored and cytoplasmic constituents of the parental cells.
Briens A +5 more
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Tumor-repopulating cell-derived microparticles elicit cascade amplification of chemotherapy-induced antitumor immunity to boost anti-PD-1 therapy. [PDF]
Signal Transduct Target Ther, 2023 Immune checkpoint blockade (ICB) therapy, particularly antibodies targeting the programmed death receptor 1 (PD-1) and its ligand (PD-L1), has revolutionized cancer treatment. However, its efficacy as a standalone therapy remains limited.
Bie N +9 more
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Irradiated tumor cell-derived microparticles mediate tumor eradication via cell killing and immune reprogramming. [PDF]
Sci Adv, 2020 By mimicking the RIBE machinery, we provided an indirect radiotherapy approach based on RT-MP for eradication of MPE in mice. Radiotherapy (RT) is routinely used in cancer treatment, but expansion of its clinical indications remains challenging.
Wan C +15 more
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Catabolic effects of endothelial cell-derived microparticles on disc cells: Implications in intervertebral disc neovascularization and degeneration. [PDF]
J Orthop Res, 2016 Pohl PH +11 more
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Hemoglobin oxidation-dependent reactions promote interactions with band 3 and oxidative changes in sickle cell-derived microparticles. [PDF]
JCI Insight, 2018 The contribution of intracellular hemoglobin (Hb) oxidation to RBC-derived microparticle (MP) formation is poorly defined in sickle cell disease (SCD).
Jana S +11 more
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Correlations Between the Circulating Level of Cell-Derived Microparticles and Surgical Variables in Heart Valve Surgery with Cardiopulmonary Bypass [PDF]
Journal of Tehran University Heart Center, 2022 Background: Cell-derived microparticles (MPs) as membrane vesicles are procoagulant. They play a role in surgical hemostasis. In this study, the correlations between the circulating level of cell-derived MPs and surgical variables in heart valve surgery
Mehrnaz Abdolalian +4 more
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Influence of red blood cell-derived microparticles upon vasoregulation. [PDF]
Blood Transfus, 2017 Here we review recent data and the evolving understanding of the role of red blood cell-derived microparticles (RMPs) in normal physiology and in disease progression. Microparticles (MPs) are small membrane vesicles derived from various parent cell types.
Said AS, Doctor A.
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Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progression. [PDF]
Oncoimmunology, 2016 Despite identification of macrophages in tumors (tumor-associated macrophages, TAM) as potential targets for cancer therapy, the origin and function of TAM in the context of malignancy remain poorly characterized. Here, we show that microparticles (MPs),
Ma R +11 more
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